385 related articles for article (PubMed ID: 9850070)
1. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
[TBL] [Abstract][Full Text] [Related]
2. Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand.
Jiang JD; Denner L; Ling YH; Li JN; Davis A; Wang Y; Li Y; Roboz J; Wang LG; Perez-Soler R; Marcelli M; Bekesi G; Holland JF
Cancer Res; 2002 Nov; 62(21):6080-8. PubMed ID: 12414632
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of microtubule assembly in tumor cells by 3-bromoacetylamino benzoylurea, a new cancericidal compound.
Jiang JD; Wang Y; Roboz J; Strauchen J; Holland JF; Bekesi JG
Cancer Res; 1998 May; 58(10):2126-33. PubMed ID: 9605756
[TBL] [Abstract][Full Text] [Related]
4. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
[TBL] [Abstract][Full Text] [Related]
5. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
Gupta K; Bishop J; Peck A; Brown J; Wilson L; Panda D
Biochemistry; 2004 Jun; 43(21):6645-55. PubMed ID: 15157098
[TBL] [Abstract][Full Text] [Related]
6. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
[TBL] [Abstract][Full Text] [Related]
7. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
Chang JY; Chang CY; Kuo CC; Chen LT; Wein YS; Kuo YH
Mol Pharmacol; 2004 Jan; 65(1):77-84. PubMed ID: 14722239
[TBL] [Abstract][Full Text] [Related]
8. Bcl-xL is phosphorylated in malignant cells following microtubule disruption.
Poruchynsky MS; Wang EE; Rudin CM; Blagosklonny MV; Fojo T
Cancer Res; 1998 Aug; 58(15):3331-8. PubMed ID: 9699663
[TBL] [Abstract][Full Text] [Related]
9. Identification and characterization of A-105972, an antineoplastic agent.
Wu-Wong JR; Alder JD; Alder L; Burns DJ; Han EK; Credo B; Tahir SK; Dayton BD; Ewing PJ; Chiou WJ
Cancer Res; 2001 Feb; 61(4):1486-92. PubMed ID: 11245455
[TBL] [Abstract][Full Text] [Related]
10. Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.
Mulligan JM; Greene LM; Cloonan S; Mc Gee MM; Onnis V; Campiani G; Fattorusso C; Lawler M; Williams DC; Zisterer DM
Mol Pharmacol; 2006 Jul; 70(1):60-70. PubMed ID: 16571652
[TBL] [Abstract][Full Text] [Related]
11. Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin.
Kondoh M; Usui T; Nishikiori T; Mayumi T; Osada H
Biochem J; 1999 Jun; 340 ( Pt 2)(Pt 2):411-6. PubMed ID: 10333483
[TBL] [Abstract][Full Text] [Related]
12. Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole.
Mooberry SL; Weiderhold KN; Dakshanamurthy S; Hamel E; Banner EJ; Kharlamova A; Hempel J; Gupton JT; Brown ML
Mol Pharmacol; 2007 Jul; 72(1):132-40. PubMed ID: 17456786
[TBL] [Abstract][Full Text] [Related]
13. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
[TBL] [Abstract][Full Text] [Related]
14. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
Xiao D; Pinto JT; Soh JW; Deguchi A; Gundersen GG; Palazzo AF; Yoon JT; Shirin H; Weinstein IB
Cancer Res; 2003 Oct; 63(20):6825-37. PubMed ID: 14583480
[TBL] [Abstract][Full Text] [Related]
15. Induction of apoptosis in leukemic cells by the reversible microtubule-disrupting agent 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1 -one: protection by Bcl-2 and Bcl-X(L) and cell cycle arrest.
Gajate C; Barasoain I; Andreu JM; Mollinedo F
Cancer Res; 2000 May; 60(10):2651-9. PubMed ID: 10825137
[TBL] [Abstract][Full Text] [Related]
16. Taccalonolides E and A: Plant-derived steroids with microtubule-stabilizing activity.
Tinley TL; Randall-Hlubek DA; Leal RM; Jackson EM; Cessac JW; Quada JC; Hemscheidt TK; Mooberry SL
Cancer Res; 2003 Jun; 63(12):3211-20. PubMed ID: 12810650
[TBL] [Abstract][Full Text] [Related]
17. Loss of cell cycle control allows selective microtubule-active drug-induced Bcl-2 phosphorylation and cytotoxicity in autonomous cancer cells.
Blagosklonny MV; Bishop PC; Robey R; Fojo T; Bates SE
Cancer Res; 2000 Jul; 60(13):3425-8. PubMed ID: 10910051
[TBL] [Abstract][Full Text] [Related]
18. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
Bai R; Cichacz ZA; Herald CL; Pettit GR; Hamel E
Mol Pharmacol; 1993 Oct; 44(4):757-66. PubMed ID: 8232226
[TBL] [Abstract][Full Text] [Related]
19. Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.
Srivastava P; Panda D
FEBS J; 2007 Sep; 274(18):4788-801. PubMed ID: 17697112
[TBL] [Abstract][Full Text] [Related]
20. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY
J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]