BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 9920889)

  • 1. Kinetic and thermodynamic analysis of mutant type II DNA topoisomerases that cannot covalently cleave DNA.
    Morris SK; Harkins TT; Tennyson RB; Lindsley JE
    J Biol Chem; 1999 Feb; 274(6):3446-52. PubMed ID: 9920889
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Communication between the ATPase and cleavage/religation domains of human topoisomerase IIalpha.
    Bjergbaek L; Kingma P; Nielsen IS; Wang Y; Westergaard O; Osheroff N; Andersen AH
    J Biol Chem; 2000 Apr; 275(17):13041-8. PubMed ID: 10777608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis.
    Vaughn J; Huang S; Wessel I; Sorensen TK; Hsieh T; Jensen LH; Jensen PB; Sehested M; Nitiss JL
    J Biol Chem; 2005 Mar; 280(12):11920-9. PubMed ID: 15647268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ATPase reaction cycle of yeast DNA topoisomerase II. Slow rates of ATP resynthesis and P(i) release.
    Baird CL; Gordon MS; Andrenyak DM; Marecek JF; Lindsley JE
    J Biol Chem; 2001 Jul; 276(30):27893-8. PubMed ID: 11353771
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Yeast topoisomerase II is inhibited by etoposide after hydrolyzing the first ATP and before releasing the second ADP.
    Morris SK; Lindsley JE
    J Biol Chem; 1999 Oct; 274(43):30690-6. PubMed ID: 10521457
    [TBL] [Abstract][Full Text] [Related]  

  • 6. On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II.
    Lindsley JE; Wang JC
    J Biol Chem; 1993 Apr; 268(11):8096-104. PubMed ID: 8385137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalysis of ATP hydrolysis by two NH(2)-terminal fragments of yeast DNA topoisomerase II.
    Olland S; Wang JC
    J Biol Chem; 1999 Jul; 274(31):21688-94. PubMed ID: 10419479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193.
    Morris SK; Baird CL; Lindsley JE
    J Biol Chem; 2000 Jan; 275(4):2613-8. PubMed ID: 10644721
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation.
    Mueller-Planitz F; Herschlag D
    J Biol Chem; 2006 Aug; 281(33):23395-404. PubMed ID: 16782968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pre-steady-state analysis of ATP hydrolysis by Saccharomyces cerevisiae DNA topoisomerase II. 1. A DNA-dependent burst in ATP hydrolysis.
    Harkins TT; Lindsley JE
    Biochemistry; 1998 May; 37(20):7292-8. PubMed ID: 9585543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability.
    West KL; Turnbull RM; Willmore E; Lakey JH; Austin CA
    Nucleic Acids Res; 2002 Dec; 30(24):5416-24. PubMed ID: 12490710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism.
    Mueller-Planitz F; Herschlag D
    J Biol Chem; 2008 Jun; 283(25):17463-76. PubMed ID: 18403371
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Topoisomerase II drives DNA transport by hydrolyzing one ATP.
    Baird CL; Harkins TT; Morris SK; Lindsley JE
    Proc Natl Acad Sci U S A; 1999 Nov; 96(24):13685-90. PubMed ID: 10570133
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATPase domain of eukaryotic DNA topoisomerase II. Inhibition of ATPase activity by the anti-cancer drug bisdioxopiperazine and ATP/ADP-induced dimerization.
    Hu T; Sage H; Hsieh TS
    J Biol Chem; 2002 Feb; 277(8):5944-51. PubMed ID: 11850431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The DNA dependence of the ATPase activity of human DNA topoisomerase IIalpha.
    Hammonds TR; Maxwell A
    J Biol Chem; 1997 Dec; 272(51):32696-703. PubMed ID: 9405488
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identifying Lys359 as a critical residue for the ATP-dependent reactions of Drosophila DNA topoisomerase II.
    Hu T; Chang S; Hsieh T
    J Biol Chem; 1998 Apr; 273(16):9586-92. PubMed ID: 9545289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis.
    Kwon Y; Shin BS; Chung IK
    J Biol Chem; 2000 Jun; 275(24):18503-10. PubMed ID: 10764786
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pre-steady-state analysis of ATP hydrolysis by Saccharomyces cerevisiae DNA topoisomerase II. 2. Kinetic mechanism for the sequential hydrolysis of two ATP.
    Harkins TT; Lewis TJ; Lindsley JE
    Biochemistry; 1998 May; 37(20):7299-312. PubMed ID: 9585544
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases.
    Roca J; Wang JC
    Cell; 1992 Nov; 71(5):833-40. PubMed ID: 1330327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The QTK loop is essential for the communication between the N-terminal atpase domain and the central cleavage--ligation region in human topoisomerase IIalpha.
    Bendsen S; Oestergaard VH; Skouboe C; Brinch M; Knudsen BR; Andersen AH
    Biochemistry; 2009 Jul; 48(27):6508-15. PubMed ID: 19485418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.