BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 9852077)

  • 1. Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.
    Chen PF; Berka V; Tsai AL; Wu KK
    J Biol Chem; 1998 Dec; 273(51):34164-70. PubMed ID: 9852077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.
    Chen PF; Berka V; Wu KK
    Arch Biochem Biophys; 2003 Mar; 411(1):83-92. PubMed ID: 12590926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.
    Martásek P; Miller RT; Liu Q; Roman LJ; Salerno JC; Migita CT; Raman CS; Gross SS; Ikeda-Saito M; Masters BS
    J Biol Chem; 1998 Dec; 273(52):34799-805. PubMed ID: 9857005
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH.
    Sagami I; Sato Y; Daff S; Shimizu T
    J Biol Chem; 2000 Aug; 275(34):26150-7. PubMed ID: 10846172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endothelial nitric oxide synthase: modulations of the distal heme site produced by progressive N-terminal deletions.
    Rodríguez-Crespo I; Moënne-Loccoz P; Loehr TM; Ortiz de Montellano PR
    Biochemistry; 1997 Jul; 36(28):8530-8. PubMed ID: 9214298
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of key residues in the subdomain encoded by exons 8 and 9 of human inducible nitric oxide synthase: a critical role for Asp-280 in substrate binding and subunit interactions.
    Ghosh DK; Rashid MB; Crane B; Taskar V; Mast M; Misukonis MA; Weinberg JB; Eissa NT
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10392-7. PubMed ID: 11517317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of the remote heme site geometry of recombinant mouse neuronal nitric-oxide synthase by the N-terminal hook region.
    Iwasaki T; Hori H; Hayashi Y; Nishino T
    J Biol Chem; 1999 Mar; 274(12):7705-13. PubMed ID: 10075660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study.
    Sagami I; Shimizu T
    J Biol Chem; 1998 Jan; 273(4):2105-8. PubMed ID: 9442050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase.
    Abu-Soud HM; Ichimori K; Presta A; Stuehr DJ
    J Biol Chem; 2000 Jun; 275(23):17349-57. PubMed ID: 10749853
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer.
    Daff S; Sagami I; Shimizu T
    J Biol Chem; 1999 Oct; 274(43):30589-95. PubMed ID: 10521442
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stopped-flow analysis of CO and NO binding to inducible nitric oxide synthase.
    Abu-Soud HM; Wu C; Ghosh DK; Stuehr DJ
    Biochemistry; 1998 Mar; 37(11):3777-86. PubMed ID: 9521697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of the heme proximal side residues tryptophan409 and tryptophan421 of neuronal nitric oxide synthase in the electron transfer reaction.
    Yumoto T; Sagami I; Daff S; Shimizu T
    J Inorg Biochem; 2000 Nov; 82(1-4):163-70. PubMed ID: 11132623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.
    Rodríguez-Crespo I; Gerber NC; Ortiz de Montellano PR
    J Biol Chem; 1996 May; 271(19):11462-7. PubMed ID: 8626704
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction.
    Ghosh DK; Crane BR; Ghosh S; Wolan D; Gachhui R; Crooks C; Presta A; Tainer JA; Getzoff ED; Stuehr DJ
    EMBO J; 1999 Nov; 18(22):6260-70. PubMed ID: 10562538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding.
    Gachhui R; Ghosh DK; Wu C; Parkinson J; Crane BR; Stuehr DJ
    Biochemistry; 1997 Apr; 36(17):5097-103. PubMed ID: 9136868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.
    Wang ZQ; Wei CC; Santolini J; Panda K; Wang Q; Stuehr DJ
    Biochemistry; 2005 Mar; 44(12):4676-90. PubMed ID: 15779894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Low-temperature optical absorption spectra suggest a redox role for tetrahydrobiopterin in both steps of nitric oxide synthase catalysis.
    Gorren AC; Bec N; Schrammel A; Werner ER; Lange R; Mayer B
    Biochemistry; 2000 Sep; 39(38):11763-70. PubMed ID: 10995244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity.
    Chen PF; Tsai AL; Wu KK
    Biochem Biophys Res Commun; 1995 Oct; 215(3):1119-29. PubMed ID: 7488039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation of the five conserved histidines in the endothelial nitric-oxide synthase hemoprotein domain. No evidence for a non-heme metal requirement for catalysis.
    Rodríguez-Crespo I; Nishida CR; Knudsen GM; de Montellano PR
    J Biol Chem; 1999 Jul; 274(31):21617-24. PubMed ID: 10419469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase.
    Wei CC; Wang ZQ; Wang Q; Meade AL; Hemann C; Hille R; Stuehr DJ
    J Biol Chem; 2001 Jan; 276(1):315-9. PubMed ID: 11020389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.