BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 9922041)

  • 1. Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study.
    Whitehead VM; Vuchich MJ; Cooley LD; Lauer SJ; Mahoney DH; Shuster JJ; Payment C; Koch PA; Akabutu JJ; Bowen T; Kamen BA; Ravindranath Y; Emami A; Look AT; Beardsley GP; Pullen DJ; Camitta B
    Leuk Lymphoma; 1998 Nov; 31(5-6):507-19. PubMed ID: 9922041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM; Vuchich MJ; Lauer SJ; Mahoney D; Carroll AJ; Shuster JJ; Esseltine DW; Payment C; Look AT; Akabutu J
    Blood; 1992 Sep; 80(5):1316-23. PubMed ID: 1381244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM; Payment C; Cooley L; Lauer SJ; Mahoney DH; Shuster JJ; Vuchich MJ; Bernstein ML; Look AT; Pullen DJ; Camitta B
    Leukemia; 2001 Jul; 15(7):1081-8. PubMed ID: 11455977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methotrexate polyglutamate synthesis in lymphoblasts from children with acute lymphoblastic leukemia.
    Whitehead VM; Rosenblatt DS; Vuchich MJ; Beaulieu D
    Dev Pharmacol Ther; 1987; 10(6):443-8. PubMed ID: 2445535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.
    Mantadakis E; Smith AK; Hynan L; Winick NJ; Kamen BA
    J Pediatr Hematol Oncol; 2002 Nov; 24(8):636-42. PubMed ID: 12439035
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis.
    Whitehead VM; Rosenblatt DS; Vuchich MJ; Shuster JJ; Witte A; Beaulieu D
    Blood; 1990 Jul; 76(1):44-9. PubMed ID: 1694703
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trisomy of leukemic cell chromosomes 4 and 10 identifies children with B-progenitor cell acute lymphoblastic leukemia with a very low risk of treatment failure: a Pediatric Oncology Group study.
    Harris MB; Shuster JJ; Carroll A; Look AT; Borowitz MJ; Crist WM; Nitschke R; Pullen J; Steuber CP; Land VJ
    Blood; 1992 Jun; 79(12):3316-24. PubMed ID: 1596572
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
    Galpin AJ; Schuetz JD; Masson E; Yanishevski Y; Synold TW; Barredo JC; Pui CH; Relling MV; Evans WE
    Mol Pharmacol; 1997 Jul; 52(1):155-63. PubMed ID: 9224825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
    Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
    Weigand M; Frei E; Graf N; Wiessler M
    J Cancer Res Clin Oncol; 2000 Jul; 126(7):407-11. PubMed ID: 10929763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM; Shuster JJ; Vuchich MJ; Mahoney DH; Lauer SJ; Payment C; Koch PA; Cooley LD; Look AT; Pullen DJ; Camitta B
    Leukemia; 2005 Apr; 19(4):533-6. PubMed ID: 15716987
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    Buchholz B; Frei E; Eisenbarth J; Weigand M; Ludwig R
    Eur J Cancer; 1996 Nov; 32A(12):2101-7. PubMed ID: 9014752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW; Relling MV; Boyett JM; Rivera GK; Sandlund JT; Mahmoud H; Crist WM; Pui CH; Evans WE
    J Clin Invest; 1994 Nov; 94(5):1996-2001. PubMed ID: 7525652
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM; Vuchich MJ; Cooley L; Lauer SJ; Mahoney DH; Shuster JJ; Payment C; Bernstein ML; Akabutu JJ; Bowen T; Kamen BA; Watson MS; Look AT; Pullen DJ; Camitta B
    Clin Cancer Res; 1998 Jan; 4(1):183-8. PubMed ID: 9516969
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM; Krynetski EY; Schuetz JD; Yanishevski Y; Masson E; Mathew S; Raimondi S; Pui CH; Relling MV; Evans WE
    Blood; 1999 Mar; 93(5):1643-50. PubMed ID: 10029593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methotrexate pharmacology and resistance in childhood acute lymphoblastic leukemia.
    Matherly LH; Taub JW
    Leuk Lymphoma; 1996 May; 21(5-6):359-68. PubMed ID: 9172800
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methotrexate metabolism by bone marrow cells from patients with leukemia.
    Whitehead VM; Rosenblatt DS
    Adv Exp Med Biol; 1983; 163():287-303. PubMed ID: 6193691
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
    Zhang L; Taub JW; Williamson M; Wong SC; Hukku B; Pullen J; Ravindranath Y; Matherly LH
    Clin Cancer Res; 1998 Sep; 4(9):2169-77. PubMed ID: 9748136
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E; Relling MV; Synold TW; Liu Q; Schuetz JD; Sandlund JT; Pui CH; Evans WE
    J Clin Invest; 1996 Jan; 97(1):73-80. PubMed ID: 8550853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High concordance from independent studies by the Children's Cancer Group (CCG) and Pediatric Oncology Group (POG) associating favorable prognosis with combined trisomies 4, 10, and 17 in children with NCI Standard-Risk B-precursor Acute Lymphoblastic Leukemia: a Children's Oncology Group (COG) initiative.
    Sutcliffe MJ; Shuster JJ; Sather HN; Camitta BM; Pullen J; Schultz KR; Borowitz MJ; Gaynon PS; Carroll AJ; Heerema NA
    Leukemia; 2005 May; 19(5):734-40. PubMed ID: 15789069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.