These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

992 related articles for article (PubMed ID: 9843428)

  • 1. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
    Munagala NR; Wang CC
    Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
    Munagala NR; Chin MS; Wang CC
    Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
    Xu Y; Grubmeyer C
    Biochemistry; 1998 Mar; 37(12):4114-24. PubMed ID: 9521733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
    Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
    Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment.
    Pitera JW; Munagala NR; Wang CC; Kollman PA
    Biochemistry; 1999 Aug; 38(32):10298-306. PubMed ID: 10441123
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.
    Ullman B; Cyr N; Choi K; Jardim A
    Int J Biochem Cell Biol; 2010 Feb; 42(2):253-62. PubMed ID: 19861168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
    Somoza JR; Chin MS; Focia PJ; Wang CC; Fletterick RJ
    Biochemistry; 1996 Jun; 35(22):7032-40. PubMed ID: 8679528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis.
    Munagala N; Basus VJ; Wang CC
    Biochemistry; 2001 Apr; 40(14):4303-11. PubMed ID: 11284686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
    Gogia S; Balaram H; Puranik M
    Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine.
    Lee CC; Craig SP; Eakin AE
    Biochemistry; 1998 Mar; 37(10):3491-8. PubMed ID: 9521670
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan.
    Somoza JR; Skillman AG; Munagala NR; Oshiro CM; Knegtel RM; Mpoke S; Fletterick RJ; Kuntz ID; Wang CC
    Biochemistry; 1998 Apr; 37(16):5344-8. PubMed ID: 9548915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivation of Tritrichomonas foetus and Schistosoma mansoni purine phosphoribosyltransferases by arginine-specific reagents.
    Kanaani J; Maltby D; Somoza JR; Wang CC
    Eur J Biochem; 1997 Mar; 244(3):810-7. PubMed ID: 9108251
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity.
    Raman J; Sumathy K; Anand RP; Balaram H
    Arch Biochem Biophys; 2004 Jul; 427(1):116-22. PubMed ID: 15178494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.
    Page JP; Munagala NR; Wang CC
    Eur J Biochem; 1999 Feb; 259(3):565-71. PubMed ID: 10092838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
    Xu Y; Eads J; Sacchettini JC; Grubmeyer C
    Biochemistry; 1997 Mar; 36(12):3700-12. PubMed ID: 9132023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus.
    Hedstrom L; Cheung KS; Wang CC
    Biochem Pharmacol; 1990 Jan; 39(1):151-60. PubMed ID: 1967525
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase.
    Vos S; Parry RJ; Burns MR; de Jersey J; Martin JL
    J Mol Biol; 1998 Oct; 282(4):875-89. PubMed ID: 9743633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus has unique properties.
    Beck JT; Wang CC
    Mol Biochem Parasitol; 1993 Aug; 60(2):187-94. PubMed ID: 8232411
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ile209 of Leishmania donovani xanthine phosphoribosyltransferase plays a key role in determining its purine base specificity.
    Patel B; Patel D; Pappachan A
    FEBS Lett; 2021 Aug; 595(16):2169-2182. PubMed ID: 34268726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
    Lu F; Schumacher MA; Arvidson DN; Haldimann A; Wanner BL; Zalkin H; Brennan RG
    Biochemistry; 1998 Jan; 37(4):971-82. PubMed ID: 9454587
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 50.