133 related articles for article (PubMed ID: 9867659)
1. Outsmarting HIV drug resistance.
Balter M
Science; 1998 Nov; 282(5394):1623, 1625. PubMed ID: 9867659
[No Abstract] [Full Text] [Related]
2. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
[TBL] [Abstract][Full Text] [Related]
3. Understanding the basis of resistance in the irksome Lys103Asn HIV-1 reverse transcriptase mutant through targeted molecular dynamics simulations.
Rodríguez-Barrios F; Gago F
J Am Chem Soc; 2004 Dec; 126(47):15386-7. PubMed ID: 15563158
[TBL] [Abstract][Full Text] [Related]
4. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance.
Huang H; Chopra R; Verdine GL; Harrison SC
Science; 1998 Nov; 282(5394):1669-75. PubMed ID: 9831551
[TBL] [Abstract][Full Text] [Related]
5. Closing in on HIV drug resistance.
Larder BA; Stammers DK
Nat Struct Biol; 1999 Feb; 6(2):103-6. PubMed ID: 10048915
[No Abstract] [Full Text] [Related]
6. Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates.
Quan Y; Gu Z; Li X; Liang C; Parniak MA; Wainberg MA
J Mol Biol; 1998 Mar; 277(2):237-47. PubMed ID: 9514745
[TBL] [Abstract][Full Text] [Related]
7. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
Hopkins AL; Ren J; Milton J; Hazen RJ; Chan JH; Stuart DI; Stammers DK
J Med Chem; 2004 Nov; 47(24):5912-22. PubMed ID: 15537346
[TBL] [Abstract][Full Text] [Related]
8. Nucleotide analogue binding, catalysis and primer unblocking in the mechanisms of HIV-1 reverse transcriptase-mediated resistance to nucleoside analogues.
Selmi B; Deval J; Boretto J; Canard B
Antivir Ther; 2003 Apr; 8(2):143-54. PubMed ID: 12741627
[TBL] [Abstract][Full Text] [Related]
9. Reverse transcriptase fidelity and HIV-1 variation.
Keulen W; Nijhuis M; Schuurman R; Berkhout B; Boucher C
Science; 1997 Jan; 275(5297):229; author reply 230-1. PubMed ID: 8999550
[No Abstract] [Full Text] [Related]
10. Docking of non-nucleoside inhibitors: neotripterifordin and its derivatives to HIV-1 reverse transcriptase.
Zhou Z; Madrid M; Madura JD
Proteins; 2002 Dec; 49(4):529-42. PubMed ID: 12402361
[TBL] [Abstract][Full Text] [Related]
11. Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.
Ren J; Nichols CE; Chamberlain PP; Weaver KL; Short SA; Stammers DK
J Mol Biol; 2004 Feb; 336(3):569-78. PubMed ID: 15095972
[TBL] [Abstract][Full Text] [Related]
12. Rational approaches for the design of effective human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitors.
Ribone SR; Quevedo MA; Madrid M; Briñón MC
J Chem Inf Model; 2011 Jan; 51(1):130-8. PubMed ID: 21133347
[TBL] [Abstract][Full Text] [Related]
13. Combined approach using ligand efficiency, cross-docking, and antitarget hits for wild-type and drug-resistant Y181C HIV-1 reverse transcriptase.
García-Sosa AT; Sild S; Takkis K; Maran U
J Chem Inf Model; 2011 Oct; 51(10):2595-611. PubMed ID: 21875140
[TBL] [Abstract][Full Text] [Related]
14. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
15. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
16. Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1.
Chan JH; Freeman GA; Tidwell JH; Romines KR; Schaller LT; Cowan JR; Gonzales SS; Lowell GS; Andrews CW; Reynolds DJ; St Clair M; Hazen RJ; Ferris RG; Creech KL; Roberts GB; Short SA; Weaver K; Koszalka GW; Boone LR
J Med Chem; 2004 Feb; 47(5):1175-82. PubMed ID: 14971897
[TBL] [Abstract][Full Text] [Related]
17. Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
Kisic M; Mendieta J; Puertas MC; Parera M; Martínez MA; Martinez-Picado J; Menéndez-Arias L
J Mol Biol; 2008 Oct; 382(2):327-41. PubMed ID: 18662701
[TBL] [Abstract][Full Text] [Related]
18. A pharmacophore docking algorithm and its application to the cross-docking of 18 HIV-NNRTI's in their binding pockets.
Daeyaert F; de Jonge M; Heeres J; Koymans L; Lewi P; Vinkers MH; Janssen PA
Proteins; 2004 Feb; 54(3):526-33. PubMed ID: 14748000
[TBL] [Abstract][Full Text] [Related]
19. Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
Ren J; Nichols CE; Stamp A; Chamberlain PP; Ferris R; Weaver KL; Short SA; Stammers DK
FEBS J; 2006 Aug; 273(16):3850-60. PubMed ID: 16911530
[TBL] [Abstract][Full Text] [Related]
20. Effect of a bound non-nucleoside RT inhibitor on the dynamics of wild-type and mutant HIV-1 reverse transcriptase.
Zhou Z; Madrid M; Evanseck JD; Madura JD
J Am Chem Soc; 2005 Dec; 127(49):17253-60. PubMed ID: 16332074
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
