373 related articles for article (PubMed ID: 9851974)
1. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice.
Holland EC; Hively WP; DePinho RA; Varmus HE
Genes Dev; 1998 Dec; 12(23):3675-85. PubMed ID: 9851974
[TBL] [Abstract][Full Text] [Related]
2. A mouse model for glioma: biology, pathology, and therapeutic opportunities.
Holland EC
Toxicol Pathol; 2000; 28(1):171-7. PubMed ID: 10669005
[TBL] [Abstract][Full Text] [Related]
3. Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.
Holland EC; Hively WP; Gallo V; Varmus HE
Genes Dev; 1998 Dec; 12(23):3644-9. PubMed ID: 9851971
[TBL] [Abstract][Full Text] [Related]
4. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo.
Dai C; Celestino JC; Okada Y; Louis DN; Fuller GN; Holland EC
Genes Dev; 2001 Aug; 15(15):1913-25. PubMed ID: 11485986
[TBL] [Abstract][Full Text] [Related]
5. Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.
Uhrbom L; Kastemar M; Johansson FK; Westermark B; Holland EC
Cancer Res; 2005 Mar; 65(6):2065-9. PubMed ID: 15781613
[TBL] [Abstract][Full Text] [Related]
6. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
Uhrbom L; Dai C; Celestino JC; Rosenblum MK; Fuller GN; Holland EC
Cancer Res; 2002 Oct; 62(19):5551-8. PubMed ID: 12359767
[TBL] [Abstract][Full Text] [Related]
7. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Bachoo RM; Maher EA; Ligon KL; Sharpless NE; Chan SS; You MJ; Tang Y; DeFrances J; Stover E; Weissleder R; Rowitch DH; Louis DN; DePinho RA
Cancer Cell; 2002 Apr; 1(3):269-77. PubMed ID: 12086863
[TBL] [Abstract][Full Text] [Related]
8. Investigation of germline PTEN, p53, p16(INK4A)/p14(ARF), and CDK4 alterations in familial glioma.
Tachibana I; Smith JS; Sato K; Hosek SM; Kimmel DW; Jenkins RB
Am J Med Genet; 2000 May; 92(2):136-41. PubMed ID: 10797439
[TBL] [Abstract][Full Text] [Related]
9. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
D'Amico M; Wu K; Di Vizio D; Reutens AT; Stahl M; Fu M; Albanese C; Russell RG; Muller WJ; White M; Negassa A; Lee HW; DePinho RA; Pestell RG
Cancer Res; 2003 Jun; 63(12):3395-402. PubMed ID: 12810676
[TBL] [Abstract][Full Text] [Related]
10. Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo.
Huang ZY; Baldwin RL; Hedrick NM; Gutmann DH
Oncogene; 2002 Feb; 21(9):1325-34. PubMed ID: 11857076
[TBL] [Abstract][Full Text] [Related]
11. p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice.
Shank-Calvo JA; Draheim K; Bhasin M; Kelliher MA
Oncogene; 2006 May; 25(21):3023-31. PubMed ID: 16407836
[TBL] [Abstract][Full Text] [Related]
12. p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma.
Fulci G; Labuhn M; Maier D; Lachat Y; Hausmann O; Hegi ME; Janzer RC; Merlo A; Van Meir EG
Oncogene; 2000 Aug; 19(33):3816-22. PubMed ID: 10949938
[TBL] [Abstract][Full Text] [Related]
13. Lack of germ-line mutations of CDK4, p16(INK4A), and p15(INK4B) in families with glioma.
Gao L; Liu L; van Meyel D; Cairncross G; Forsyth P; Kimmel D; Jenkins RB; Lassam NJ; Hogg D
Clin Cancer Res; 1997 Jun; 3(6):977-81. PubMed ID: 9815774
[TBL] [Abstract][Full Text] [Related]
14. Growth inhibitory effect on glioma cells of adenovirus-mediated p16/INK4a gene transfer in vitro and in vivo.
Lee SH; Kim MS; Kwon HC; Park IC; Park MJ; Lee CT; Kim YW; Kim CM; Hong SI
Int J Mol Med; 2000 Nov; 6(5):559-63. PubMed ID: 11029524
[TBL] [Abstract][Full Text] [Related]
15. Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
Ding H; Shannon P; Lau N; Wu X; Roncari L; Baldwin RL; Takebayashi H; Nagy A; Gutmann DH; Guha A
Cancer Res; 2003 Mar; 63(5):1106-13. PubMed ID: 12615729
[TBL] [Abstract][Full Text] [Related]
16. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
[TBL] [Abstract][Full Text] [Related]
17. Establishment and partial characterization of five malignant glioma cell lines.
Zhang L; Yamane T; Satoh E; Amagasaki K; Kawataki T; Asahara T; Furuya K; Nukui H; Naganuma H
Neuropathology; 2005 Jun; 25(2):136-43. PubMed ID: 15875906
[TBL] [Abstract][Full Text] [Related]
18. p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation.
Radfar A; Unnikrishnan I; Lee HW; DePinho RA; Rosenberg N
Proc Natl Acad Sci U S A; 1998 Oct; 95(22):13194-9. PubMed ID: 9789064
[TBL] [Abstract][Full Text] [Related]
19. The early growth response gene EGR-1 behaves as a suppressor gene that is down-regulated independent of ARF/Mdm2 but not p53 alterations in fresh human gliomas.
Calogero A; Arcella A; De Gregorio G; Porcellini A; Mercola D; Liu C; Lombari V; Zani M; Giannini G; Gagliardi FM; Caruso R; Gulino A; Frati L; Ragona G
Clin Cancer Res; 2001 Sep; 7(9):2788-96. PubMed ID: 11555594
[TBL] [Abstract][Full Text] [Related]
20. Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas.
Labuhn M; Jones G; Speel EJ; Maier D; Zweifel C; Gratzl O; Van Meir EG; Hegi ME; Merlo A
Oncogene; 2001 Mar; 20(9):1103-9. PubMed ID: 11314047
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
