These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 9843689)

  • 1. Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells.
    Rosen K; Rak J; Jin J; Kerbel RS; Newman MJ; Filmus J
    Curr Biol; 1998 Dec; 8(24):1331-4. PubMed ID: 9843689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells.
    Rosen K; Rak J; Leung T; Dean NM; Kerbel RS; Filmus J
    J Cell Biol; 2000 Apr; 149(2):447-56. PubMed ID: 10769035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm.
    Liu Z; Li H; Derouet M; Berezkin A; Sasazuki T; Shirasawa S; Rosen K
    J Biol Chem; 2006 May; 281(21):14738-47. PubMed ID: 16461771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells.
    Yoo BH; Wang Y; Erdogan M; Sasazuki T; Shirasawa S; Corcos L; Sabapathy K; Rosen KV
    J Biol Chem; 2011 Nov; 286(45):38894-903. PubMed ID: 21903589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.
    Liu Z; Li H; Derouet M; Filmus J; LaCasse EC; Korneluk RG; Kerbel RS; Rosen KV
    J Biol Chem; 2005 Nov; 280(45):37383-92. PubMed ID: 16115895
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells.
    Yoo BH; Berezkin A; Wang Y; Zagryazhskaya A; Rosen KV
    Int J Cancer; 2012 Jul; 131(2):357-66. PubMed ID: 21834075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts.
    Rak J; Mitsuhashi Y; Sheehan C; Tamir A; Viloria-Petit A; Filmus J; Mansour SJ; Ahn NG; Kerbel RS
    Cancer Res; 2000 Jan; 60(2):490-8. PubMed ID: 10667605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
    McFall A; Ulkü A; Lambert QT; Kusa A; Rogers-Graham K; Der CJ
    Mol Cell Biol; 2001 Aug; 21(16):5488-99. PubMed ID: 11463831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells.
    Rosen K; Coll ML; Li A; Filmus J
    J Biol Chem; 2001 Oct; 276(40):37273-9. PubMed ID: 11487584
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression.
    Rak J; Mitsuhashi Y; Erdos V; Huang SN; Filmus J; Kerbel RS
    J Cell Biol; 1995 Dec; 131(6 Pt 1):1587-98. PubMed ID: 8522614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells.
    Tchernitsa OI; Sers C; Zuber J; Hinzmann B; Grips M; Schramme A; Lund P; Schwendel A; Rosenthal A; Schäfer R
    Oncogene; 2004 Jun; 23(26):4536-55. PubMed ID: 15064704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells.
    Khan IA; Yoo BH; Masson O; Baron S; Corkery D; Dellaire G; Attardi LD; Rosen KV
    Oncogene; 2016 Nov; 35(44):5759-5769. PubMed ID: 27109096
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells.
    Yoo BH; Wu X; Li Y; Haniff M; Sasazuki T; Shirasawa S; Eskelinen EL; Rosen KV
    J Biol Chem; 2010 Feb; 285(8):5438-49. PubMed ID: 19778902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells.
    Nguyen KT; Wang WJ; Chan JL; Wang LH
    Oncogene; 2000 Nov; 19(47):5385-97. PubMed ID: 11103940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Malignant transformation of normal enterocytes following downregulation of Bak expression.
    Liberman E; Naumov I; Kazanov D; Dvory-Sobol H; Sagiv E; Birkenfeld S; Deutsch V; Trakhtenbrot L; Moshkowitz M; Arber N
    Digestion; 2008; 77(1):48-56. PubMed ID: 18349538
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ras-Induced up-regulation of CTP:phosphocholine cytidylyltransferase α contributes to malignant transformation of intestinal epithelial cells.
    Arsenault DJ; Yoo BH; Rosen KV; Ridgway ND
    J Biol Chem; 2013 Jan; 288(1):633-43. PubMed ID: 23155050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells.
    Coll ML; Rosen K; Ladeda V; Filmus J
    Oncogene; 2002 Apr; 21(18):2908-13. PubMed ID: 11973652
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1.
    Ihrlund LS; Hernlund E; Viktorsson K; Panaretakis T; Barna G; Sabapathy K; Linder S; Shoshan MC
    Exp Cell Res; 2006 May; 312(9):1581-9. PubMed ID: 16529740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased intestinal Bak expression results in apoptosis.
    Moss SF; Agarwal B; Arber N; Guan RJ; Krajewska M; Krajewski S; Reed JC; Holt PR
    Biochem Biophys Res Commun; 1996 Jun; 223(1):199-203. PubMed ID: 8660371
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas.
    Krajewska M; Moss SF; Krajewski S; Song K; Holt PR; Reed JC
    Cancer Res; 1996 May; 56(10):2422-7. PubMed ID: 8625322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.