177 related articles for article (PubMed ID: 9871728)
1. The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases.
Levin JI; DiJoseph JF; Killar LM; Sharr MA; Skotnicki JS; Patel DV; Xiao XY; Shi L; Navre M; Campbell DA
Bioorg Med Chem Lett; 1998 May; 8(10):1163-8. PubMed ID: 9871728
[TBL] [Abstract][Full Text] [Related]
2. Malonyl alpha-mercaptoketones and alpha-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors.
Campbell DA; Xiao XY; Harris D; Ida S; Mortezaei R; Ngu K; Shi L; Tien D; Wang Y; Navre M; Patel DV; Sharr MA; DiJoseph JF; Killar LM; Leone CL; Levin JI; Skotnicki JS
Bioorg Med Chem Lett; 1998 May; 8(10):1157-62. PubMed ID: 9871727
[TBL] [Abstract][Full Text] [Related]
3. Design and synthesis of conformationally-constrained MMP inhibitors.
Natchus MG; Cheng M; Wahl CT; Pikul S; Almstead NG; Bradley RS; Taiwo YO; Mieling GE; Dunaway CM; Snider CE; McIver JM; Barnett BL; McPhail SJ; Anastasio MB; De B
Bioorg Med Chem Lett; 1998 Aug; 8(16):2077-80. PubMed ID: 9873489
[TBL] [Abstract][Full Text] [Related]
4. The design, synthesis, and structure-activity relationships of a series of macrocyclic MMP inhibitors.
Steinman DH; Curtin ML; Garland RB; Davidsen SK; Heyman HR; Holms JH; Albert DH; Magoc TJ; Nagy IB; Marcotte PA; Li J; Morgan DW; Hutchins C; Summers JB
Bioorg Med Chem Lett; 1998 Aug; 8(16):2087-92. PubMed ID: 9873491
[TBL] [Abstract][Full Text] [Related]
5. Difluoroketones as inhibitors of matrix metalloprotease-13.
Reiter LA; Martinelli GJ; Reeves LA; Mitchell PG
Bioorg Med Chem Lett; 2000 Jul; 10(14):1581-4. PubMed ID: 10915056
[TBL] [Abstract][Full Text] [Related]
6. Structure-based design and synthesis of a series of hydroxamic acids with a quaternary-hydroxy group in P1 as inhibitors of matrix metalloproteinases.
Jacobson IC; Reddy PG; Wasserman ZR; Hardman KD; Covington MB; Arner EC; Copeland RA; Decicco CP; Magolda RL
Bioorg Med Chem Lett; 1998 Apr; 8(7):837-42. PubMed ID: 9871551
[TBL] [Abstract][Full Text] [Related]
7. Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors.
Sheppard GS; Florjancic AS; Giesler JR; Xu L; Guo Y; Davidsen SK; Marcotte PA; Elmore I; Albert DH; Magoc TJ; Bouska JJ; Goodfellow CL; Morgan DW; Summers JB
Bioorg Med Chem Lett; 1998 Nov; 8(22):3251-6. PubMed ID: 9873712
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases.
Pikul S; McDow Dunham KL; Almstead NG; De B; Natchus MG; Anastasio MV; McPhail SJ; Snider CE; Taiwo YO; Chen L; Dunaway CM; Gu F; Mieling GE
J Med Chem; 1999 Jan; 42(1):87-94. PubMed ID: 9888835
[TBL] [Abstract][Full Text] [Related]
9. Discovery of a novel series of selective MMP inhibitors: identification of the gamma-sulfone-thiols.
Freskos JN; Mischke BV; DeCrescenzo GA; Heintz R; Getman DP; Howard SC; Kishore NN; McDonald JJ; Munie GE; Rangwala S; Swearingen CA; Voliva C; Welsch DJ
Bioorg Med Chem Lett; 1999 Apr; 9(7):943-8. PubMed ID: 10230616
[TBL] [Abstract][Full Text] [Related]
10. Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones.
Bandarage UK; Wang T; Come JH; Perola E; Wei Y; Rao BG
Bioorg Med Chem Lett; 2008 Jan; 18(1):44-8. PubMed ID: 18054488
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and evaluation of novel azasugar-based MMP/ADAM inhibitors.
Moriyama H; Tsukida T; Inoue Y; Kondo H; Yoshino K; Nishimura S
Bioorg Med Chem Lett; 2003 Aug; 13(16):2741-4. PubMed ID: 12873505
[TBL] [Abstract][Full Text] [Related]
12. Structure--activity relationships of azasugar-based MMP/ADAM inhibitors.
Moriyama H; Tsukida T; Inoue Y; Kondo H; Yoshino K; Nishimura S
Bioorg Med Chem Lett; 2003 Aug; 13(16):2737-40. PubMed ID: 12873504
[TBL] [Abstract][Full Text] [Related]
13. Selective, orally active MMP inhibitors with an aryl backbone.
Barta TE; Becker DP; Bedell LJ; De Crescenzo GA; McDonald JJ; Mehta P; Munie GE; Villamil CI
Bioorg Med Chem Lett; 2001 Sep; 11(18):2481-3. PubMed ID: 11549451
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S(1) pocket using conformationally constrained inhibitors.
Hanessian S; MacKay DB; Moitessier N
J Med Chem; 2001 Sep; 44(19):3074-82. PubMed ID: 11543676
[TBL] [Abstract][Full Text] [Related]
15. Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines.
Natchus MG; Bookland RG; Laufersweiler MJ; Pikul S; Almstead NG; De B; Janusz MJ; Hsieh LC; Gu F; Pokross ME; Patel VS; Garver SM; Peng SX; Branch TM; King SL; Baker TR; Foltz DJ; Mieling GE
J Med Chem; 2001 Mar; 44(7):1060-71. PubMed ID: 11297453
[TBL] [Abstract][Full Text] [Related]
16. N-Aryl sulfonyl homocysteine hydroxamate inhibitors of matrix metalloproteinases: further probing of the S(1), S(1)', and S(2)' pockets.
Hanessian S; Moitessier N; Gauchet C; Viau M
J Med Chem; 2001 Sep; 44(19):3066-73. PubMed ID: 11543675
[TBL] [Abstract][Full Text] [Related]
17. Matrix metalloproteinase inhibitors: a structure-activity study.
Levy DE; Lapierre F; Liang W; Ye W; Lange CW; Li X; Grobelny D; Casabonne M; Tyrrell D; Holme K; Nadzan A; Galardy RE
J Med Chem; 1998 Jan; 41(2):199-223. PubMed ID: 9457244
[TBL] [Abstract][Full Text] [Related]
18. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives.
Tamura Y; Watanabe F; Nakatani T; Yasui K; Fuji M; Komurasaki T; Tsuzuki H; Maekawa R; Yoshioka T; Kawada K; Sugita K; Ohtani M
J Med Chem; 1998 Feb; 41(4):640-9. PubMed ID: 9484512
[TBL] [Abstract][Full Text] [Related]
19. New type of metalloproteinase inhibitor: design and synthesis of new phosphonamide-based hydroxamic acids.
Sawa M; Kiyoi T; Kurokawa K; Kumihara H; Yamamoto M; Miyasaka T; Ito Y; Hirayama R; Inoue T; Kirii Y; Nishiwaki E; Ohmoto H; Maeda Y; Ishibushi E; Inoue Y; Yoshino K; Kondo H
J Med Chem; 2002 Feb; 45(4):919-29. PubMed ID: 11831904
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.
Fink CA; Moskal M; Firooznia F; Hoyer D; Symonsbergen D; Wei D; Qiao Y; Savage P; Beil ME; Trapani AJ; Jeng AY
Bioorg Med Chem Lett; 2000 Sep; 10(17):2037-9. PubMed ID: 10987444
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]