117 related articles for article (PubMed ID: 9873720)
1. Efficient construction of 6-azasteroids: dual inhibitors of steroidal 5 alpha-reductase.
Sharp MJ; Fang FG
Bioorg Med Chem Lett; 1998 Dec; 8(23):3291-4. PubMed ID: 9873720
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and in vitro activity of 17 beta-(N-alkyl/arylformamido)- and 17 beta-[(N-alkyl/aryl)alkyl/arylamido]-4-methyl-4-aza-3-oxo-5 alpha-androstan-3-ones as inhibitors of human 5 alpha-reductases and antagonists of the androgen receptor.
Li X; Singh SM; Labrie F
J Med Chem; 1995 Mar; 38(7):1158-73. PubMed ID: 7707319
[TBL] [Abstract][Full Text] [Related]
3. Discovery and development of GG745, a potent inhibitor of both isozymes of 5 alpha-reductase.
Frye SV; Bramson HN; Hermann DJ; Lee FW; Sinhababu AK; Tian G
Pharm Biotechnol; 1998; 11():393-422. PubMed ID: 9760689
[No Abstract] [Full Text] [Related]
4. Stable expression of the human 5alpha-reductase isoenzymes type I and type II in HEK293 cells to identify dual and selective inhibitors.
Reichert W; Hartmann RW; Jose J
J Enzyme Inhib; 2001 Jan; 16(1):47-53. PubMed ID: 11496834
[TBL] [Abstract][Full Text] [Related]
5. In vitro inhibitory effects of 16-methyl-substituted steroids on 5 alpha-reductase in rat and human prostates.
Faredin I; Tóth I; Wölfling J; Schneider G; Meskó E
Steroids; 1994 Oct; 59(10):568-71. PubMed ID: 7533339
[TBL] [Abstract][Full Text] [Related]
6. Recent advances in the chemistry and pharmacological activity of new steroidal antiandrogens and 5 alpha-reductase inhibitors.
Bratoeff E; Cabeza M; Ramirez E; Heuze Y; Flores E
Curr Med Chem; 2005; 12(8):927-43. PubMed ID: 15853706
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of benzanilide derivatives as dual acting agents with alpha 1-adrenoceptor antagonistic action and steroid 5-alpha reductase inhibitory activity.
Yoshida K; Horikoshi Y; Eta M; Chikazawa J; Ogishima M; Fukuda Y; Sato H
Bioorg Med Chem Lett; 1998 Nov; 8(21):2967-72. PubMed ID: 9873656
[TBL] [Abstract][Full Text] [Related]
8. A practical synthesis of 3-substituted delta 3,5(6)-steroids as new potential 5 alpha-reductase inhibitor.
Tian W; Zhu Z; Liao Q; Wu Y
Bioorg Med Chem Lett; 1998 Aug; 8(15):1949-52. PubMed ID: 9873464
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and 5 alpha-reductase inhibitory activity of 8-substituted benzo[f]quinolinones derived from palladium mediated coupling reactions.
Smith EC; McQuaid LA; Goode RL; McNulty AM; Neubauer BL; Rocco VP; Audia JE
Bioorg Med Chem Lett; 1998 Feb; 8(4):395-8. PubMed ID: 9871692
[TBL] [Abstract][Full Text] [Related]
10. Structure activity relationship study of known inhibitors of the enzyme 5 alpha-reductase (5AR).
Ahmed S; Denison S
Bioorg Med Chem Lett; 1998 Mar; 8(5):409-14. PubMed ID: 9871588
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and pharmacological evaluation of new steroidal 5 alpha-reductase inhibitors.
Bratoeff E; Cabeza M; Flores E; Ramirez E; Quiroz A; Heuze I
Proc West Pharmacol Soc; 2002; 45():187-90. PubMed ID: 12434577
[No Abstract] [Full Text] [Related]
12. 3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: a self organizing molecular field analysis approach.
Aggarwal S; Thareja S; Bhardwaj TR; Kumar M
Eur J Med Chem; 2010 Feb; 45(2):476-81. PubMed ID: 19906465
[TBL] [Abstract][Full Text] [Related]
13. Neighboring group participation. Part 15. Stereoselective synthesis of some steroidal tetrahydrooxazin-2-ones, as novel presumed inhibitors of human 5alpha-reductase.
Wölfling J; Hackler L; Mernyák E; Schneider G; Tóth I; Szécsi M; Julesz J; Sohár P; Csámpai A
Steroids; 2004 Jul; 69(7):451-60. PubMed ID: 15246775
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and testosterone 5 alpha-reductase-inhibitory activity of 4-aza-5 alpha-androstane-17-carboxamide compound with an aromatic moiety in the C-17 carbamoyl group.
Kurata H; Ishibashi K; Saito S; Hamada T; Horikoshi H; Furukawa Y; Kojima K
Chem Pharm Bull (Tokyo); 1996 Jan; 44(1):115-21. PubMed ID: 8582030
[TBL] [Abstract][Full Text] [Related]
15. Substrate interaction with 5alpha-reductase enzyme: influence of the 17beta-chain chirality in the mechanism of action of 4-azasteroid inhibitors.
Grisenti P; Magni A; Olgiati V; Manzocchi A; Ferraboschi P; Villani V; Pucciariello R; Celotti F
Steroids; 2001 Nov; 66(11):803-10. PubMed ID: 11576619
[TBL] [Abstract][Full Text] [Related]
16. Identification and selective inhibition of an isozyme of steroid 5 alpha-reductase in human scalp.
Harris G; Azzolina B; Baginsky W; Cimis G; Rasmusson GH; Tolman RL; Raetz CR; Ellsworth K
Proc Natl Acad Sci U S A; 1992 Nov; 89(22):10787-91. PubMed ID: 1438277
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of 17beta-N-substituted 19-Nor-10-azasteroids as inhibitors of human 5alpha-reductases I and II.
Scarpi D; Occhiato EG; Danza G; Serio M; Guarna A
Bioorg Med Chem; 2002 Nov; 10(11):3455-61. PubMed ID: 12213459
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of androgen synthesis in human testicular and prostatic microsomes and in male rats by novel steroidal compounds.
Nnane IP; Kato K; Liu Y; Long BJ; Lu Q; Wang X; Ling YZ; Brodie A
Endocrinology; 1999 Jun; 140(6):2891-7. PubMed ID: 10342882
[TBL] [Abstract][Full Text] [Related]
19. QSARs for 6-azasteroids as inhibitors of human type 1 5alpha-reductase: prediction of binding affinity and selectivity relative to 3-BHSD.
Bakken GA; Jurs PC
J Chem Inf Comput Sci; 2001; 41(5):1255-65. PubMed ID: 11604025
[TBL] [Abstract][Full Text] [Related]
20. A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity.
Lew W; Wu H; Mendel DB; Escarpe PA; Chen X; Laver WG; Graves BJ; Kim CU
Bioorg Med Chem Lett; 1998 Dec; 8(23):3321-4. PubMed ID: 9873727
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]