BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 9873603)

  • 1. Design of a high affinity peptidomimetic opioid agonist from peptide pharmacophore models.
    Wang C; McFadyen IJ; Traynor JR; Mosberg HI
    Bioorg Med Chem Lett; 1998 Oct; 8(19):2685-8. PubMed ID: 9873603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The impact of β-azido(or 1-piperidinyl)methylamino acids in position 2 or 3 on biological activity and conformation of dermorphin analogues.
    Maciejczyk M; Lasota A; Frączak O; Kosson P; Misicka A; Nowakowski M; Ejchart A; Olma A
    J Pept Sci; 2016 Aug; 22(8):545-51. PubMed ID: 27443980
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
    Yamamoto T; Nair P; Jacobsen NE; Davis P; Ma SW; Navratilova E; Moye S; Lai J; Yamamura HI; Vanderah TW; Porreca F; Hruby VJ
    J Med Chem; 2008 Oct; 51(20):6334-47. PubMed ID: 18821747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclic opioid peptide agonists and antagonists obtained via ring-closing metathesis.
    Berezowska I; Lemieux C; Chung NN; Wilkes BC; Schiller PW
    Chem Biol Drug Des; 2009 Oct; 74(4):329-34. PubMed ID: 19694755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, biological evaluation, and automated docking of constrained analogues of the opioid peptide H-Dmt-D-Ala-Phe-Gly-NH₂ using the 4- or 5-methyl substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one scaffold.
    De Wachter R; de Graaf C; Keresztes A; Vandormael B; Ballet S; Tóth G; Rognan D; Tourwé D
    J Med Chem; 2011 Oct; 54(19):6538-47. PubMed ID: 21870874
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists.
    Boyd RE; Carson JR; Codd EE; Gauthier AD; Neilson LA; Zhang SP
    Bioorg Med Chem Lett; 2000 May; 10(10):1109-11. PubMed ID: 10843229
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
    Bonner GG; Davis P; Stropova D; Edsall S; Yamamura HI; Porreca F; Hruby VJ
    J Med Chem; 2000 Feb; 43(4):569-80. PubMed ID: 10691683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct influence of C-terminally substituted amino acids in the Dmt-Tic pharmacophore on delta-opioid receptor selectivity and antagonism.
    Balboni G; Salvadori S; Guerrini R; Negri L; Giannini E; Bryant SD; Jinsmaa Y; Lazarus LH
    J Med Chem; 2004 Jul; 47(16):4066-71. PubMed ID: 15267245
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biological properties of Phe(o)-opioid peptide analogues.
    Lipkowski AW; Misicka A; Hosohata K; Davis P; Yamamura HI; Porreca F; Hruby VJ
    Life Sci; 2001 Jan; 68(8):969-72. PubMed ID: 11213367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Opioid ligands with mixed mu/delta opioid receptor interactions: an emerging approach to novel analgesics.
    Ananthan S
    AAPS J; 2006 Mar; 8(1):E118-25. PubMed ID: 16584118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
    Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
    J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
    Liao S; Alfaro-Lopez J; Shenderovich MD; Hosohata K; Lin J; Li X; Stropova D; Davis P; Jernigan KA; Porreca F; Yamamura HI; Hruby VJ
    J Med Chem; 1998 Nov; 41(24):4767-76. PubMed ID: 9822547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stereospecific synthesis of (2S)-2-methyl-3-(2',6'-dimethyl-4'-hydroxyphenyl)-propionic acid (Mdp) and its incorporation into an opioid peptide.
    Lu Y; Weltrowska G; Lemieux C; Chung NN; Schiller PW
    Bioorg Med Chem Lett; 2001 Feb; 11(3):323-5. PubMed ID: 11212101
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of opioid peptides for a potential delta-receptor affinity label function: comparison with the mu-specific Tyr-D-Ala-Gly-(Me)Phe-chloromethyl ketone.
    Rónai AZ; Hepp J; Magyar A; Borsodi A; Medzihradszky K
    Pharmacology; 1994 Aug; 49(2):121-31. PubMed ID: 7972321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 6-N,N-dimethylamino-2,3-naphthalimide: a new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides.
    Vázquez ME; Blanco JB; Salvadori S; Trapella C; Argazzi R; Bryant SD; Jinsmaa Y; Lazarus LH; Negri L; Giannini E; Lattanzi R; Colucci M; Balboni G
    J Med Chem; 2006 Jun; 49(12):3653-8. PubMed ID: 16759107
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conversion of delta-, kappa- and mu-receptor selective opioid peptide agonists into delta-, kappa- and mu-selective antagonists.
    Schiller PW; Weltrowska G; Nguyen TM; Lemieux C; Chung NN; Lu Y
    Life Sci; 2003 Jun; 73(6):691-8. PubMed ID: 12801590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of opioid receptor-binding affinity of elaeocarpenine and its analogs.
    Kurasaki H; Okamoto I; Morita N; Tamura O
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1601-3. PubMed ID: 20144865
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold.
    Adamska-Bartłomiejczyk A; De Marco R; Gentilucci L; Kluczyk A; Janecka A
    Bioorg Med Chem; 2017 Apr; 25(8):2399-2405. PubMed ID: 28318893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Placement of Hydroxy Moiety on Pendant of Peptidomimetic Scaffold Modulates Mu and Kappa Opioid Receptor Efficacy.
    Harland AA; Pogozheva ID; Griggs NW; Trask TJ; Traynor JR; Mosberg HI
    ACS Chem Neurosci; 2017 Nov; 8(11):2549-2557. PubMed ID: 28796483
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.
    Wei ZY; Brown W; Takasaki B; Plobeck N; Delorme D; Zhou F; Yang H; Jones P; Gawell L; Gagnon H; Schmidt R; Yue SY; Walpole C; Payza K; St-Onge S; Labarre M; Godbout C; Jakob A; Butterworth J; Kamassah A; Morin PE; Projean D; Ducharme J; Roberts E
    J Med Chem; 2000 Oct; 43(21):3895-905. PubMed ID: 11052794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.