111 related articles for article (PubMed ID: 9860824)
1. Approaching the transition state in the crystal structure of a phosphoribosyltransferase.
Focia PJ; Craig SP; Eakin AE
Biochemistry; 1998 Dec; 37(49):17120-7. PubMed ID: 9860824
[TBL] [Abstract][Full Text] [Related]
2. A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.
Focia PJ; Craig SP; Nieves-Alicea R; Fletterick RJ; Eakin AE
Biochemistry; 1998 Oct; 37(43):15066-75. PubMed ID: 9790669
[TBL] [Abstract][Full Text] [Related]
3. The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
Keough DT; Brereton IM; de Jersey J; Guddat LW
J Mol Biol; 2005 Aug; 351(1):170-81. PubMed ID: 15990111
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of the dimeric phosphoenolpyruvate carboxykinase (PEPCK) from Trypanosoma cruzi at 2 A resolution.
Trapani S; Linss J; Goldenberg S; Fischer H; Craievich AF; Oliva G
J Mol Biol; 2001 Nov; 313(5):1059-72. PubMed ID: 11700062
[TBL] [Abstract][Full Text] [Related]
5. Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding.
Balendiran GK; Molina JA; Xu Y; Torres-Martinez J; Stevens R; Focia PJ; Eakin AE; Sacchettini JC; Craig SP
Protein Sci; 1999 May; 8(5):1023-31. PubMed ID: 10338013
[TBL] [Abstract][Full Text] [Related]
6. Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.
Freymann DM; Wenck MA; Engel JC; Feng J; Focia PJ; Eakin AE; Craig SP
Chem Biol; 2000 Dec; 7(12):957-68. PubMed ID: 11137818
[TBL] [Abstract][Full Text] [Related]
7. Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1.
Welin M; Egeblad L; Johansson A; Stenmark P; Wang L; Flodin S; Nyman T; Trésaugues L; Kotenyova T; Johansson I; Eriksson S; Eklund H; Nordlund P
FEBS J; 2010 Dec; 277(23):4920-30. PubMed ID: 21054786
[TBL] [Abstract][Full Text] [Related]
8. Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase.
González-Segura L; Witte JF; McClard RW; Hurley TD
Biochemistry; 2007 Dec; 46(49):14075-86. PubMed ID: 18020427
[TBL] [Abstract][Full Text] [Related]
9. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.
Héroux A; White EL; Ross LJ; Kuzin AP; Borhani DW
Structure; 2000 Dec; 8(12):1309-18. PubMed ID: 11188695
[TBL] [Abstract][Full Text] [Related]
10. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
Senkovich O; Schormann N; Chattopadhyay D
Acta Crystallogr D Biol Crystallogr; 2009 Jul; 65(Pt 7):704-16. PubMed ID: 19564691
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
Gayathri P; Sujay Subbayya IN; Ashok CS; Selvi TS; Balaram H; Murthy MR
Proteins; 2008 Dec; 73(4):1010-20. PubMed ID: 18536021
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.
Héroux A; White EL; Ross LJ; Davis RL; Borhani DW
Biochemistry; 1999 Nov; 38(44):14495-506. PubMed ID: 10545171
[TBL] [Abstract][Full Text] [Related]
13. Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.
Butterworth AC; Medrano FJ; Eakin AE; Craig SP
Biochim Biophys Acta; 2004 Jun; 1699(1-2):87-94. PubMed ID: 15158715
[TBL] [Abstract][Full Text] [Related]
14. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
Somoza JR; Chin MS; Focia PJ; Wang CC; Fletterick RJ
Biochemistry; 1996 Jun; 35(22):7032-40. PubMed ID: 8679528
[TBL] [Abstract][Full Text] [Related]
15. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Shi W; Li CM; Tyler PC; Furneaux RH; Cahill SM; Girvin ME; Grubmeyer C; Schramm VL; Almo SC
Biochemistry; 1999 Aug; 38(31):9872-80. PubMed ID: 10433693
[TBL] [Abstract][Full Text] [Related]
16. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
Chen Q; Liang Y; Su X; Gu X; Zheng X; Luo M
J Mol Biol; 2005 May; 348(5):1199-210. PubMed ID: 15854655
[TBL] [Abstract][Full Text] [Related]
17. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
[TBL] [Abstract][Full Text] [Related]
18. Conformational flexibility of PEP mutase.
Liu S; Lu Z; Han Y; Jia Y; Howard A; Dunaway-Mariano D; Herzberg O
Biochemistry; 2004 Apr; 43(15):4447-53. PubMed ID: 15078090
[TBL] [Abstract][Full Text] [Related]
19. Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase.
Lee CC; Medrano FJ; Craig SP; Eakin AE
Biochim Biophys Acta; 2001 Jul; 1537(1):63-70. PubMed ID: 11476964
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
Tebbe J; Bzowska A; Wielgus-Kutrowska B; Schröder W; Kazimierczuk Z; Shugar D; Saenger W; Koellner G
J Mol Biol; 1999 Dec; 294(5):1239-55. PubMed ID: 10600382
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]