120 related articles for article (PubMed ID: 9873688)
1. Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives.
Venkatachalam TK; Tai HL; Vig R; Chen CL; Jan ST; Uckun FM
Bioorg Med Chem Lett; 1998 Nov; 8(22):3121-6. PubMed ID: 9873688
[TBL] [Abstract][Full Text] [Related]
2. D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non-toxic anti-human immunodeficiency virus agent.
Vig R; Venkatachalam TK; Uckun FM
Antivir Chem Chemother; 1998 Sep; 9(5):445-8. PubMed ID: 9875398
[TBL] [Abstract][Full Text] [Related]
3. AZT-5'-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent.
Jan ST; Zhu Z; Tai HL; Shih MJ; Venkatachalam TK; Uckun FM
Antivir Chem Chemother; 1999 Jan; 10(1):47-52. PubMed ID: 10079879
[TBL] [Abstract][Full Text] [Related]
4. WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
D'Cruz OJ; Zhu Z; Yiv SH; Chen CL; Waurzyniak B; Uckun FM
Contraception; 1999 May; 59(5):319-31. PubMed ID: 10494486
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
D'Cruz OJ; Shih MJ; Yiv SH; Chen CL; Uckun FM
Mol Hum Reprod; 1999 May; 5(5):421-32. PubMed ID: 10338365
[TBL] [Abstract][Full Text] [Related]
6. Metabolism and activities of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine in herpesvirus thymidine kinase transduced T-lymphocytes.
Drake RR; McMasters R; Krisa S; Hume SD; Rechtin TM; Saylors RL; Chiang Y; Govindarajan R; Munshi NC
Antiviral Res; 1997 Aug; 35(3):177-85. PubMed ID: 9298757
[TBL] [Abstract][Full Text] [Related]
7. Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jan; 62(1):37-44. PubMed ID: 10611065
[TBL] [Abstract][Full Text] [Related]
8. Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
Saboulard D; Naesens L; Cahard D; Salgado A; Pathirana R; Velazquez S; McGuigan C; De Clercq E; Balzarini J
Mol Pharmacol; 1999 Oct; 56(4):693-704. PubMed ID: 10496951
[TBL] [Abstract][Full Text] [Related]
9. Effects of aryl substituents on the anti-HIV activity of the arylphosphoramidate derivatives of stavudine.
Uckun FM; Samuel P; Qazi S; Chen C; Pendergrass S; Venkatachalam TK
Antivir Chem Chemother; 2002 May; 13(3):197-203. PubMed ID: 12448692
[TBL] [Abstract][Full Text] [Related]
10. Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
Paintsil E; Dutschman GE; Hu R; Grill SP; Lam W; Baba M; Tanaka H; Cheng YC
Antimicrob Agents Chemother; 2007 Nov; 51(11):3870-9. PubMed ID: 17724147
[TBL] [Abstract][Full Text] [Related]
11. Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
Uckun FM; Pendergrass S; Qazi S; Samuel P; Venkatachalam TK
Eur J Med Chem; 2004 Mar; 39(3):225-34. PubMed ID: 15051170
[TBL] [Abstract][Full Text] [Related]
12. Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.
Dutschman GE; Grill SP; Gullen EA; Haraguchi K; Takeda S; Tanaka H; Baba M; Cheng YC
Antimicrob Agents Chemother; 2004 May; 48(5):1640-6. PubMed ID: 15105115
[TBL] [Abstract][Full Text] [Related]
13. Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.
McGuigan C; Cahard D; Sheeka HM; De Clercq E; Balzarini J
J Med Chem; 1996 Apr; 39(8):1748-53. PubMed ID: 8648614
[TBL] [Abstract][Full Text] [Related]
14. Metabolism and anti-HIV activity of phosphoramidate derivatives of D4T-MP with variations in the amino acid moiety.
Naesens L; Cahard D; Salgado A; Bidois L; De Clercq E; McGuigan C; Balzarini J
Adv Exp Med Biol; 1998; 431():753-7. PubMed ID: 9598164
[TBL] [Abstract][Full Text] [Related]
15. In vivo pharmacokinetics and metabolism of anti-human immunodeficiency virus agent D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] (SAMPIDINE) in mice.
Chen CL; Venkatachalam TK; Zhu ZH; Uckun FM
Drug Metab Dispos; 2001 Jul; 29(7):1035-41. PubMed ID: 11408371
[TBL] [Abstract][Full Text] [Related]
16. The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.
Siddiqui AQ; Ballatore C; McGuigan C; De Clercq E; Balzarini J
J Med Chem; 1999 Feb; 42(3):393-9. PubMed ID: 9986709
[TBL] [Abstract][Full Text] [Related]
17. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno CF; De Clercq E; Meier C
Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and anti-HIV activity of some novel arylphosphate and H-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine.
Cardona VM; Ayi AI; Aubertin AM; Guedj R
Antiviral Res; 1999 Jul; 42(3):189-96. PubMed ID: 10443531
[TBL] [Abstract][Full Text] [Related]
19. Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides.
Shirokova EA; Jasko MV; Khandazhinskaya AL; Ivanov AV; Yanvarev DV; Skoblov YS; Mitkevich VA; Bocharov EV; Pronyaeva TR; Fedyuk NV; Kukhanova MK; Pokrovsky AG
J Med Chem; 2004 Jul; 47(14):3606-14. PubMed ID: 15214788
[TBL] [Abstract][Full Text] [Related]
20. Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity.
Ducho C; Balzarini J; Naesens L; De Clercq E; Meier C
Antivir Chem Chemother; 2002 Mar; 13(2):129-41. PubMed ID: 12238530
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
