BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 9822218)

  • 1. Intrinsic reactivity of tamoxifen and toremifene metabolites with DNA.
    Hellmann-Blumberg U; Cartner MG; Wurz GT; DeGregorio MW
    Breast Cancer Res Treat; 1998 Jul; 50(2):135-41. PubMed ID: 9822218
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genotoxic effects of the novel mixed antiestrogen FC-1271a in comparison to tamoxifen and toremifene.
    Hellmann-Blumberg U; Taras TL; Wurz GT; DeGregorio MW
    Breast Cancer Res Treat; 2000 Mar; 60(1):63-70. PubMed ID: 10845810
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA adduct formation in the livers of female Sprague-Dawley rats treated with toremifene or alpha-hydroxytoremifene.
    Gamboa da Costa G; Pereira PC; Churchwell MI; Beland FA; Marques MM
    Chem Res Toxicol; 2007 Feb; 20(2):300-10. PubMed ID: 17261033
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tamoxifen metabolic activation: comparison of DNA adducts formed by microsomal and chemical activation of tamoxifen and 4-hydroxytamoxifen with DNA adducts formed in vivo.
    Moorthy B; Sriram P; Pathak DN; Bodell WJ; Randerath K
    Cancer Res; 1996 Jan; 56(1):53-7. PubMed ID: 8548775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Electrospray ionization-tandem mass spectrometry and 32P-postlabeling analyses of tamoxifen-DNA adducts in humans.
    Beland FA; Churchwell MI; Doerge DR; Parkin DR; Malejka-Giganti D; Hewer A; Phillips DH; Carmichael PL; Gamboa da Costa G; Marques MM
    J Natl Cancer Inst; 2004 Jul; 96(14):1099-104. PubMed ID: 15265972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA adduct formation and mutant induction in Sprague-Dawley rats treated with tamoxifen and its derivatives.
    Gamboa da Costa G; McDaniel-Hamilton LP; Heflich RH; Marques MM; Beland FA
    Carcinogenesis; 2001 Aug; 22(8):1307-15. PubMed ID: 11470763
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA adduct formation by tamoxifen and structurally-related compounds in rat liver.
    Rajaniemi H; Mäntylä E; Hemminki K
    Chem Biol Interact; 1998 May; 113(2):145-59. PubMed ID: 9717515
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the major DNA adduct formed by alpha-hydroxy-N-desmethyltamoxifen in vitro and in vivo.
    Gamboa da Costa G; Hamilton LP; Beland FA; Marques MM
    Chem Res Toxicol; 2000 Mar; 13(3):200-7. PubMed ID: 10725117
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tamoxifen and toremifene in breast cancer: comparison of safety and efficacy.
    Buzdar AU; Hortobagyi GN
    J Clin Oncol; 1998 Jan; 16(1):348-53. PubMed ID: 9440763
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of lower genotoxicity of toremifene compared with tamoxifen.
    Shibutani S; Ravindernath A; Terashima I; Suzuki N; Laxmi YR; Kanno Y; Suzuki M; Apak TI; Sheng JJ; Duffel MW
    Cancer Res; 2001 May; 61(10):3925-31. PubMed ID: 11358807
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts.
    Davies AM; Martin EA; Jones RM; Lim CK; Smith LL; White IN
    Carcinogenesis; 1995 Mar; 16(3):539-45. PubMed ID: 7697811
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of evidence for tamoxifen- and toremifene-DNA adducts in lymphocytes of treated patients.
    Bartsch H; Phillips DH; Nair J; Hewer A; Meyberg-Solomeyer G; Grischke EM
    Carcinogenesis; 2000 Apr; 21(4):845-7. PubMed ID: 10753226
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational studies and electronic structures of tamoxifen and toremifene and their allylic carbocations proposed as reactive intermediates leading to DNA adduct formation.
    Kuramochi H
    J Med Chem; 1996 Jul; 39(15):2877-86. PubMed ID: 8709121
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Organ specificity of DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen in the rat: implications for understanding the mechanism(s) of tamoxifen carcinogenicity and for human risk assessment.
    Phillips DH; Hewer A; Osborne MR; Cole KJ; Churchill C; Arlt VM
    Mutagenesis; 2005 Jul; 20(4):297-303. PubMed ID: 15928012
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
    Randerath K; Moorthy B; Mabon N; Sriram P
    Carcinogenesis; 1994 Oct; 15(10):2087-94. PubMed ID: 7955037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
    Fan PW; Zhang F; Bolton JL
    Chem Res Toxicol; 2000 Jan; 13(1):45-52. PubMed ID: 10649966
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones.
    Yao D; Zhang F; Yu L; Yang Y; van Breemen RB; Bolton JL
    Chem Res Toxicol; 2001 Dec; 14(12):1643-53. PubMed ID: 11743747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adducts and tamoxifen.
    Busch H
    Semin Oncol; 1997 Feb; 24(1 Suppl 1):S1-98-S1-104. PubMed ID: 9045322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes.
    Phillips DH; Carmichael PL; Hewer A; Cole KJ; Poon GK
    Cancer Res; 1994 Nov; 54(21):5518-22. PubMed ID: 7923188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tamoxifen-DNA adducts formed by alpha-acetoxytamoxifen N-oxide.
    Umemoto A; Monden Y; Komaki K; Suwa M; Kanno Y; Suzuki M; Lin CX; Ueyama Y; Momen MA; Ravindernath A; Shibutani S
    Chem Res Toxicol; 1999 Nov; 12(11):1083-9. PubMed ID: 10563834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.