These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 9871691)

  • 1. Heteroatom-substitution as a strategy for increasing the potency of competitive NMDA antagonists.
    Ornstein PL; Arnold MB; Lunn WH; Heinz LJ; Leander JD; Lodge D; Schoepp DD
    Bioorg Med Chem Lett; 1998 Feb; 8(4):389-94. PubMed ID: 9871691
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.
    Schoepp DD; Ornstein PL; Leander JD; Lodge D; Salhoff CR; Zeman S; Zimmerman DM
    J Pharmacol Exp Ther; 1990 Dec; 255(3):1301-8. PubMed ID: 2148188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.
    Ornstein PL; Schoepp DD; Arnold MB; Leander JD; Lodge D; Paschal JW; Elzey T
    J Med Chem; 1991 Jan; 34(1):90-7. PubMed ID: 1825117
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist.
    Ornstein PL; Schoepp DD; Leander JD; Wong T; Zimmerman DM; Lodge D
    Prog Clin Biol Res; 1990; 361():429-33. PubMed ID: 2149764
    [No Abstract]   [Full Text] [Related]  

  • 5. Synthesis, preliminary evaluation and molecular modeling studies of new, conformationally constrained analogues of the competitive NMDA receptor antagonist 4-(phosphonomethyl)-2-piperidinecarboxylic acid (CGS 19755).
    Pellicciari R; Marinozzi M; Natalini B; Costantino G; Lankin DC; Snyder JP; Monahan JB
    Farmaco; 1997; 52(6-7):477-86. PubMed ID: 9490080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NMDA antagonist activity of (+/-)-(2SR,4RS)-4-(1H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer.
    Ornstein PL; Schoepp DD; Arnold MB; Jones ND; Deeter JB; Lodge D; Leander JD
    J Med Chem; 1992 Aug; 35(17):3111-5. PubMed ID: 1387167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of C5-tetrazole derivatives of 2-amino-adipic acid displaying NMDA glutamate receptor antagonism.
    Lenda F; Crouzin N; Cavalier M; Guiramand J; Lanté F; Barbanel G; Cohen-Solal C; Martinez J; Guenoun F; Lamaty F; Vignes M
    Amino Acids; 2011 Mar; 40(3):913-22. PubMed ID: 20706748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Borowicz KK; Gasior M; Kleinrok Z; Czuczwar SJ
    Epilepsia; 1996 Jul; 37(7):618-24. PubMed ID: 8681893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]- quinoxaline-2,3-dione and related quinoxalinediones: characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity.
    Bigge CF; Malone TC; Boxer PA; Nelson CB; Ortwine DF; Schelkun RM; Retz DM; Lescosky LJ; Borosky SA; Vartanian MG
    J Med Chem; 1995 Sep; 38(19):3720-40. PubMed ID: 7562904
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protective use of N-methyl-D-aspartate receptor antagonists as a spinoplegia against excitatory amino acid neurotoxicity.
    Cho Y; Ueda T; Mori A; Shimizu H; Haga Y; Yozu R
    J Vasc Surg; 2005 Oct; 42(4):765-71. PubMed ID: 16242566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuroprotective effects of N-methyl-D-aspartate receptor antagonist on aspartate induced neurotoxicity in the spinal cord in vivo.
    Cho Y; Ueda T; Mori A; Shimizu H; Yozu R
    Jpn J Thorac Cardiovasc Surg; 2003 Oct; 51(10):500-5. PubMed ID: 14621010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist.
    Schoepp DD; Smith CL; Lodge D; Millar JD; Leander JD; Sacaan AI; Lunn WH
    Eur J Pharmacol; 1991 Oct; 203(2):237-43. PubMed ID: 1686860
    [TBL] [Abstract][Full Text] [Related]  

  • 13. (3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist.
    Ornstein PL; Arnold MB; Allen NK; Leander JD; Tizzano JP; Lodge D; Schoepp DD
    J Med Chem; 1995 Dec; 38(25):4885-90. PubMed ID: 8523401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists.
    Hao JX; Xu XJ
    Pain; 1996 Aug; 66(2-3):279-85. PubMed ID: 8880851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.
    Hu LY; Guo J; Magar SS; Fischer JB; Burke-Howie KJ; Durant GJ
    J Med Chem; 1997 Dec; 40(26):4281-9. PubMed ID: 9435897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Competitive NMDA receptor antagonists and spinal-cord ischemia.
    Follis F; Blisard K; Varvitsiotis PS; Pett SB; Temes T; Wernly JA
    J Invest Surg; 2000; 13(2):117-21; discussion 123-4. PubMed ID: 10801049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syntheses, activity and modeling studies of 3- and 4-(sulfo- and sulfonamidoalkyl)pyridine and piperidine-2-carboxylic acid derivatives as analogs of NMDA receptor antagonists.
    el Hadri A; Maldivi P; Leclerc G; Rocher JP
    Bioorg Med Chem; 1995 Sep; 3(9):1183-201. PubMed ID: 8564410
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Systemic or intracerebroventricular injection of NMDA receptor antagonists attenuates the antinociceptive activity of intrathecally administered NMDA receptor antagonists.
    Näsström J; Karlsson U; Berge OG
    Brain Res; 1993 Sep; 623(1):47-55. PubMed ID: 8221092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury.
    Leem JW; Choi EJ; Park ES; Paik KS
    Neurosci Lett; 1996 Jun; 211(1):37-40. PubMed ID: 8809842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
    Cai SX; Kher SM; Zhou ZL; Ilyin V; Espitia SA; Tran M; Hawkinson JE; Woodward RM; Weber E; Keana JF
    J Med Chem; 1997 Feb; 40(5):730-8. PubMed ID: 9057859
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.