BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 9873035)

  • 1. Interleukin-1-induced nuclear factor-kappaB-IkappaBalpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulation of ikappabalpha resynthesis.
    Han Y; Meng T; Murray NR; Fields AP; Brasier AR
    J Biol Chem; 1999 Jan; 274(2):939-47. PubMed ID: 9873035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.
    Vertegaal AC; Kuiperij HB; Yamaoka S; Courtois G; van der Eb AJ; Zantema A
    Cell Signal; 2000 Dec; 12(11-12):759-68. PubMed ID: 11152962
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential IkappaB kinase activation and IkappaBalpha degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kappaB-dependent transcription.
    Nasuhara Y; Adcock IM; Catley M; Barnes PJ; Newton R
    J Biol Chem; 1999 Jul; 274(28):19965-72. PubMed ID: 10391945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation.
    Roussel RR; Barchowsky A
    Arch Biochem Biophys; 2000 May; 377(1):204-12. PubMed ID: 10775461
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism for biphasic rel A. NF-kappaB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes.
    Han Y; Brasier AR
    J Biol Chem; 1997 Apr; 272(15):9825-32. PubMed ID: 9092517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nuclear retention of IkappaBalpha protects it from signal-induced degradation and inhibits nuclear factor kappaB transcriptional activation.
    Rodriguez MS; Thompson J; Hay RT; Dargemont C
    J Biol Chem; 1999 Mar; 274(13):9108-15. PubMed ID: 10085161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor necrosis factor-alpha-induced apoptosis in prostate cancer cells through inhibition of nuclear factor-kappaB by an IkappaBalpha "super-repressor".
    Muenchen HJ; Lin DL; Walsh MA; Keller ET; Pienta KJ
    Clin Cancer Res; 2000 May; 6(5):1969-77. PubMed ID: 10815922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression.
    Natarajan K; Manna SK; Chaturvedi MM; Aggarwal BB
    Arch Biochem Biophys; 1998 Apr; 352(1):59-70. PubMed ID: 9521814
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y; Singh S; Aggarwal BB
    J Biol Chem; 2004 Apr; 279(15):15096-104. PubMed ID: 14711835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NF-kappa B activation in tumor necrosis factor alpha-stimulated neutrophils is mediated by protein kinase Cdelta. Correlation to nuclear Ikappa Balpha.
    Vancurova I; Miskolci V; Davidson D
    J Biol Chem; 2001 Jun; 276(23):19746-52. PubMed ID: 11274209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway.
    Bergmann M; Hart L; Lindsay M; Barnes PJ; Newton R
    J Biol Chem; 1998 Mar; 273(12):6607-10. PubMed ID: 9506955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell stress and MKK6b-mediated p38 MAP kinase activation inhibit tumor necrosis factor-induced IkappaB phosphorylation and NF-kappaB activation.
    Alpert D; Schwenger P; Han J; Vilcek J
    J Biol Chem; 1999 Aug; 274(32):22176-83. PubMed ID: 10428782
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells.
    Rahman A; Anwar KN; Malik AB
    Am J Physiol Cell Physiol; 2000 Oct; 279(4):C906-14. PubMed ID: 11003570
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IkappaBalpha (inhibitory kappaBalpha) identified as labile repressor of MnSOD (manganese superoxide dismutase) expression.
    Kiningham KK; Daosukho C; St Clair DK
    Biochem J; 2004 Dec; 384(Pt 3):543-9. PubMed ID: 15330761
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation.
    Han Y; Weinman S; Boldogh I; Walker RK; Brasier AR
    J Biol Chem; 1999 Jan; 274(2):787-94. PubMed ID: 9873017
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation.
    Wilson L; Szabó C; Salzman AL
    Gastroenterology; 1999 Jul; 117(1):106-14. PubMed ID: 10381916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.
    Kim S; Domon-Dell C; Kang J; Chung DH; Freund JN; Evers BM
    J Biol Chem; 2004 Feb; 279(6):4285-91. PubMed ID: 14623898
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transient nuclear factor kappaB (NF-kappaB) activation stimulated by interleukin-1beta may be partly dependent on proteasome activity, but not phosphorylation and ubiquitination of the IkappaBalpha molecule, in C6 glioma cells. Regulation of NF-kappaB linked to chemokine production.
    Uehara T; Matsuno J; Kaneko M; Nishiya T; Fujimuro M; Yokosawa H; Nomura Y
    J Biol Chem; 1999 May; 274(22):15875-82. PubMed ID: 10336492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ceramide inhibits IL-2 production by preventing protein kinase C-dependent NF-kappaB activation: possible role in protein kinase Ctheta regulation.
    Abboushi N; El-Hed A; El-Assaad W; Kozhaya L; El-Sabban ME; Bazarbachi A; Badreddine R; Bielawska A; Usta J; Dbaibo GS
    J Immunol; 2004 Sep; 173(5):3193-200. PubMed ID: 15322180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway.
    Chen CC; Sun YT; Chen JJ; Chiu KT
    J Immunol; 2000 Sep; 165(5):2719-28. PubMed ID: 10946303
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.