BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 9878436)

  • 1. Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex.
    Dauter Z; Persson R; Rosengren AM; Nyman PO; Wilson KS; Cedergren-Zeppezauer ES
    J Mol Biol; 1999 Jan; 285(2):655-73. PubMed ID: 9878436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
    Harris JM; McIntosh EM; Muscat GE
    J Mol Biol; 1999 Apr; 288(2):275-87. PubMed ID: 10329142
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases.
    Moroz OV; Harkiolaki M; Galperin MY; Vagin AA; González-Pacanowska D; Wilson KS
    J Mol Biol; 2004 Oct; 342(5):1583-97. PubMed ID: 15364583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site.
    Vertessy BG; Persson R; Rosengren AM; Zeppezauer M; Nyman PO
    Biochem Biophys Res Commun; 1996 Feb; 219(2):294-300. PubMed ID: 8604980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
    Kovári J; Barabás O; Varga B; Békési A; Tölgyesi F; Fidy J; Nagy J; Vértessy BG
    Proteins; 2008 Apr; 71(1):308-19. PubMed ID: 17932923
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of a dUTPase.
    Cedergren-Zeppezauer ES; Larsson G; Nyman PO; Dauter Z; Wilson KS
    Nature; 1992 Feb; 355(6362):740-3. PubMed ID: 1311056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
    Chan S; Segelke B; Lekin T; Krupka H; Cho US; Kim MY; So M; Kim CY; Naranjo CM; Rogers YC; Park MS; Waldo GS; Pashkov I; Cascio D; Perry JL; Sawaya MR
    J Mol Biol; 2004 Aug; 341(2):503-17. PubMed ID: 15276840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of equine infectious anemia virus proteinase complexed with an inhibitor.
    Gustchina A; Kervinen J; Powell DJ; Zdanov A; Kay J; Wlodawer A
    Protein Sci; 1996 Aug; 5(8):1453-65. PubMed ID: 8844837
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Incorporation of uracil into viral DNA correlates with reduced replication of EIAV in macrophages.
    Steagall WK; Robek MD; Perry ST; Fuller FJ; Payne SL
    Virology; 1995 Jul; 210(2):302-13. PubMed ID: 7542416
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis.
    Siggaard JH; Johansson E; Vognsen T; Helt SS; Harris P; Larsen S; Willemoës M
    Arch Biochem Biophys; 2009 Oct; 490(1):42-9. PubMed ID: 19683509
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structures of vaccinia virus dUTPase and its nucleotide complexes.
    Samal A; Schormann N; Cook WJ; DeLucas LJ; Chattopadhyay D
    Acta Crystallogr D Biol Crystallogr; 2007 May; 63(Pt 5):571-80. PubMed ID: 17452782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
    Tebbe J; Bzowska A; Wielgus-Kutrowska B; Schröder W; Kazimierczuk Z; Shugar D; Saenger W; Koellner G
    J Mol Biol; 1999 Dec; 294(5):1239-55. PubMed ID: 10600382
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes.
    Lokanath NK; Pampa KJ; Takio K; Kunishima N
    J Mol Biol; 2008 Jan; 375(4):1013-25. PubMed ID: 18062990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits.
    Mol CD; Harris JM; McIntosh EM; Tainer JA
    Structure; 1996 Sep; 4(9):1077-92. PubMed ID: 8805593
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of the genomic Bacillus subtilis dUTPase: novel features in the Phe-lid.
    García-Nafría J; Burchell L; Takezawa M; Rzechorzek NJ; Fogg MJ; Wilson KS
    Acta Crystallogr D Biol Crystallogr; 2010 Sep; 66(Pt 9):953-61. PubMed ID: 20823546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP).
    Larsson G; Svensson LA; Nyman PO
    Nat Struct Biol; 1996 Jun; 3(6):532-8. PubMed ID: 8646539
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
    Varga B; Barabás O; Kovári J; Tóth J; Hunyadi-Gulyás E; Klement E; Medzihradszky KF; Tölgyesi F; Fidy J; Vértessy BG
    FEBS Lett; 2007 Oct; 581(24):4783-8. PubMed ID: 17880943
    [TBL] [Abstract][Full Text] [Related]  

  • 18. dUTPase from the retrovirus equine infectious anemia virus: high-level expression in Escherichia coli and purification.
    Bergman AC; Björnberg O; Nord J; Rosengren AM; Nyman PO
    Protein Expr Purif; 1995 Jun; 6(3):379-87. PubMed ID: 7663176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
    Helt SS; Thymark M; Harris P; Aagaard C; Dietrich J; Larsen S; Willemoes M
    J Mol Biol; 2008 Feb; 376(2):554-69. PubMed ID: 18164314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The monomeric dUTPase from Epstein-Barr virus mimics trimeric dUTPases.
    Tarbouriech N; Buisson M; Seigneurin JM; Cusack S; Burmeister WP
    Structure; 2005 Sep; 13(9):1299-310. PubMed ID: 16154087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.