BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 9855641)

  • 1. Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element.
    Schuetz EG; Brimer C; Schuetz JD
    Mol Pharmacol; 1998 Dec; 54(6):1113-7. PubMed ID: 9855641
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors.
    Huss JM; Kasper CB
    Mol Pharmacol; 2000 Jul; 58(1):48-57. PubMed ID: 10860926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
    LeCluyse EL
    Chem Biol Interact; 2001 May; 134(3):283-9. PubMed ID: 11336976
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.
    Ma Y; Sachdeva K; Liu J; Song X; Li Y; Yang D; Deng R; Chichester CO; Yan B
    Biochem Pharmacol; 2005 May; 69(9):1363-71. PubMed ID: 15826607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter.
    Song X; Li Y; Liu J; Mukundan M; Yan B
    J Pharmacol Exp Ther; 2005 Feb; 312(2):571-82. PubMed ID: 15367577
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23.
    Shi D; Yang D; Yan B
    Biochem Pharmacol; 2010 Oct; 80(8):1274-83. PubMed ID: 20599767
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
    J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
    Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
    Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
    Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pregnane X receptor-dependent and -independent effects of 2-acetylaminofluorene on cytochrome P450 3A23 expression and liver cell proliferation.
    Sparfel L; Payen L; Gilot D; Sidaway J; Morel F; Guillouzo A; Fardel O
    Biochem Biophys Res Commun; 2003 Jan; 300(2):278-84. PubMed ID: 12504080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of intrauterine undernutrition on the expression of CYP3A23/3A1, PXR, CAR and HNF4alpha in neonate rats.
    Ni S; Wang X; Wang J; Lu S; Zeng S; Zhao Z; Yu L; Chen S
    Biopharm Drug Dispos; 2008 Dec; 29(9):501-10. PubMed ID: 19058292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endocrine disrupting chemicals, phthalic acid and nonylphenol, activate Pregnane X receptor-mediated transcription.
    Masuyama H; Hiramatsu Y; Kunitomi M; Kudo T; MacDonald PN
    Mol Endocrinol; 2000 Mar; 14(3):421-8. PubMed ID: 10707959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
    Ripp SL; Fitzpatrick JL; Peters JM; Prough RA
    Drug Metab Dispos; 2002 May; 30(5):570-5. PubMed ID: 11950789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
    Jones SA; Moore LB; Shenk JL; Wisely GB; Hamilton GA; McKee DD; Tomkinson NC; LeCluyse EL; Lambert MH; Willson TM; Kliewer SA; Moore JT
    Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
    Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.
    Kliewer SA; Moore JT; Wade L; Staudinger JL; Watson MA; Jones SA; McKee DD; Oliver BB; Willson TM; Zetterström RH; Perlmann T; Lehmann JM
    Cell; 1998 Jan; 92(1):73-82. PubMed ID: 9489701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The expression of pregnane X receptor and its target gene, cytochrome P450 3A1, in perinatal mouse.
    Masuyama H; Hiramatsu Y; Mizutani Y; Inoshita H; Kudo T
    Mol Cell Endocrinol; 2001 Feb; 172(1-2):47-56. PubMed ID: 11165039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.
    Gährs M; Roos R; Andersson PL; Schrenk D
    Toxicol Appl Pharmacol; 2013 Oct; 272(1):77-85. PubMed ID: 23770461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.