222 related articles for article (PubMed ID: 9920857)
1. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Rots MG; Pieters R; Kaspers GJ; van Zantwijk CH; Noordhuis P; Mauritz R; Veerman AJ; Jansen G; Peters GJ
Blood; 1999 Feb; 93(3):1067-74. PubMed ID: 9920857
[TBL] [Abstract][Full Text] [Related]
2. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
Mauritz R; Bekkenk MW; Rots MG; Pieters R; Mini E; van Zantwijk CH; Veerman AJ; Peters GJ; Jansen G
Clin Cancer Res; 1998 Oct; 4(10):2399-410. PubMed ID: 9796971
[TBL] [Abstract][Full Text] [Related]
3. Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.
Rots MG; Pieters R; Peters GJ; van Zantwijk CH; Mauritz R; Noordhuis P; Willey JC; Hählen K; Creutzig U; Janka-Schaub G; Kaspers GJ; Veerman AJ; Jansen G
Blood; 1999 Nov; 94(9):3121-8. PubMed ID: 10556198
[TBL] [Abstract][Full Text] [Related]
4. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
Jaramillo AC; Cloos J; Lemos C; Stam RW; Kaspers GJL; Jansen G; Peters GJ
Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
[TBL] [Abstract][Full Text] [Related]
5. Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay.
Lingg RM; Hempel G; Rots MG; Van Zantwijk CH; Boos J; Kaspers GJ
Cancer Chemother Pharmacol; 2005 Sep; 56(3):322-7. PubMed ID: 15868145
[TBL] [Abstract][Full Text] [Related]
6. A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia.
Rots MG; Pieters R; Jansen G; Kaspers GJ; Van Zantwijk CH; Noordhuis P; Voorn DA; Van Wering ER; Creutzig U; Veerman AJ; Peters GJ
Eur J Cancer; 2001 Mar; 37(4):492-8. PubMed ID: 11267859
[TBL] [Abstract][Full Text] [Related]
7. Mechanisms of resistance to methotrexate in childhood acute lymphoblastic leukemia: circumvention of thymidylate synthase inhibition.
Weigand M; Frei E; Graf N; Buchholz B; Wolfrom C; Breuer A; Wiessler M
J Cancer Res Clin Oncol; 1999; 125(8-9):513-9. PubMed ID: 10480345
[TBL] [Abstract][Full Text] [Related]
8. Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells.
Longo GS; Gorlick R; Tong WP; Ercikan E; Bertino JR
Blood; 1997 Aug; 90(3):1241-5. PubMed ID: 9242558
[TBL] [Abstract][Full Text] [Related]
9. mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method.
Rots MG; Willey JC; Jansen G; Van Zantwijk CH; Noordhuis P; DeMuth JP; Kuiper E; Veerman AJ; Pieters R; Peters GJ
Leukemia; 2000 Dec; 14(12):2166-75. PubMed ID: 11187907
[TBL] [Abstract][Full Text] [Related]
10. Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.
Rots MG; Pieters R; Peters GJ; Noordhuis P; van Zantwijk CH; Kaspers GJ; Hählen K; Creutzig U; Veerman AJ; Jansen G
Blood; 1999 Mar; 93(5):1677-83. PubMed ID: 10029597
[TBL] [Abstract][Full Text] [Related]
11. Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells.
Barnes MJ; Taylor GA; Newell DR
Biochem Pharmacol; 2000 Feb; 59(4):321-8. PubMed ID: 10644039
[TBL] [Abstract][Full Text] [Related]
12. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
[TBL] [Abstract][Full Text] [Related]
13. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
[TBL] [Abstract][Full Text] [Related]
14. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
Hum MC; Smith AK; Lark RH; Winick NJ; Kamen BA
Pharmacotherapy; 1997; 17(6):1260-6. PubMed ID: 9399609
[TBL] [Abstract][Full Text] [Related]
15. Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia.
Rots MG; Pieters R; Peters GJ; Noordhuis P; Van Zantwijk CH; Henze G; Janka-Schaub GE; Veerman AJ; Jansen G
Br J Haematol; 2000 Jun; 109(3):629-34. PubMed ID: 10886214
[TBL] [Abstract][Full Text] [Related]
16. 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.
McGuire JJ; Haile WH; Yeh CC
Cancer Res; 2006 Apr; 66(7):3836-44. PubMed ID: 16585211
[TBL] [Abstract][Full Text] [Related]
17. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
McGuire JJ; Magee KJ; Russell CA; Canestrari JM
Oncol Res; 1997; 9(3):139-47. PubMed ID: 9220499
[TBL] [Abstract][Full Text] [Related]
18. Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia.
Trippett T; Schlemmer S; Elisseyeff Y; Goker E; Wachter M; Steinherz P; Tan C; Berman E; Wright JE; Rosowsky A
Blood; 1992 Sep; 80(5):1158-62. PubMed ID: 1381235
[TBL] [Abstract][Full Text] [Related]
19. Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.
Wojtuszkiewicz A; Peters GJ; van Woerden NL; Dubbelman B; Escherich G; Schmiegelow K; Sonneveld E; Pieters R; van de Ven PM; Jansen G; Assaraf YG; Kaspers GJ; Cloos J
J Hematol Oncol; 2015 May; 8():61. PubMed ID: 26022503
[TBL] [Abstract][Full Text] [Related]
20. In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.
Sorich MJ; Pottier N; Pei D; Yang W; Kager L; Stocco G; Cheng C; Panetta JC; Pui CH; Relling MV; Cheok MH; Evans WE
PLoS Med; 2008 Apr; 5(4):e83. PubMed ID: 18416598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]