125 related articles for article (PubMed ID: 9918136)
1. Determination of the enzymes responsible for activation of the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline in the human breast.
Williams JA; Stone EM; Millar BC; Gusterson BA; Grover PL; Phillips DH
Pharmacogenetics; 1998 Dec; 8(6):519-28. PubMed ID: 9918136
[TBL] [Abstract][Full Text] [Related]
2. Pathways of heterocyclic amine activation in the breast: DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) formed by peroxidases and in human mammary epithelial cells and fibroblasts.
Williams JA; Stone EM; Millar BC; Hewer A; Phillips DH
Mutagenesis; 2000 Mar; 15(2):149-54. PubMed ID: 10719041
[TBL] [Abstract][Full Text] [Related]
3. Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
Fan L; Schut HA; Snyderwine EG
Carcinogenesis; 1995 Apr; 16(4):775-9. PubMed ID: 7728954
[TBL] [Abstract][Full Text] [Related]
4. Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Stone EM; Williams JA; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1998 May; 19(5):873-9. PubMed ID: 9635877
[TBL] [Abstract][Full Text] [Related]
5. N-Acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast.
Williams JA; Stone EM; Fakis G; Johnson N; Cordell JA; Meinl W; Glatt H; Sim E; Phillips DH
Pharmacogenetics; 2001 Jul; 11(5):373-88. PubMed ID: 11470991
[TBL] [Abstract][Full Text] [Related]
6. Metabolic activation of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) to DNA binding species in human mammary epithelial cells.
Pfau W; O'Hare MJ; Grover PL; Phillips DH
Carcinogenesis; 1992 May; 13(5):907-9. PubMed ID: 1587008
[TBL] [Abstract][Full Text] [Related]
7. Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
Edwards RJ; Murray BP; Murray S; Schulz T; Neubert D; Gant TW; Thorgeirsson SS; Boobis AR; Davies DS
Carcinogenesis; 1994 May; 15(5):829-36. PubMed ID: 8200083
[TBL] [Abstract][Full Text] [Related]
8. Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4, 5-f]quinoline.
Agus C; Ilett KF; Kadlubar FF; Minchin RF
Carcinogenesis; 2000 Jun; 21(6):1213-9. PubMed ID: 10837012
[TBL] [Abstract][Full Text] [Related]
9. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Sadrieh N; Snyderwine EG
Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.
Williams JA; Martin FL; Muir GH; Hewer A; Grover PL; Phillips DH
Carcinogenesis; 2000 Sep; 21(9):1683-9. PubMed ID: 10964100
[TBL] [Abstract][Full Text] [Related]
11. Inhibitory effect of dietary 4-ipomeanol on DNA adduct formation by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in male CDF1 mice.
Cummings DA; Schut HA
Carcinogenesis; 1995 Oct; 16(10):2523-9. PubMed ID: 7586161
[TBL] [Abstract][Full Text] [Related]
12. Ahr locus phenotype in congenic mice influences hepatic and pulmonary DNA adduct levels of 2-amino-3-methylimidazo[4,5-f]quinoline in the absence of cytochrome P450 induction.
Nerurkar PV; Schut HA; Anderson LM; Riggs CW; Fornwald LW; Davis CD; Snyderwine EG; Thorgeirsson SS; Weber WW; Rice JM; Levy GN
Mol Pharmacol; 1996 May; 49(5):874-81. PubMed ID: 8622637
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adducts by indole-3-carbinol: dose-response studies in the rat colon.
Xu M; Schut HA; Bjeldanes LF; Williams DE; Bailey GS; Dashwood RH
Carcinogenesis; 1997 Nov; 18(11):2149-53. PubMed ID: 9395215
[TBL] [Abstract][Full Text] [Related]
14. Identification of new 2-amino-3-methylimidazo[4,5-f]quinoline urinary metabolites from beta-naphthoflavone-treated mice.
Lakshmi VM; Hsu FF; Zenser TV
Drug Metab Dispos; 2009 Aug; 37(8):1690-7. PubMed ID: 19451400
[TBL] [Abstract][Full Text] [Related]
15. Cytochrome P4501A2 constitutively expressed from transduced DNA mediates metabolic activation and DNA-adduct formation of aromatic amine carcinogens in NIH 3T3 cells.
Battula N; Schut HA; Thorgeirsson SS
Mol Carcinog; 1991; 4(5):407-14. PubMed ID: 1910484
[TBL] [Abstract][Full Text] [Related]
16. The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: a structure-activity relationship study.
Edenharder R; Rauscher R; Platt KL
Mutat Res; 1997 Sep; 379(1):21-32. PubMed ID: 9330619
[TBL] [Abstract][Full Text] [Related]
17. DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5- f]quinoline at the C-8 and N2 atoms of guanine.
Turesky RJ; Markovic J
Chem Res Toxicol; 1994; 7(6):752-61. PubMed ID: 7696529
[TBL] [Abstract][Full Text] [Related]
18. Metabolic activation and DNA binding of food mutagens and other environmental carcinogens in human mammary epithelial cells.
Carmichael PL; Stone EM; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1996 Aug; 17(8):1769-72. PubMed ID: 8761441
[TBL] [Abstract][Full Text] [Related]
19. Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4,5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase.
Anari MR; Josephy PD; Henry T; O'Brien PJ
Chem Res Toxicol; 1997 May; 10(5):582-8. PubMed ID: 9168257
[TBL] [Abstract][Full Text] [Related]
20. The role of the human acetylation polymorphism in the metabolic activation of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).
Probst MR; Blum M; Fasshauer I; D'Orazio D; Meyer UA; Wild D
Carcinogenesis; 1992 Oct; 13(10):1713-7. PubMed ID: 1423830
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
