159 related articles for article (PubMed ID: 9874193)
1. The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis.
Kouchi Z; Kinouchi T; Sorimachi H; Ishiura S; Suzuki K
Eur J Biochem; 1998 Dec; 258(2):291-300. PubMed ID: 9874193
[TBL] [Abstract][Full Text] [Related]
2. Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Caporaso GL; Gandy SE; Buxbaum JD; Greengard P
Proc Natl Acad Sci U S A; 1992 Mar; 89(6):2252-6. PubMed ID: 1549591
[TBL] [Abstract][Full Text] [Related]
3. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
Shin RW; Saido TC; Maeda M; Kitamoto T
Neurosci Lett; 2005 Mar; 376(1):14-9. PubMed ID: 15694266
[TBL] [Abstract][Full Text] [Related]
4. Intracellular site of gamma-secretase cleavage for Abeta42 generation in neuro 2a cells harbouring a presenilin 1 mutation.
Sudoh S; Hua G; Kawamura Y; Maruyama K; Komano H; Yanagisawa K
Eur J Biochem; 2000 Apr; 267(7):2036-45. PubMed ID: 10727943
[TBL] [Abstract][Full Text] [Related]
5. Deletion of an endosomal/lysosomal targeting signal promotes the secretion of Alzheimer's disease amyloid precursor protein (APP).
Ono Y; Kinouchi T; Sorimachi H; Ishiura S; Suzuki K
J Biochem; 1997 Mar; 121(3):585-90. PubMed ID: 9133629
[TBL] [Abstract][Full Text] [Related]
6. Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion.
Peraus GC; Masters CL; Beyreuther K
J Neurosci; 1997 Oct; 17(20):7714-24. PubMed ID: 9315893
[TBL] [Abstract][Full Text] [Related]
7. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
[TBL] [Abstract][Full Text] [Related]
8. The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells.
Kuentzel SL; Ali SM; Altman RA; Greenberg BD; Raub TJ
Biochem J; 1993 Oct; 295 ( Pt 2)(Pt 2):367-78. PubMed ID: 8240235
[TBL] [Abstract][Full Text] [Related]
9. Effect of ionophores on the processing of the beta-amyloid precursor protein in different cell lines.
Lahiri DK
Cell Mol Neurobiol; 1994 Aug; 14(4):297-313. PubMed ID: 7788640
[TBL] [Abstract][Full Text] [Related]
10. Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
Haass C; Koo EH; Capell A; Teplow DB; Selkoe DJ
J Cell Biol; 1995 Feb; 128(4):537-47. PubMed ID: 7860629
[TBL] [Abstract][Full Text] [Related]
11. Generation of beta A4 from the amyloid protein precursor and fragments thereof.
Dyrks T; Dyrks E; Mönning U; Urmoneit B; Turner J; Beyreuther K
FEBS Lett; 1993 Nov; 335(1):89-93. PubMed ID: 8243673
[TBL] [Abstract][Full Text] [Related]
12. Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein.
Fuller SJ; Storey E; Li QX; Smith AI; Beyreuther K; Masters CL
Biochemistry; 1995 Jun; 34(25):8091-8. PubMed ID: 7794922
[TBL] [Abstract][Full Text] [Related]
13. The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.
Yang Y; Turner RS; Gaut JR
J Biol Chem; 1998 Oct; 273(40):25552-5. PubMed ID: 9748217
[TBL] [Abstract][Full Text] [Related]
14. Role of endoplasmic reticulum, endosomal-lysosomal compartments, and microtubules in amyloid precursor protein metabolism of human neurons.
LeBlanc AC; Goodyer CG
J Neurochem; 1999 May; 72(5):1832-42. PubMed ID: 10217259
[TBL] [Abstract][Full Text] [Related]
15. Pulse-chase experiments revealed beta-secretase cleavage from immature full-length amyloid precursor protein harboring the Swedish mutation. Implications for distinct pathways.
Urmoneit B; Turner J; Dyrks T
J Mol Neurosci; 1998 Oct; 11(2):141-50. PubMed ID: 10096041
[TBL] [Abstract][Full Text] [Related]
16. A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP.
Skovronsky DM; Pijak DS; Doms RW; Lee VM
Biochemistry; 2000 Feb; 39(4):810-7. PubMed ID: 10651647
[TBL] [Abstract][Full Text] [Related]
17. Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.
De Strooper B; Umans L; Van Leuven F; Van Den Berghe H
J Cell Biol; 1993 Apr; 121(2):295-304. PubMed ID: 8468348
[TBL] [Abstract][Full Text] [Related]
18. beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide.
Paganetti P; Calanca V; Galli C; Stefani M; Molinari M
J Cell Biol; 2005 Mar; 168(6):863-8. PubMed ID: 15767460
[TBL] [Abstract][Full Text] [Related]
19. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
[TBL] [Abstract][Full Text] [Related]
20. Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.
Zhang W; Espinoza D; Hines V; Innis M; Mehta P; Miller DL
Biochim Biophys Acta; 1997 Nov; 1359(2):110-22. PubMed ID: 9409808
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
