BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 9916803)

  • 1. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.
    Morales CP; Holt SE; Ouellette M; Kaur KJ; Yan Y; Wilson KS; White MA; Wright WE; Shay JW
    Nat Genet; 1999 Jan; 21(1):115-8. PubMed ID: 9916803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
    Wadhwa R; Takano S; Taira K; Kaul SC
    J Gene Med; 2004 Apr; 6(4):439-44. PubMed ID: 15079818
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.
    MacKenzie KL; Franco S; May C; Sadelain M; Moore MA
    Exp Cell Res; 2000 Sep; 259(2):336-50. PubMed ID: 10964501
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells.
    Zhuang ZH; Tsao SW; Deng W; Wang JD; Xia HH; He H; Feng HC; Wang LD; Gu Q; Lam SK; Lin MC; Kung HF; Wong BC
    J Gastroenterol Hepatol; 2008 Oct; 23(10):1613-20. PubMed ID: 18717758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
    Kiyono T; Foster SA; Koop JI; McDougall JK; Galloway DA; Klingelhutz AJ
    Nature; 1998 Nov; 396(6706):84-8. PubMed ID: 9817205
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
    Zhang H; Jin Y; Chen X; Jin C; Law S; Tsao SW; Kwong YL
    Cancer Lett; 2007 Jan; 245(1-2):184-94. PubMed ID: 16488074
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells.
    Jarrard DF; Sarkar S; Shi Y; Yeager TR; Magrane G; Kinoshita H; Nassif N; Meisner L; Newton MA; Waldman FM; Reznikoff CA
    Cancer Res; 1999 Jun; 59(12):2957-64. PubMed ID: 10383161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knockdown of p53 combined with expression of the catalytic subunit of telomerase is sufficient to immortalize primary human ovarian surface epithelial cells.
    Yang G; Rosen DG; Mercado-Uribe I; Colacino JA; Mills GB; Bast RC; Zhou C; Liu J
    Carcinogenesis; 2007 Jan; 28(1):174-82. PubMed ID: 16829690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.
    Milyavsky M; Shats I; Erez N; Tang X; Senderovich S; Meerson A; Tabach Y; Goldfinger N; Ginsberg D; Harris CC; Rotter V
    Cancer Res; 2003 Nov; 63(21):7147-57. PubMed ID: 14612508
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7.
    Sdek P; Zhang ZY; Cao J; Pan HY; Chen WT; Zheng JW
    Int J Oral Maxillofac Surg; 2006 Jul; 35(7):653-7. PubMed ID: 16513324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres.
    Goodwin EC; DiMaio D
    Cell Growth Differ; 2001 Nov; 12(11):525-34. PubMed ID: 11714633
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Replicative senescence of normal human oral keratinocytes is associated with the loss of telomerase activity without shortening of telomeres.
    Kang MK; Guo W; Park NH
    Cell Growth Differ; 1998 Jan; 9(1):85-95. PubMed ID: 9438392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genomic instability and telomerase activity in human bronchial epithelial cells during immortalization by human papillomavirus-16 E6 and E7 genes.
    Coursen JD; Bennett WP; Gollahon L; Shay JW; Harris CC
    Exp Cell Res; 1997 Aug; 235(1):245-53. PubMed ID: 9281374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53.
    Sima N; Wang W; Kong D; Deng D; Xu Q; Zhou J; Xu G; Meng L; Lu Y; Wang S; Ma D
    Apoptosis; 2008 Feb; 13(2):273-81. PubMed ID: 18060502
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of the HPV E7 oncoprotein mimics but does not evoke a p53-dependent cellular DNA damage response pathway.
    Jones DL; Thompson DA; Suh-Bürgmann E; Grace M; Münger K
    Virology; 1999 Jun; 258(2):406-14. PubMed ID: 10366578
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Keratinocyte growth conditions modulate telomerase expression, senescence, and immortalization by human papillomavirus type 16 E6 and E7 oncogenes.
    Fu B; Quintero J; Baker CC
    Cancer Res; 2003 Nov; 63(22):7815-24. PubMed ID: 14633708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.
    Harada H; Nakagawa H; Oyama K; Takaoka M; Andl CD; Jacobmeier B; von Werder A; Enders GH; Opitz OG; Rustgi AK
    Mol Cancer Res; 2003 Aug; 1(10):729-38. PubMed ID: 12939398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Replicative senescence in sheep fibroblasts is a p53 dependent process.
    Davis T; Skinner JW; Faragher RG; Jones CJ; Kipling D
    Exp Gerontol; 2005; 40(1-2):17-26. PubMed ID: 15664728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts.
    Wei S; Wei S; Sedivy JM
    Cancer Res; 1999 Apr; 59(7):1539-43. PubMed ID: 10197626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.
    Takaoka M; Harada H; Deramaudt TB; Oyama K; Andl CD; Johnstone CN; Rhoades B; Enders GH; Opitz OG; Nakagawa H
    Oncogene; 2004 Sep; 23(40):6760-8. PubMed ID: 15273725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.