These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 9873507)

  • 21. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.
    Freeman GA; Andrews Iii CW; Hopkins AL; Lowell GS; Schaller LT; Cowan JR; Gonzales SS; Koszalka GW; Hazen RJ; Boone LR; Ferris RG; Creech KL; Roberts GB; Short SA; Weaver K; Reynolds DJ; Milton J; Ren J; Stuart DI; Stammers DK; Chan JH
    J Med Chem; 2004 Nov; 47(24):5923-36. PubMed ID: 15537347
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pyrazole NNRTIs 1: design and initial optimisation of a novel template.
    Mowbray CE; Burt C; Corbau R; Perros M; Tran I; Stupple PA; Webster R; Wood A
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5599-602. PubMed ID: 19709880
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis, and anti-HIV-1 activity of 1-aromatic methyl-substituted 3-(3,5-dimethylbenzyl)uracil and N-3,5-dimethylbenzyl-substituted urea derivatives.
    Sakakibara N; Baba M; Okamoto M; Toyama M; Demizu Y; Misawa T; Kurihara M; Irie K; Kato Y; Maruyama T
    Antivir Chem Chemother; 2015 Feb; 24(1):3-18. PubMed ID: 26149262
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
    Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutational analysis of trp-229 of human immunodeficiency virus type 1 reverse transcriptase (RT) identifies this amino acid residue as a prime target for the rational design of new non-nucleoside RT inhibitors.
    Pelemans H; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2000 May; 57(5):954-60. PubMed ID: 10779379
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
    Heeres J; de Jonge MR; Koymans LM; Daeyaert FF; Vinkers M; Van Aken KJ; Arnold E; Das K; Kilonda A; Hoornaert GJ; Compernolle F; Cegla M; Azzam RA; Andries K; de Béthune MP; Azijn H; Pauwels R; Lewi PJ; Janssen PA
    J Med Chem; 2005 Mar; 48(6):1910-8. PubMed ID: 15771435
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility.
    Frączek T; Kamiński R; Krakowiak A; Naessens E; Verhasselt B; Paneth P
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):9-16. PubMed ID: 29098886
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones.
    Kelly TA; McNeil DW; Rose JM; David E; Shih CK; Grob PM
    J Med Chem; 1997 Jul; 40(15):2430-3. PubMed ID: 9240358
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
    Hopkins AL; Ren J; Milton J; Hazen RJ; Chan JH; Stuart DI; Stammers DK
    J Med Chem; 2004 Nov; 47(24):5912-22. PubMed ID: 15537346
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants.
    Samuele A; Facchini M; Rotili D; Mai A; Artico M; Armand-Ugón M; Esté JA; Maga G
    ChemMedChem; 2008 Sep; 3(9):1412-8. PubMed ID: 18465760
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)].
    Zhou T; Xie L
    Yao Xue Xue Bao; 2004 Aug; 39(8):666-72. PubMed ID: 15563074
    [No Abstract]   [Full Text] [Related]  

  • 32. Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
    Campiani G; Aiello F; Fabbrini M; Morelli E; Ramunno A; Armaroli S; Nacci V; Garofalo A; Greco G; Novellino E; Maga G; Spadari S; Bergamini A; Ventura L; Bongiovanni B; Capozzi M; Bolacchi F; Marini S; Coletta M; Guiso G; Caccia S
    J Med Chem; 2001 Feb; 44(3):305-15. PubMed ID: 11462972
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design of nevirapine derivatives insensitive to the K103N and Y181C HIV-1 reverse transcriptase mutants.
    Saparpakorn P; Hannongbua S; Rognan D
    SAR QSAR Environ Res; 2006 Apr; 17(2):183-94. PubMed ID: 16644557
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.
    Mugnaini C; Alongi M; Togninelli A; Gevariya H; Brizzi A; Manetti F; Bernardini C; Angeli L; Tafi A; Bellucci L; Corelli F; Massa S; Maga G; Samuele A; Facchini M; Clotet-Codina I; Armand-Ugón M; Esté JA; Botta M
    J Med Chem; 2007 Dec; 50(26):6580-95. PubMed ID: 18052319
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
    Chan AH; Lee WG; Spasov KA; Cisneros JA; Kudalkar SN; Petrova ZO; Buckingham AB; Anderson KS; Jorgensen WL
    Proc Natl Acad Sci U S A; 2017 Sep; 114(36):9725-9730. PubMed ID: 28827354
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Docking of non-nucleoside inhibitors: neotripterifordin and its derivatives to HIV-1 reverse transcriptase.
    Zhou Z; Madrid M; Madura JD
    Proteins; 2002 Dec; 49(4):529-42. PubMed ID: 12402361
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.
    Campiani G; Morelli E; Fabbrini M; Nacci V; Greco G; Novellino E; Ramunno A; Maga G; Spadari S; Caliendo G; Bergamini A; Faggioli E; Uccella I; Bolacchi F; Marini S; Coletta M; Nacca A; Caccia S
    J Med Chem; 1999 Oct; 42(21):4462-70. PubMed ID: 10543890
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.
    Gavriliu D; Fossey C; Ciurea A; Delbederi Z; Sugeac E; Ladurée D; Schmidt S; Laumond G; Aubertin AM
    Nucleosides Nucleotides Nucleic Acids; 2002; 21(8-9):505-33. PubMed ID: 12484448
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Rational approaches for the design of effective human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitors.
    Ribone SR; Quevedo MA; Madrid M; Briñón MC
    J Chem Inf Model; 2011 Jan; 51(1):130-8. PubMed ID: 21133347
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide.
    La Regina G; Coluccia A; Brancale A; Piscitelli F; Gatti V; Maga G; Samuele A; Pannecouque C; Schols D; Balzarini J; Novellino E; Silvestri R
    J Med Chem; 2011 Mar; 54(6):1587-98. PubMed ID: 21366296
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.