BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 9864090)

  • 1. Use of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing.
    van Steeg H; Klein H; Beems RB; van Kreijl CF
    Toxicol Pathol; 1998; 26(6):742-9. PubMed ID: 9864090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models.
    van Steeg H; de Vries A; van Oostrom CTh ; van Benthem J; Beems RB; van Kreijl CF
    Toxicol Pathol; 2001; 29 Suppl():109-16. PubMed ID: 11695546
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Xpa and Xpa/p53+/- knockout mice: overview of available data.
    van Kreijl CF; McAnulty PA; Beems RB; Vynckier A; van Steeg H; Fransson-Steen R; Alden CL; Forster R; van der Laan JW; Vandenberghe J
    Toxicol Pathol; 2001; 29 Suppl():117-27. PubMed ID: 11695547
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol.
    Lina BA; Woutersen RA; Bruijntjes JP; van Benthem J; van den Berg JA; Monbaliu J; Thoolen BJ; Beems RB; van Kreijl CF
    Toxicol Pathol; 2004; 32(2):192-201. PubMed ID: 15200157
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mice deficient in the nucleotide excision repair gene XPA have elevated sensitivity to benzo[a]pyrene induction of lung tumors.
    Ide F; Iida N; Nakatsuru Y; Oda H; Tanaka K; Ishikawa T
    Carcinogenesis; 2000 Jun; 21(6):1263-5. PubMed ID: 10837020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spontaneous liver tumors and benzo[a]pyrene-induced lymphomas in XPA-deficient mice.
    de Vries A; van Oostrom CT; Dortant PM; Beems RB; van Kreijl CF; Capel PJ; van Steeg H
    Mol Carcinog; 1997 May; 19(1):46-53. PubMed ID: 9180928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of DNA adducts and mutations in spleen, liver and lung of XPA-deficient/lacZ transgenic mice after oral treatment with benzo[a]pyrene: correlation with tumour development.
    de Vries A; Dollé ME; Broekhof JL; Muller JJ; Kroese ED; van Kreijl CF; Capel PJ; Vijg J; van Steeg H
    Carcinogenesis; 1997 Dec; 18(12):2327-32. PubMed ID: 9450477
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
    van Kesteren PC; Zwart PE; Pennings JL; Gottschalk WH; Kleinjans JC; van Delft JH; van Steeg H; Luijten M
    Toxicol Sci; 2011 Sep; 123(1):123-32. PubMed ID: 21715664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice.
    van Steeg H; Mullenders LH; Vijg J
    Mutat Res; 2000 May; 450(1-2):167-80. PubMed ID: 10838141
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl-imidazo [4,5-b] pyridine (PhIP).
    Imaida K; Ogawa K; Takahashi S; Ito T; Yamaguchi T; Totsuka Y; Wakabayashi K; Tanaka K; Ito N; Shirai T
    Cancer Lett; 2000 Mar; 150(1):63-9. PubMed ID: 10755388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
    Hoogervorst EM; van Oostrom CT; Beems RB; van Benthem J; Gielis S; Vermeulen JP; Wester PW; Vos JG; de Vries A; van Steeg H
    Cancer Res; 2004 Aug; 64(15):5118-26. PubMed ID: 15289314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.
    de Vries A; van Oostrom CT; Hofhuis FM; Dortant PM; Berg RJ; de Gruijl FR; Wester PW; van Kreijl CF; Capel PJ; van Steeg H; Verbeek SJ
    Nature; 1995 Sep; 377(6545):169-73. PubMed ID: 7675086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice.
    van Oostrom CT; Boeve M; van Den Berg J; de Vries A; Dollé ME; Beems RB; van Kreijl CF; Vijg J; van Steeg H
    Environ Mol Mutagen; 1999; 34(2-3):124-30. PubMed ID: 10529736
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intestinal toxicity and carcinogenic potential of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in DNA repair deficient XPA-/- mice.
    Klein JC; Beems RB; Zwart PE; Hamzink M; Zomer G; van Steeg H; van Kreijl CF
    Carcinogenesis; 2001 Apr; 22(4):619-26. PubMed ID: 11285198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UV-induced skin carcinogenesis in xeroderma pigmentosum group A (XPA) gene-knockout mice with nucleotide excision repair-deficiency.
    Tanaka K; Kamiuchi S; Ren Y; Yonemasu R; Ichikawa M; Murai H; Yoshino M; Takeuchi S; Saijo M; Nakatsu Y; Miyauchi-Hashimoto H; Horio T
    Mutat Res; 2001 Jun; 477(1-2):31-40. PubMed ID: 11376684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
    de Vries A; Berg RJ; Wijnhoven S; Westerman A; Wester PW; van Kreijl CF; Capel PJ; de Gruijl FR; van Kranen HJ; van Steeg H
    Oncogene; 1998 Apr; 16(17):2205-12. PubMed ID: 9619829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies of in vivo mutations in rpsL transgene in UVB-irradiated epidermis of XPA-deficient mice.
    Murai H; Takeuchi S; Nakatsu Y; Ichikawa M; Yoshino M; Gondo Y; Katsuki M; Tanaka K
    Mutat Res; 2000 May; 450(1-2):181-92. PubMed ID: 10838142
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.
    Boonstra A; van Oudenaren A; Baert M; van Steeg H; Leenen PJ; van der Horst GT; Hoeijmakers JH; Savelkoul HF; Garssen J
    J Invest Dermatol; 2001 Jul; 117(1):141-6. PubMed ID: 11442761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of nucleotide excision repair deficiency in intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice.
    Steffensen IL; Schut HA; Nesland JM; Tanaka K; Alexander J
    Mutat Res; 2006 Dec; 611(1-2):71-82. PubMed ID: 16962818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carcinogen-induced inflammation and immunosuppression are enhanced in xeroderma pigmentosum group A model mice associated with hyperproduction of prostaglandin E2.
    Miyauchi-Hashimoto H; Kuwamoto K; Urade Y; Tanaka K; Horio T
    J Immunol; 2001 May; 166(9):5782-91. PubMed ID: 11313422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.