180 related articles for article (PubMed ID: 9860973)
1. Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells.
Suzuki N; Urano J; Tamanoi F
Proc Natl Acad Sci U S A; 1998 Dec; 95(26):15356-61. PubMed ID: 9860973
[TBL] [Abstract][Full Text] [Related]
2. Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents.
Suzuki N; Del Villar K; Tamanoi F
Proc Natl Acad Sci U S A; 1998 Sep; 95(18):10499-504. PubMed ID: 9724732
[TBL] [Abstract][Full Text] [Related]
3. Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines.
Edamatsu H; Gau CL; Nemoto T; Guo L; Tamanoi F
Oncogene; 2000 Jun; 19(27):3059-68. PubMed ID: 10871858
[TBL] [Abstract][Full Text] [Related]
4. Involvement of nitric oxide in farnesyltransferase inhibitor-mediated apoptosis in chronic myeloid leukemia cells.
Selleri C; Maciejewski JP; Montuori N; Ricci P; Visconte V; Serio B; Luciano L; Rotoli B
Blood; 2003 Aug; 102(4):1490-8. PubMed ID: 12714496
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
Lobell RB; Omer CA; Abrams MT; Bhimnathwala HG; Brucker MJ; Buser CA; Davide JP; deSolms SJ; Dinsmore CJ; Ellis-Hutchings MS; Kral AM; Liu D; Lumma WC; Machotka SV; Rands E; Williams TM; Graham SL; Hartman GD; Oliff AI; Heimbrook DC; Kohl NE
Cancer Res; 2001 Dec; 61(24):8758-68. PubMed ID: 11751396
[TBL] [Abstract][Full Text] [Related]
6. Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.
Brassard DL; English JM; Malkowski M; Kirschmeier P; Nagabhushan TL; Bishop WR
Exp Cell Res; 2002 Feb; 273(2):138-46. PubMed ID: 11822869
[TBL] [Abstract][Full Text] [Related]
7. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.
Marzo I; Pérez-Galán P; Giraldo P; López-Royuela N; Gómez-Benito M; Larrad L; Lasierra P; Rubio-Félix D; Anel A; Naval J
Leukemia; 2004 Oct; 18(10):1599-604. PubMed ID: 15356656
[TBL] [Abstract][Full Text] [Related]
8. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
Gómez-Benito M; Marzo I; Anel A; Naval J
Mol Pharmacol; 2005 Jun; 67(6):1991-8. PubMed ID: 15738311
[TBL] [Abstract][Full Text] [Related]
9. The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.
Jiang K; Coppola D; Crespo NC; Nicosia SV; Hamilton AD; Sebti SM; Cheng JQ
Mol Cell Biol; 2000 Jan; 20(1):139-48. PubMed ID: 10594016
[TBL] [Abstract][Full Text] [Related]
10. Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.
Du W; Lebowitz PF; Prendergast GC
Mol Cell Biol; 1999 Mar; 19(3):1831-40. PubMed ID: 10022870
[TBL] [Abstract][Full Text] [Related]
11. c-myc down-regulation induces apoptosis in human cancer cell lines exposed to RPR-115135 (C31H29NO4), a non-peptidomimetic farnesyltransferase inhibitor.
Russo P; Arzani D; Trombino S; Falugi C
J Pharmacol Exp Ther; 2003 Jan; 304(1):37-47. PubMed ID: 12490573
[TBL] [Abstract][Full Text] [Related]
12. Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
Hirpara JL; Seyed MA; Loh KW; Dong H; Kini RM; Pervaiz S
Blood; 2000 Mar; 95(5):1773-80. PubMed ID: 10688837
[TBL] [Abstract][Full Text] [Related]
13. The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells.
Bolick SC; Landowski TH; Boulware D; Oshiro MM; Ohkanda J; Hamilton AD; Sebti SM; Dalton WS
Leukemia; 2003 Feb; 17(2):451-7. PubMed ID: 12592346
[TBL] [Abstract][Full Text] [Related]
14. Manumycin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells.
Frassanito MA; Cusmai A; Piccoli C; Dammacco F
Br J Haematol; 2002 Jul; 118(1):157-65. PubMed ID: 12100143
[TBL] [Abstract][Full Text] [Related]
15. Vibrio vulnificus cytolysin induces superoxide anion-initiated apoptotic signaling pathway in human ECV304 cells.
Kwon KB; Yang JY; Ryu DG; Rho HW; Kim JS; Park JW; Kim HR; Park BH
J Biol Chem; 2001 Dec; 276(50):47518-23. PubMed ID: 11591724
[TBL] [Abstract][Full Text] [Related]
16. Activation of caspase-2 mediates the apoptosis induced by GTP-depletion in insulin-secreting (HIT-T15) cells.
Huo J; Luo RH; Metz SA; Li G
Endocrinology; 2002 May; 143(5):1695-704. PubMed ID: 11956151
[TBL] [Abstract][Full Text] [Related]
17. Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.
Pan MH; Chang WL; Lin-Shiau SY; Ho CT; Lin JK
J Agric Food Chem; 2001 Mar; 49(3):1464-74. PubMed ID: 11312881
[TBL] [Abstract][Full Text] [Related]
18. Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release.
Zhang Y; Bhavnani BR
BMC Neurosci; 2005 Feb; 6():13. PubMed ID: 15730564
[TBL] [Abstract][Full Text] [Related]
19. Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells.
Kwon SH; Ahn SH; Kim YK; Bae GU; Yoon JW; Hong S; Lee HY; Lee YW; Lee HW; Han JW
J Biol Chem; 2002 Jan; 277(3):2073-80. PubMed ID: 11698395
[TBL] [Abstract][Full Text] [Related]
20. Antimycin A-induced killing of HL-60 cells: apoptosis initiated from within mitochondria does not necessarily proceed via caspase 9.
King MA
Cytometry A; 2005 Feb; 63(2):69-76. PubMed ID: 15655802
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
