213 related articles for article (PubMed ID: 9925294)
21. Differential binding mode of diverse cyclooxygenase inhibitors.
Llorens O; Perez JJ; Palomer A; Mauleon D
J Mol Graph Model; 2002 Mar; 20(5):359-71. PubMed ID: 11885959
[TBL] [Abstract][Full Text] [Related]
22. Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere.
Habeeb AG; Praveen Rao PN; Knaus EE
J Med Chem; 2001 Aug; 44(18):3039-42. PubMed ID: 11520213
[TBL] [Abstract][Full Text] [Related]
23. Spectral and crystallographic study of pyridinic analogues of nimesulide: determination of the active form of methanesulfonamides as COX-2 selective inhibitors.
Julémont F; de Leval X; Michaux C; Damas J; Charlier C; Durant F; Pirotte B; Dogné JM
J Med Chem; 2002 Nov; 45(23):5182-5. PubMed ID: 12408728
[TBL] [Abstract][Full Text] [Related]
24. Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2.
Luong C; Miller A; Barnett J; Chow J; Ramesha C; Browner MF
Nat Struct Biol; 1996 Nov; 3(11):927-33. PubMed ID: 8901870
[TBL] [Abstract][Full Text] [Related]
25. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity.
Lazer ES; Miao CK; Cywin CL; Sorcek R; Wong HC; Meng Z; Potocki I; Hoermann M; Snow RJ; Tschantz MA; Kelly TA; McNeil DW; Coutts SJ; Churchill L; Graham AG; David E; Grob PM; Engel W; Meier H; Trummlitz G
J Med Chem; 1997 Mar; 40(6):980-9. PubMed ID: 9083488
[TBL] [Abstract][Full Text] [Related]
26. [Studied on docking of 5,6-diaryl-2,3-dihydro-1-pyrrolizinone derivatives with cyclooxygenase].
Zhao LQ; Hu YD; Yuan Y; Zhang T; Zhang SF; Li S
Yao Xue Xue Bao; 2001 Jun; 36(6):415-8. PubMed ID: 12585123
[TBL] [Abstract][Full Text] [Related]
27. 4-(4-cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as selective cyclooxygenase-2 inhibitors: enhancement of the selectivity by introduction of a fluorine atom and identification of a potent, highly selective, and orally active COX-2 inhibitor JTE-522(1).
Hashimoto H; Imamura K; Haruta J; Wakitani K
J Med Chem; 2002 Mar; 45(7):1511-7. PubMed ID: 11906292
[TBL] [Abstract][Full Text] [Related]
28. Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition.
Marnett LJ; Rowlinson SW; Goodwin DC; Kalgutkar AS; Lanzo CA
J Biol Chem; 1999 Aug; 274(33):22903-6. PubMed ID: 10438452
[No Abstract] [Full Text] [Related]
29. Estimation of binding affinities for celecoxib analogues with COX-2 via Monte Carlo-extended linear response.
Wesolowski SS; Jorgensen WL
Bioorg Med Chem Lett; 2002 Feb; 12(3):267-70. PubMed ID: 11814774
[TBL] [Abstract][Full Text] [Related]
30. Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors.
Singh SK; Vobbalareddy S; Shivaramakrishna S; Krishnamraju A; Rajjak SA; Casturi SR; Akhila V; Rao YK
Bioorg Med Chem Lett; 2004 Apr; 14(7):1683-8. PubMed ID: 15026050
[TBL] [Abstract][Full Text] [Related]
31. Structure-based QSAR study on differential inhibition of human prostaglandin endoperoxide H synthase-2 (COX-2) by nonsteroidal anti-inflammatory drugs.
Pouplana R; Lozano JJ; Pérez C; Ruiz J
J Comput Aided Mol Des; 2002 Oct; 16(10):683-709. PubMed ID: 12650588
[TBL] [Abstract][Full Text] [Related]
32. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
[TBL] [Abstract][Full Text] [Related]
33. Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs.
Steiner AA; Li S; Llanos-Q J; Blatteis CM
Neuroimmunomodulation; 2001; 9(5):263-75. PubMed ID: 11964521
[TBL] [Abstract][Full Text] [Related]
34. Conversion of prostaglandin G/H synthase-1 into an enzyme sensitive to PGHS-2-selective inhibitors by a double His513 --> Arg and Ile523 --> val mutation.
Wong E; Bayly C; Waterman HL; Riendeau D; Mancini JA
J Biol Chem; 1997 Apr; 272(14):9280-6. PubMed ID: 9083063
[TBL] [Abstract][Full Text] [Related]
35. COX-2 selectivity and inflammatory processes.
van Ryn J; Trummlitz G; Pairet M
Curr Med Chem; 2000 Nov; 7(11):1145-61. PubMed ID: 11032964
[TBL] [Abstract][Full Text] [Related]
36. Interaction of PGH synthase isozymes-1 and -2 with nonsteroidal anti-inflammatory drugs.
Smith WL; Meade EA; Dewitt DL
Adv Exp Med Biol; 1997; 400A():189-96. PubMed ID: 9547557
[No Abstract] [Full Text] [Related]
37. Optimization and validation of a docking-scoring protocol; application to virtual screening for COX-2 inhibitors.
Mozziconacci JC; Arnoult E; Bernard P; Do QT; Marot C; Morin-Allory L
J Med Chem; 2005 Feb; 48(4):1055-68. PubMed ID: 15715473
[TBL] [Abstract][Full Text] [Related]
38. Human and rat cyclooxygenases are pharmacologically distinct.
Ramesha CS
Adv Exp Med Biol; 1997; 407():67-71. PubMed ID: 9321933
[No Abstract] [Full Text] [Related]
39. Thalidomide and its analogues as cyclooxygenase inhibitors.
Noguchi T; Shimazawa R; Nagasawa K; Hashimoto Y
Bioorg Med Chem Lett; 2002 Apr; 12(7):1043-6. PubMed ID: 11909713
[TBL] [Abstract][Full Text] [Related]
40. Interactions of some PGHS-2 selective inhibitors with the PGHS-1: an automated docking study by BioDock.
Pedretti A; Villa AM; Villa L; Vistoli G
Farmaco; 1997; 52(6-7):487-91. PubMed ID: 9372601
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
