BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 9846703)

  • 1. Prevention of antigen-induced microtubule organizing center reorientation in cytotoxic T cells by modulation of protein kinase C activity.
    Nesić D; Henderson S; Vukmanović S
    Int Immunol; 1998 Nov; 10(11):1741-6. PubMed ID: 9846703
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis.
    Radoja S; Saio M; Schaer D; Koneru M; Vukmanovic S; Frey AB
    J Immunol; 2001 Nov; 167(9):5042-51. PubMed ID: 11673513
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acidification is essential for maintaining the structure and function of lytic granules of CTL. Effect of concanamycin A, an inhibitor of vacuolar type H(+)-ATPase, on CTL-mediated cytotoxicity.
    Kataoka T; Takaku K; Magae J; Shinohara N; Takayama H; Kondo S; Nagai K
    J Immunol; 1994 Nov; 153(9):3938-47. PubMed ID: 7930604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.
    Kataoka T; Shinohara N; Takayama H; Takaku K; Kondo S; Yonehara S; Nagai K
    J Immunol; 1996 May; 156(10):3678-86. PubMed ID: 8621902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An anergic cytotoxic T lymphocyte clone exhibits granule exocytosis-mediated cytotoxicity.
    Kuwano K; Akashi A; Arai S
    Cell Immunol; 1998 May; 185(2):114-22. PubMed ID: 9636689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.
    Isaaz S; Baetz K; Olsen K; Podack E; Griffiths GM
    Eur J Immunol; 1995 Apr; 25(4):1071-9. PubMed ID: 7737276
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of lymphocyte-mediated cytolysis: functional cytolytic T cells lacking perforin and granzymes.
    Berke G; Rosen D; Ronen D
    Immunology; 1993 Jan; 78(1):105-12. PubMed ID: 8436395
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase Cdelta regulates antigen receptor-induced lytic granule polarization in mouse CD8+ CTL.
    Ma JS; Monu N; Shen DT; Mecklenbräuker I; Radoja N; Haydar TF; Leitges M; Frey AB; Vukmanovic S; Radoja S
    J Immunol; 2007 Jun; 178(12):7814-21. PubMed ID: 17548619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes.
    Trenn G; Takayama H; Sitkovsky MV
    Nature; 1987 Nov 5-11; 330(6143):72-4. PubMed ID: 3118213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Target cell-directed degradation of perforin mRNA in CTL: lack of correlation with loss of protein and lytic ability.
    Bochan M; Hommel-Berrey G; Brahmi Z
    Mol Immunol; 1994 Apr; 31(5):401-10. PubMed ID: 8152443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.
    Lowin B; Beermann F; Schmidt A; Tschopp J
    Proc Natl Acad Sci U S A; 1994 Nov; 91(24):11571-5. PubMed ID: 7972104
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of granule proteins in T-cell-mediated cytolysis.
    Krähenbühl O; Tschopp J
    Nat Immun Cell Growth Regul; 1990; 9(4):274-82. PubMed ID: 2215515
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic inhibition of human cell-mediated cytotoxicity by complement component antisera indicates that target cell lysis may result from an enzymatic cascade involving granzymes and perforin.
    Brahmi Z; Csipo I; Bochan MR; Su B; Montel AH; Morse PA
    Nat Immun; 1995 Sep; 14(5-6):271-85. PubMed ID: 8933821
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Highly lytic in vivo primed cytolytic T lymphocytes devoid of lytic granules and BLT-esterase activity acquire these constituents in the presence of T cell growth factors upon blast transformation in vitro.
    Berke G; Rosen D
    J Immunol; 1988 Sep; 141(5):1429-36. PubMed ID: 3261748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FD-891, a structural analogue of concanamycin A that does not affect vacuolar acidification or perforin activity, yet potently prevents cytotoxic T lymphocyte-mediated cytotoxicity through the blockage of conjugate formation.
    Kataoka T; Yamada A; Bando M; Honma T; Mizoue K; Nagai K
    Immunology; 2000 Jun; 100(2):170-7. PubMed ID: 10886392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Are lytic granules and perforin 1 involved in lysis induced by in vivo-primed peritoneal exudate cytolytic T lymphocytes?
    Berke G; Rosen D
    Transplant Proc; 1987 Feb; 19(1 Pt 1):412-6. PubMed ID: 3493559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and function of synaptotagmin VII in CTLs.
    Fowler KT; Andrews NW; Huleatt JW
    J Immunol; 2007 Feb; 178(3):1498-504. PubMed ID: 17237398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular and molecular mechanisms of activation of MHC nonrestricted cytotoxic cells by IL-12.
    Cesano A; Visonneau S; Clark SC; Santoli D
    J Immunol; 1993 Sep; 151(6):2943-57. PubMed ID: 8104216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role.
    Grybko MJ; Pores-Fernando AT; Wurth GA; Zweifach A
    J Leukoc Biol; 2007 Feb; 81(2):509-19. PubMed ID: 17077164
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of lysis by cytotoxic T lymphocyte clones. Lytic activity and gene expression in cloned antigen-specific CD4+ and CD8+ T lymphocytes.
    Lancki DW; Hsieh CS; Fitch FW
    J Immunol; 1991 May; 146(9):3242-9. PubMed ID: 1673149
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.