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4. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. Nishina H; Bachmann M; Oliveira-dos-Santos AJ; Kozieradzki I; Fischer KD; Odermatt B; Wakeham A; Shahinian A; Takimoto H; Bernstein A; Mak TW; Woodgett JR; Ohashi PS; Penninger JM J Exp Med; 1997 Sep; 186(6):941-53. PubMed ID: 9294148 [TBL] [Abstract][Full Text] [Related]
5. SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Swat W; Fujikawa K; Ganiatsas S; Yang D; Xavier RJ; Harris NL; Davidson L; Ferrini R; Davis RJ; Labow MA; Flavell RA; Zon LI; Alt FW Immunity; 1998 May; 8(5):625-34. PubMed ID: 9620683 [TBL] [Abstract][Full Text] [Related]
6. Impaired TCR-mediated apoptosis and Bcl-XL expression in T cells lacking the stress kinase activator SEK1/MKK4. Nishina H; Radvanyi L; Raju K; Sasaki T; Kozieradzki I; Penninger JM J Immunol; 1998 Oct; 161(7):3416-20. PubMed ID: 9759859 [TBL] [Abstract][Full Text] [Related]
7. SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis. Ganiatsas S; Kwee L; Fujiwara Y; Perkins A; Ikeda T; Labow MA; Zon LI Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6881-6. PubMed ID: 9618507 [TBL] [Abstract][Full Text] [Related]
8. Dynamic expression of SEK1 suggests multiple roles of the gene during embryogenesis and in adult brain of mice. Lee JK; Hwang WS; Lee YD; Han PL Brain Res Mol Brain Res; 1999 Mar; 66(1-2):133-40. PubMed ID: 10095085 [TBL] [Abstract][Full Text] [Related]
9. Induction of cyclooxygenase-2 by the activated MEKK1 --> SEK1/MKK4 --> p38 mitogen-activated protein kinase pathway. Guan Z; Buckman SY; Pentland AP; Templeton DJ; Morrison AR J Biol Chem; 1998 May; 273(21):12901-8. PubMed ID: 9582321 [TBL] [Abstract][Full Text] [Related]
10. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Sánchez I; Hughes RT; Mayer BJ; Yee K; Woodgett JR; Avruch J; Kyriakis JM; Zon LI Nature; 1994 Dec 22-29; 372(6508):794-8. PubMed ID: 7997269 [TBL] [Abstract][Full Text] [Related]
11. MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase. Hirai Si; Katoh M; Terada M; Kyriakis JM; Zon LI; Rana A; Avruch J; Ohno S J Biol Chem; 1997 Jun; 272(24):15167-73. PubMed ID: 9182538 [TBL] [Abstract][Full Text] [Related]
12. Stress pathway activation induces phosphorylation of retinoid X receptor. Lee HY; Suh YA; Robinson MJ; Clifford JL; Hong WK; Woodgett JR; Cobb MH; Mangelsdorf DJ; Kurie JM J Biol Chem; 2000 Oct; 275(41):32193-9. PubMed ID: 10938283 [TBL] [Abstract][Full Text] [Related]
13. Multiple signaling pathways for the activation of JNK in mast cells: involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7. Kawakami Y; Hartman SE; Holland PM; Cooper JA; Kawakami T J Immunol; 1998 Aug; 161(4):1795-802. PubMed ID: 9712046 [TBL] [Abstract][Full Text] [Related]
14. JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Ito M; Yoshioka K; Akechi M; Yamashita S; Takamatsu N; Sugiyama K; Hibi M; Nakabeppu Y; Shiba T; Yamamoto KI Mol Cell Biol; 1999 Nov; 19(11):7539-48. PubMed ID: 10523642 [TBL] [Abstract][Full Text] [Related]
15. Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17. Yoshida BA; Dubauskas Z; Chekmareva MA; Christiano TR; Stadler WM; Rinker-Schaeffer CW Cancer Res; 1999 Nov; 59(21):5483-7. PubMed ID: 10554023 [TBL] [Abstract][Full Text] [Related]
16. A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses. Moriguchi T; Toyoshima F; Masuyama N; Hanafusa H; Gotoh Y; Nishida E EMBO J; 1997 Dec; 16(23):7045-53. PubMed ID: 9384583 [TBL] [Abstract][Full Text] [Related]
17. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. Teng DH; Perry WL; Hogan JK; Baumgard M; Bell R; Berry S; Davis T; Frank D; Frye C; Hattier T; Hu R; Jammulapati S; Janecki T; Leavitt A; Mitchell JT; Pero R; Sexton D; Schroeder M; Su PH; Swedlund B; Kyriakis JM; Avruch J; Bartel P; Wong AK; Tavtigian SV Cancer Res; 1997 Oct; 57(19):4177-82. PubMed ID: 9331070 [TBL] [Abstract][Full Text] [Related]
18. Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation. Wada T; Nakagawa K; Watanabe T; Nishitai G; Seo J; Kishimoto H; Kitagawa D; Sasaki T; Penninger JM; Nishina H; Katada T J Biol Chem; 2001 Aug; 276(33):30892-7. PubMed ID: 11418587 [TBL] [Abstract][Full Text] [Related]
19. Activation of JNK signaling pathway by erythropoietin, thrombopoietin, and interleukin-3. Nagata Y; Nishida E; Todokoro K Blood; 1997 Apr; 89(8):2664-9. PubMed ID: 9108383 [TBL] [Abstract][Full Text] [Related]
20. Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Yang D; Tournier C; Wysk M; Lu HT; Xu J; Davis RJ; Flavell RA Proc Natl Acad Sci U S A; 1997 Apr; 94(7):3004-9. PubMed ID: 9096336 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]