286 related articles for article (PubMed ID: 9887328)
21. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.
Clemens LE; Weber JJ; Wlodkowski TT; Yu-Taeger L; Michaud M; Calaminus C; Eckert SH; Gaca J; Weiss A; Magg JC; Jansson EK; Eckert GP; Pichler BJ; Bordet T; Pruss RM; Riess O; Nguyen HP
Brain; 2015 Dec; 138(Pt 12):3632-53. PubMed ID: 26490331
[TBL] [Abstract][Full Text] [Related]
22. Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease.
Petrasch-Parwez E; Nguyen HP; Löbbecke-Schumacher M; Habbes HW; Wieczorek S; Riess O; Andres KH; Dermietzel R; Von Hörsten S
J Comp Neurol; 2007 Apr; 501(5):716-30. PubMed ID: 17299753
[TBL] [Abstract][Full Text] [Related]
23. Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model.
Weiss KR; Kimura Y; Lee WC; Littleton JT
Genetics; 2012 Feb; 190(2):581-600. PubMed ID: 22095086
[TBL] [Abstract][Full Text] [Related]
24. Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease.
Weiss A; Klein C; Woodman B; Sathasivam K; Bibel M; Régulier E; Bates GP; Paganetti P
J Neurochem; 2008 Feb; 104(3):846-58. PubMed ID: 17986219
[TBL] [Abstract][Full Text] [Related]
25. 14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein.
Omi K; Hachiya NS; Tanaka M; Tokunaga K; Kaneko K
Neurosci Lett; 2008 Jan; 431(1):45-50. PubMed ID: 18078716
[TBL] [Abstract][Full Text] [Related]
26. Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease.
Trushina E; Heldebrant MP; Perez-Terzic CM; Bortolon R; Kovtun IV; Badger JD; Terzic A; Estévez A; Windebank AJ; Dyer RB; Yao J; McMurray CT
Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12171-6. PubMed ID: 14527999
[TBL] [Abstract][Full Text] [Related]
27. Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.
Sayer JA; Manczak M; Akileswaran L; Reddy PH; Coghlan VM
Neuromolecular Med; 2005; 7(4):297-310. PubMed ID: 16391387
[TBL] [Abstract][Full Text] [Related]
28. Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.
Tanaka K; Shouguchi-Miyata J; Miyamoto N; Ikeda JE
J Biol Chem; 2004 Feb; 279(8):7275-86. PubMed ID: 14625278
[TBL] [Abstract][Full Text] [Related]
29. Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation.
De Rooij KE; Dorsman JC; Smoor MA; Den Dunnen JT; Van Ommen GJ
Hum Mol Genet; 1996 Aug; 5(8):1093-9. PubMed ID: 8842726
[TBL] [Abstract][Full Text] [Related]
30. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Orr AL; Li S; Wang CE; Li H; Wang J; Rong J; Xu X; Mastroberardino PG; Greenamyre JT; Li XJ
J Neurosci; 2008 Mar; 28(11):2783-92. PubMed ID: 18337408
[TBL] [Abstract][Full Text] [Related]
31. The influence of huntingtin protein size on nuclear localization and cellular toxicity.
Hackam AS; Singaraja R; Wellington CL; Metzler M; McCutcheon K; Zhang T; Kalchman M; Hayden MR
J Cell Biol; 1998 Jun; 141(5):1097-105. PubMed ID: 9606203
[TBL] [Abstract][Full Text] [Related]
32. Mutant protein in Huntington disease is resistant to proteolysis in affected brain.
Dyer RB; McMurray CT
Nat Genet; 2001 Nov; 29(3):270-8. PubMed ID: 11600884
[TBL] [Abstract][Full Text] [Related]
33. Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Atwal RS; Xia J; Pinchev D; Taylor J; Epand RM; Truant R
Hum Mol Genet; 2007 Nov; 16(21):2600-15. PubMed ID: 17704510
[TBL] [Abstract][Full Text] [Related]
34. Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin.
Bao J; Sharp AH; Wagster MV; Becher M; Schilling G; Ross CA; Dawson VL; Dawson TM
Proc Natl Acad Sci U S A; 1996 May; 93(10):5037-42. PubMed ID: 8643525
[TBL] [Abstract][Full Text] [Related]
35. Mutant huntingtin forms in vivo complexes with distinct context-dependent conformations of the polyglutamine segment.
Persichetti F; Trettel F; Huang CC; Fraefel C; Timmers HT; Gusella JF; MacDonald ME
Neurobiol Dis; 1999 Oct; 6(5):364-75. PubMed ID: 10527804
[TBL] [Abstract][Full Text] [Related]
36. Ultrastructure of nuclear aggregates formed by expressing an expanded polyglutamine.
Hazeki N; Tsukamoto T; Yazawa I; Koyama M; Hattori S; Someki I; Iwatsubo T; Nakamura K; Goto J; Kanazawa I
Biochem Biophys Res Commun; 2002 Jun; 294(2):429-40. PubMed ID: 12051730
[TBL] [Abstract][Full Text] [Related]
37. Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates.
Yan Y; Peng D; Tian J; Chi J; Tan J; Yin X; Pu J; Xia K; Zhang B
Sci China Life Sci; 2011 Apr; 54(4):342-50. PubMed ID: 21509658
[TBL] [Abstract][Full Text] [Related]
38. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease.
Benn CL; Landles C; Li H; Strand AD; Woodman B; Sathasivam K; Li SH; Ghazi-Noori S; Hockly E; Faruque SM; Cha JH; Sharpe PT; Olson JM; Li XJ; Bates GP
Hum Mol Genet; 2005 Oct; 14(20):3065-78. PubMed ID: 16183657
[TBL] [Abstract][Full Text] [Related]
39. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
Ho LW; Brown R; Maxwell M; Wyttenbach A; Rubinsztein DC
J Med Genet; 2001 Jul; 38(7):450-2. PubMed ID: 11432963
[TBL] [Abstract][Full Text] [Related]
40. Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
Scherzinger E; Lurz R; Turmaine M; Mangiarini L; Hollenbach B; Hasenbank R; Bates GP; Davies SW; Lehrach H; Wanker EE
Cell; 1997 Aug; 90(3):549-58. PubMed ID: 9267034
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]