156 related articles for article (PubMed ID: 9882707)
1. A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel.
Li HL; Galue A; Meadows L; Ragsdale DS
Mol Pharmacol; 1999 Jan; 55(1):134-41. PubMed ID: 9882707
[TBL] [Abstract][Full Text] [Related]
2. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
Ragsdale DS; McPhee JC; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 1996 Aug; 93(17):9270-5. PubMed ID: 8799190
[TBL] [Abstract][Full Text] [Related]
3. Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel.
Qu Y; Rogers J; Tanada T; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 1995 Dec; 92(25):11839-43. PubMed ID: 8524860
[TBL] [Abstract][Full Text] [Related]
4. Molecular determinants of state-dependent block of Na+ channels by local anesthetics.
Ragsdale DS; McPhee JC; Scheuer T; Catterall WA
Science; 1994 Sep; 265(5179):1724-8. PubMed ID: 8085162
[TBL] [Abstract][Full Text] [Related]
5. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
Wright SN; Wang SY; Wang GK
Mol Pharmacol; 1998 Oct; 54(4):733-9. PubMed ID: 9765517
[TBL] [Abstract][Full Text] [Related]
6. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels.
Ahern CA; Eastwood AL; Dougherty DA; Horn R
Circ Res; 2008 Jan; 102(1):86-94. PubMed ID: 17967784
[TBL] [Abstract][Full Text] [Related]
7. Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.
Liu G; Yarov-Yarovoy V; Nobbs M; Clare JJ; Scheuer T; Catterall WA
Neuropharmacology; 2003 Mar; 44(3):413-22. PubMed ID: 12604088
[TBL] [Abstract][Full Text] [Related]
8. Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.
Weiser T; Qu Y; Catterall WA; Scheuer T
Mol Pharmacol; 1999 Dec; 56(6):1238-44. PubMed ID: 10570051
[TBL] [Abstract][Full Text] [Related]
9. Molecular properties of brain sodium channels: an important target for anticonvulsant drugs.
Catterall WA
Adv Neurol; 1999; 79():441-56. PubMed ID: 10514834
[TBL] [Abstract][Full Text] [Related]
10. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
Wang SY; Nau C; Wang GK
Biophys J; 2000 Sep; 79(3):1379-87. PubMed ID: 10969000
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of local anesthetic drug action on voltage-gated sodium channels.
Fozzard HA; Lee PJ; Lipkind GM
Curr Pharm Des; 2005; 11(21):2671-86. PubMed ID: 16101448
[TBL] [Abstract][Full Text] [Related]
12. Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.
Yarov-Yarovoy V; McPhee JC; Idsvoog D; Pate C; Scheuer T; Catterall WA
J Biol Chem; 2002 Sep; 277(38):35393-401. PubMed ID: 12130650
[TBL] [Abstract][Full Text] [Related]
13. New insights into the therapeutic inhibition of voltage-gated sodium channels.
Ahern CA; Eastwood AL; Dougherty DA; Horn R
Channels (Austin); 2008; 2(1):1-3. PubMed ID: 18690056
[TBL] [Abstract][Full Text] [Related]
14. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers.
Nau C; Wang SY; Strichartz GR; Wang GK
Mol Pharmacol; 1999 Aug; 56(2):404-13. PubMed ID: 10419561
[TBL] [Abstract][Full Text] [Related]
15. State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain.
Wang GK; Russell C; Wang SY
Pain; 2004 Jul; 110(1-2):166-74. PubMed ID: 15275764
[TBL] [Abstract][Full Text] [Related]
16. Molecular mechanisms of local anesthesia: a review.
Butterworth JF; Strichartz GR
Anesthesiology; 1990 Apr; 72(4):711-34. PubMed ID: 2157353
[TBL] [Abstract][Full Text] [Related]
17. Mechanism of tetracaine block of cyclic nucleotide-gated channels.
Fodor AA; Gordon SE; Zagotta WN
J Gen Physiol; 1997 Jan; 109(1):3-14. PubMed ID: 8997661
[TBL] [Abstract][Full Text] [Related]
18. Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers.
Nau C; Wang SY; Wang GK
Mol Pharmacol; 2003 Jun; 63(6):1398-406. PubMed ID: 12761351
[TBL] [Abstract][Full Text] [Related]
19. Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding.
Scheib H; McLay I; Guex N; Clare JJ; Blaney FE; Dale TJ; Tate SN; Robertson GM
J Mol Model; 2006 Sep; 12(6):813-22. PubMed ID: 16508760
[TBL] [Abstract][Full Text] [Related]
20. Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
Wang SY; Mitchell J; Moczydlowski E; Wang GK
J Gen Physiol; 2004 Dec; 124(6):691-701. PubMed ID: 15545401
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]