116 related articles for article (PubMed ID: 9839002)
1. 2,2'-Dithiobisbenzamides derived from alpha-, beta- and gamma-amino acids possessing anti-HIV activities: synthesis and structure-activity relationship.
Prasad JV; Loo JA; Boyer FE; Stier MA; Gogliotti RD; Turner WJ; Harvey PJ; Kramer MR; Mack DP; Scholten JD; Gracheck SJ; Domagala JM
Bioorg Med Chem; 1998 Oct; 6(10):1707-30. PubMed ID: 9839002
[TBL] [Abstract][Full Text] [Related]
2. A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: the 2,2'-dithiobisbenzamides.
Domagala JM; Bader JP; Gogliotti RD; Sanchez JP; Stier MA; Song Y; Prasad JV; Tummino PJ; Scholten J; Harvey P; Holler T; Gracheck S; Hupe D; Rice WG; Schultz R
Bioorg Med Chem; 1997 Mar; 5(3):569-79. PubMed ID: 9113335
[TBL] [Abstract][Full Text] [Related]
3. The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities.
Tummino PJ; Harvey PJ; McQuade T; Domagala J; Gogliotti R; Sanchez J; Song Y; Hupe D
Antimicrob Agents Chemother; 1997 Feb; 41(2):394-400. PubMed ID: 9021197
[TBL] [Abstract][Full Text] [Related]
4. Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
Huang M; Maynard A; Turpin JA; Graham L; Janini GM; Covell DG; Rice WG
J Med Chem; 1998 Apr; 41(9):1371-81. PubMed ID: 9554870
[TBL] [Abstract][Full Text] [Related]
5. Biophysical characterization of zinc ejection from HIV nucleocapsid protein by anti-HIV 2,2'-dithiobis[benzamides] and benzisothiazolones.
Loo JA; Holler TP; Sanchez J; Gogliotti R; Maloney L; Reily MD
J Med Chem; 1996 Oct; 39(21):4313-20. PubMed ID: 8863808
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of HIV-1 nucleocapsid protein P7 by pyridinioalkanoyl thioesters. Characterization of reaction products and proposed mechanism of action.
Basrur V; Song Y; Mazur SJ; Higashimoto Y; Turpin JA; Rice WG; Inman JK; Appella E
J Biol Chem; 2000 May; 275(20):14890-7. PubMed ID: 10809733
[TBL] [Abstract][Full Text] [Related]
7. A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.
Druillennec S; Dong CZ; Escaich S; Gresh N; Bousseau A; Roques BP; Fournié-Zaluski MC
Proc Natl Acad Sci U S A; 1999 Apr; 96(9):4886-91. PubMed ID: 10220388
[TBL] [Abstract][Full Text] [Related]
8. Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.
Jenkins LM; Byrd JC; Hara T; Srivastava P; Mazur SJ; Stahl SJ; Inman JK; Appella E; Omichinski JG; Legault P
J Med Chem; 2005 Apr; 48(8):2847-58. PubMed ID: 15828823
[TBL] [Abstract][Full Text] [Related]
9. Benzamide-based thiolcarbamates: a new class of HIV-1 NCp7 inhibitors.
Goel A; Mazur SJ; Fattah RJ; Hartman TL; Turpin JA; Huang M; Rice WG; Appella E; Inman JK
Bioorg Med Chem Lett; 2002 Mar; 12(5):767-70. PubMed ID: 11858998
[TBL] [Abstract][Full Text] [Related]
10. 2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations.
Domagala JM; Gogliotti R; Sanchez JP; Stier MA; Musa K; Song Y; Loo J; Reily M; Tummino P; Harvey P; Hupe D; Sharmeen L; Mack D; Scholten J; Saunders J; McQuade T
Drug Des Discov; 1997 May; 15(1):49-61. PubMed ID: 9332831
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.
Rice WG; Baker DC; Schaeffer CA; Graham L; Bu M; Terpening S; Clanton D; Schultz R; Bader JP; Buckheit RW; Field L; Singh PK; Turpin JA
Antimicrob Agents Chemother; 1997 Feb; 41(2):419-26. PubMed ID: 9021201
[TBL] [Abstract][Full Text] [Related]
12. New developments in anti-HIV chemotherapy.
De Clercq E
Curr Med Chem; 2001 Nov; 8(13):1543-72. PubMed ID: 11562282
[TBL] [Abstract][Full Text] [Related]
13. 1H NMR structure and biological studies of the His23-->Cys mutant nucleocapsid protein of HIV-1 indicate that the conformation of the first zinc finger is critical for virus infectivity.
Déméné H; Dong CZ; Ottmann M; Rouyez MC; Jullian N; Morellet N; Mely Y; Darlix JL; Fournié-Zaluski MC; Saragosti S
Biochemistry; 1994 Oct; 33(39):11707-16. PubMed ID: 7918387
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
[TBL] [Abstract][Full Text] [Related]
15. Structure, biological functions and inhibition of the HIV-1 proteins Vpr and NCp7.
Roques BP; Morellet N; de Rocquigny H; Déméné H; Schueler W; Jullian N
Biochimie; 1997 Nov; 79(11):673-80. PubMed ID: 9479450
[TBL] [Abstract][Full Text] [Related]
16. Analysis of NCp7-dependent activation of HIV-1 cDNA integration and its conservation among retroviral nucleocapsid proteins.
Poljak L; Batson SM; Ficheux D; Roques BP; Darlix JL; Käs E
J Mol Biol; 2003 Jun; 329(3):411-21. PubMed ID: 12767826
[TBL] [Abstract][Full Text] [Related]
17. New anti-HIV agents and targets.
De Clercq E
Med Res Rev; 2002 Nov; 22(6):531-65. PubMed ID: 12369088
[TBL] [Abstract][Full Text] [Related]
18. Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.
Rice WG; Turpin JA; Huang M; Clanton D; Buckheit RW; Covell DG; Wallqvist A; McDonnell NB; DeGuzman RN; Summers MF; Zalkow L; Bader JP; Haugwitz RD; Sausville EA
Nat Med; 1997 Mar; 3(3):341-5. PubMed ID: 9055865
[TBL] [Abstract][Full Text] [Related]
19. NMR structure of the complex between the zinc finger protein NCp10 of Moloney murine leukemia virus and the single-stranded pentanucleotide d(ACGCC): comparison with HIV-NCp7 complexes.
Schüler W; Dong C; Wecker K; Roques BP
Biochemistry; 1999 Oct; 38(40):12984-94. PubMed ID: 10529168
[TBL] [Abstract][Full Text] [Related]
20. New developments in anti-HIV chemotherapy.
De Clercq E
Biochim Biophys Acta; 2002 Jul; 1587(2-3):258-75. PubMed ID: 12084468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
