191 related articles for article (PubMed ID: 9872327)
1. A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.
Shen SX; Weaver Z; Xu X; Li C; Weinstein M; Chen L; Guan XY; Ried T; Deng CX
Oncogene; 1998 Dec; 17(24):3115-24. PubMed ID: 9872327
[TBL] [Abstract][Full Text] [Related]
2. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer.
Weaver Z; Montagna C; Xu X; Howard T; Gadina M; Brodie SG; Deng CX; Ried T
Oncogene; 2002 Aug; 21(33):5097-107. PubMed ID: 12140760
[TBL] [Abstract][Full Text] [Related]
3. Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice.
Brodie SG; Xu X; Qiao W; Li WM; Cao L; Deng CX
Oncogene; 2001 Nov; 20(51):7514-23. PubMed ID: 11709723
[TBL] [Abstract][Full Text] [Related]
4. Mammary tumor formation in p53- and BRCA1-deficient mice.
Cressman VL; Backlund DC; Hicks EM; Gowen LC; Godfrey V; Koller BH
Cell Growth Differ; 1999 Jan; 10(1):1-10. PubMed ID: 9950212
[TBL] [Abstract][Full Text] [Related]
5. The p53 mutational spectrum associated with BRCA1 mutant ovarian cancer.
Buller RE; Lallas TA; Shahin MS; Sood AK; Hatterman-Zogg M; Anderson B; Sorosky JI; Kirby PA
Clin Cancer Res; 2001 Apr; 7(4):831-8. PubMed ID: 11309330
[TBL] [Abstract][Full Text] [Related]
6. Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.
Deng CX; Scott F
Oncogene; 2000 Feb; 19(8):1059-64. PubMed ID: 10713690
[TBL] [Abstract][Full Text] [Related]
7. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
Xu X; Qiao W; Linke SP; Cao L; Li WM; Furth PA; Harris CC; Deng CX
Nat Genet; 2001 Jul; 28(3):266-71. PubMed ID: 11431698
[TBL] [Abstract][Full Text] [Related]
8. Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation.
Jeng YM; Cai-Ng S; Li A; Furuta S; Chew H; Chen PL; Lee EY; Lee WH
Oncogene; 2007 Sep; 26(42):6160-6. PubMed ID: 17420720
[TBL] [Abstract][Full Text] [Related]
9. The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells.
Fedier A; Steiner RA; Schwarz VA; Lenherr L; Haller U; Fink D
Int J Oncol; 2003 May; 22(5):1169-73. PubMed ID: 12684687
[TBL] [Abstract][Full Text] [Related]
10. Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice.
Deng CX
Mutat Res; 2001 Jun; 477(1-2):183-9. PubMed ID: 11376699
[TBL] [Abstract][Full Text] [Related]
11. Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation.
DelloRusso C; Welcsh PL; Wang W; Garcia RL; King MC; Swisher EM
Mol Cancer Res; 2007 Jan; 5(1):35-45. PubMed ID: 17259345
[TBL] [Abstract][Full Text] [Related]
12. Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.
Clark-Knowles KV; Garson K; Jonkers J; Vanderhyden BC
Exp Cell Res; 2007 Jan; 313(1):133-45. PubMed ID: 17070800
[TBL] [Abstract][Full Text] [Related]
13. Lessons learned from BRCA1 and BRCA2.
Zheng L; Li S; Boyer TG; Lee WH
Oncogene; 2000 Dec; 19(53):6159-75. PubMed ID: 11156530
[TBL] [Abstract][Full Text] [Related]
14. High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.
Holstege H; Joosse SA; van Oostrom CT; Nederlof PM; de Vries A; Jonkers J
Cancer Res; 2009 Apr; 69(8):3625-33. PubMed ID: 19336573
[TBL] [Abstract][Full Text] [Related]
15. Antisense inhibition of BRCA1 expression and molecular analysis of hereditary tumors indicate that functional inactivation of the p53 DNA damage response pathway is required for BRCA-associated tumorigenesis.
Reedy MB; Hang T; Gallion H; Arnold S; Smith SA
Gynecol Oncol; 2001 Jun; 81(3):441-6. PubMed ID: 11371136
[TBL] [Abstract][Full Text] [Related]
16. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Xu X; Wagner KU; Larson D; Weaver Z; Li C; Ried T; Hennighausen L; Wynshaw-Boris A; Deng CX
Nat Genet; 1999 May; 22(1):37-43. PubMed ID: 10319859
[TBL] [Abstract][Full Text] [Related]
17. Collaboration of Brca1 and Chk2 in tumorigenesis.
McPherson JP; Lemmers B; Hirao A; Hakem A; Abraham J; Migon E; Matysiak-Zablocki E; Tamblyn L; Sanchez-Sweatman O; Khokha R; Squire J; Hande MP; Mak TW; Hakem R
Genes Dev; 2004 May; 18(10):1144-53. PubMed ID: 15131084
[TBL] [Abstract][Full Text] [Related]
18. The Brca1 and Brca2 proteins and tumor pathogenesis.
Ingvarsson S
Anticancer Res; 1999; 19(4B):2853-61. PubMed ID: 10652564
[TBL] [Abstract][Full Text] [Related]
19. A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint.
Wang RH; Yu H; Deng CX
Proc Natl Acad Sci U S A; 2004 Dec; 101(49):17108-13. PubMed ID: 15563594
[TBL] [Abstract][Full Text] [Related]
20. Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice.
Bachelier R; Xu X; Wang X; Li W; Naramura M; Gu H; Deng CX
Oncogene; 2003 Jan; 22(4):528-37. PubMed ID: 12555066
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]