BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 9925294)

  • 1. Structural basis for selective inhibition of COX-2 by nimesulide.
    Fabiola GF; Pattabhi V; Nagarajan K
    Bioorg Med Chem; 1998 Dec; 6(12):2337-44. PubMed ID: 9925294
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Automated docking and molecular dynamics simulations of nimesulide in the cyclooxygenase active site of human prostaglandin-endoperoxide synthase-2 (COX-2).
    García-Nieto R; Pérez C; Gago F
    J Comput Aided Mol Des; 2000 Feb; 14(2):147-60. PubMed ID: 10721503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rationale for the observed COX-2/COX-1 selectivity of celecoxib from Monte Carlo simulations.
    Price ML; Jorgensen WL
    Bioorg Med Chem Lett; 2001 Jun; 11(12):1541-4. PubMed ID: 11412976
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors.
    Park CH; Siomboing X; Yous S; Gressier B; Luyckx M; Chavatte P
    Eur J Med Chem; 2002 Jun; 37(6):461-8. PubMed ID: 12204472
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural approach for COX-2 inhibition.
    Michaux C; Charlier C
    Mini Rev Med Chem; 2004 Aug; 4(6):603-15. PubMed ID: 15279594
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of nimesulide and indometacin on COX-1 and COX-2: a comparative study.
    de Leval X; Dogné JM; Neven P; Labasse A; Delarge J; Reginster JY; Henrotin Y
    J Pharm Belg; 1999; 54(3):89-90. PubMed ID: 10431478
    [TBL] [Abstract][Full Text] [Related]  

  • 7. COX in a crystal ball: current status and future promise of prostaglandin research.
    FitzGerald GA; Loll P
    J Clin Invest; 2001 Jun; 107(11):1335-7. PubMed ID: 11390412
    [No Abstract]   [Full Text] [Related]  

  • 8. In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview.
    Famaey JP
    Inflamm Res; 1997 Nov; 46(11):437-46. PubMed ID: 9427063
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structure of mammalian cyclooxygenases.
    Garavito RM; Mulichak AM
    Annu Rev Biophys Biomol Struct; 2003; 32():183-206. PubMed ID: 12574066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.
    Gierse JK; McDonald JJ; Hauser SD; Rangwala SH; Koboldt CM; Seibert K
    J Biol Chem; 1996 Jun; 271(26):15810-4. PubMed ID: 8663121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models.
    Palomer A; Cabré F; Pascual J; Campos J; Trujillo MA; Entrena A; Gallo MA; García L; Mauleón D; Espinosa A
    J Med Chem; 2002 Mar; 45(7):1402-11. PubMed ID: 11906281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of the dynamic mechanism of ligand binding to cyclooxygenase.
    Llorens O; Perez JJ; Palomer A; Mauleon D
    Bioorg Med Chem Lett; 1999 Oct; 9(19):2779-84. PubMed ID: 10522690
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of inhibition of novel COX-2 inhibitors.
    Gierse J; Kurumbail R; Walker M; Hood B; Monahan J; Pawlitz J; Stegeman R; Stevens A; Kiefer J; Koboldt C; Moreland K; Rowlinson S; Marnett L; Pierce J; Carter J; Talley J; Isakson P; Seibert K
    Adv Exp Med Biol; 2002; 507():365-9. PubMed ID: 12664611
    [No Abstract]   [Full Text] [Related]  

  • 14. Computer-aided design of selective COX-2 inhibitors: comparative molecular field analysis, comparative molecular similarity indices analysis, and docking studies of some 1,2-diarylimidazole derivatives.
    Desiraju GR; Gopalakrishnan B; Jetti RK; Nagaraju A; Raveendra D; Sarma JA; Sobhia ME; Thilagavathi R
    J Med Chem; 2002 Oct; 45(22):4847-57. PubMed ID: 12383010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis.
    Ermondi G; Caron G; Lawrence R; Longo D
    J Comput Aided Mol Des; 2004 Nov; 18(11):683-96. PubMed ID: 15865061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular model of the interaction between nimesulide and human cyclooxygenase-2.
    García-Nieto R; Pérez C; Checa A; Gago F
    Rheumatology (Oxford); 1999 May; 38 Suppl 1():14-8. PubMed ID: 10369401
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformationally restricted 3,4-diarylfuranones (2,3a,4,5-tetrahydronaphthofuranones) as selective cyclooxygenase-2 inhibitors.
    Pal M; Rao Veeramaneni V; Nagabelli M; Rao Kalleda S; Misra P; Rao Casturi S; Rao Yeleswarapu K
    Bioorg Med Chem Lett; 2003 May; 13(10):1639-43. PubMed ID: 12729631
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins.
    Garavito RM; DeWitt DL
    Biochim Biophys Acta; 1999 Nov; 1441(2-3):278-87. PubMed ID: 10570255
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclooxygenase 2 inhibitors: discovery, selectivity and the future.
    Marnett LJ; Kalgutkar AS
    Trends Pharmacol Sci; 1999 Nov; 20(11):465-9. PubMed ID: 10542447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.