BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

872 related articles for article (PubMed ID: 9839089)

  • 1. Inhibition and induction of cytochrome P450 and the clinical implications.
    Lin JH; Lu AY
    Clin Pharmacokinet; 1998 Nov; 35(5):361-90. PubMed ID: 9839089
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of the in vitro and in vivo metabolic pathway and cytochrome P450 inhibition/induction profile of Huperzine A.
    Lin PP; Li XN; Yuan F; Chen WL; Yang MJ; Xu HR
    Biochem Biophys Res Commun; 2016 Nov; 480(2):248-253. PubMed ID: 27751854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of metabolites in predicting drug-drug interactions: focus on irreversible cytochrome P450 inhibition.
    VandenBrink BM; Isoherranen N
    Curr Opin Drug Discov Devel; 2010 Jan; 13(1):66-77. PubMed ID: 20047147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50).
    Gao F; Johnson DL; Ekins S; Janiszewski J; Kelly KG; Meyer RD; West M
    J Biomol Screen; 2002 Aug; 7(4):373-82. PubMed ID: 12230892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinically important pharmacokinetic drug-drug interactions: role of cytochrome P450 enzymes.
    Tanaka E
    J Clin Pharm Ther; 1998 Dec; 23(6):403-16. PubMed ID: 10048501
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions.
    Bertz RJ; Granneman GR
    Clin Pharmacokinet; 1997 Mar; 32(3):210-58. PubMed ID: 9084960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Utility of microtiter plate assays for human cytochrome P450 inhibition studies in drug discovery: application of simple method for detecting quasi-irreversible and irreversible inhibitors.
    Naritomi Y; Teramura Y; Terashita S; Kagayama A
    Drug Metab Pharmacokinet; 2004 Feb; 19(1):55-61. PubMed ID: 15499170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.
    Bredberg E; Andersson TB; Frison L; Thuresson A; Johansson S; Eriksson-Lepkowska M; Larsson M; Eriksson UG
    Clin Pharmacokinet; 2003; 42(8):765-77. PubMed ID: 12846597
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms and significance of inhibitory drug interactions involving cytochrome P450 enzymes (review).
    Murray M
    Int J Mol Med; 1999 Mar; 3(3):227-38. PubMed ID: 10028046
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4.
    Zhou S; Chan E; Lim LY; Boelsterli UA; Li SC; Wang J; Zhang Q; Huang M; Xu A
    Curr Drug Metab; 2004 Oct; 5(5):415-42. PubMed ID: 15544435
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytochrome P450-mediated metabolism in the human gut wall.
    Thelen K; Dressman JB
    J Pharm Pharmacol; 2009 May; 61(5):541-58. PubMed ID: 19405992
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.
    Walker DK; Alabaster CT; Congrave GS; Hargreaves MB; Hyland R; Jones BC; Reed LJ; Smith DA
    Drug Metab Dispos; 1996 Apr; 24(4):447-55. PubMed ID: 8801060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies.
    Donato MT; Castell JV
    Clin Pharmacokinet; 2003; 42(2):153-78. PubMed ID: 12537515
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P450 Structure, Function and Clinical Significance: A Review.
    Manikandan P; Nagini S
    Curr Drug Targets; 2018; 19(1):38-54. PubMed ID: 28124606
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytochrome P450s in the development of target-based anticancer drugs.
    Purnapatre K; Khattar SK; Saini KS
    Cancer Lett; 2008 Jan; 259(1):1-15. PubMed ID: 18053638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Fontana E; Dansette PM; Poli SM
    Curr Drug Metab; 2005 Oct; 6(5):413-54. PubMed ID: 16248836
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enzyme kinetics for clinically relevant CYP inhibition.
    Zhang ZY; Wong YN
    Curr Drug Metab; 2005 Jun; 6(3):241-57. PubMed ID: 15975042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions of herbs with cytochrome P450.
    Zhou S; Gao Y; Jiang W; Huang M; Xu A; Paxton JW
    Drug Metab Rev; 2003 Feb; 35(1):35-98. PubMed ID: 12635815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction.
    Kumar G; Lau H; Laskin O
    Cancer Chemother Pharmacol; 2009 May; 63(6):1171-5. PubMed ID: 19030860
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.
    Zheng YF; Bae SH; Choi EJ; Park JB; Kim SO; Jang MJ; Park GH; Shin WG; Oh E; Bae SK
    Food Chem Toxicol; 2014 Jun; 68():117-27. PubMed ID: 24632066
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.