BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

359 related articles for article (PubMed ID: 9933596)

  • 1. The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
    Nadeau OW; Domanski P; Usacheva A; Uddin S; Platanias LC; Pitha P; Raz R; Levy D; Majchrzak B; Fish E; Colamonici OR
    J Biol Chem; 1999 Feb; 274(7):4045-52. PubMed ID: 9933596
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells.
    Russell-Harde D; Wagner TC; Rani MR; Vogel D; Colamonici O; Ransohoff RM; Majchrzak B; Fish E; Perez HD; Croze E
    J Biol Chem; 2000 Aug; 275(31):23981-5. PubMed ID: 10825167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.
    Novick D; Nabioullin RR; Ragsdale W; McKenna S; Weiser W; Garone L; Burkins C; Kim SH; Rubinstein M; Tepper MA; Arulanandam AR
    J Interferon Cytokine Res; 2000 Nov; 20(11):971-82. PubMed ID: 11096454
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein.
    Yan H; Krishnan K; Greenlund AC; Gupta S; Lim JT; Schreiber RD; Schindler CW; Krolewski JJ
    EMBO J; 1996 Mar; 15(5):1064-74. PubMed ID: 8605876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.
    Radaeva S; Jaruga B; Kim WH; Heller T; Liang TJ; Gao B
    Biochem J; 2004 Apr; 379(Pt 1):199-208. PubMed ID: 14690454
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3.
    Martinez-Moczygemba M; Gutch MJ; French DL; Reich NC
    J Biol Chem; 1997 Aug; 272(32):20070-6. PubMed ID: 9242679
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling.
    Li X; Leung S; Kerr IM; Stark GR
    Mol Cell Biol; 1997 Apr; 17(4):2048-56. PubMed ID: 9121453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
    Nguyen VP; Saleh AZ; Arch AE; Yan H; Piazza F; Kim J; Krolewski JJ
    J Biol Chem; 2002 Mar; 277(12):9713-21. PubMed ID: 11786546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation.
    Basu L; Yang CH; Murti A; Garcia JV; Croze E; Constantinescu SN; Mullersman JE; Pfeffer LM
    Virology; 1998 Mar; 242(1):14-21. PubMed ID: 9501047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Configuration of the interferon-alpha/beta receptor complex determines the context of the biological response.
    Ghislain J; Sussman G; Goelz S; Ling LE; Fish EN
    J Biol Chem; 1995 Sep; 270(37):21785-92. PubMed ID: 7665599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha.
    Li X; Leung S; Qureshi S; Darnell JE; Stark GR
    J Biol Chem; 1996 Mar; 271(10):5790-4. PubMed ID: 8621447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.
    Li S; Labrecque S; Gauzzi MC; Cuddihy AR; Wong AH; Pellegrini S; Matlashewski GJ; Koromilas AE
    Oncogene; 1999 Oct; 18(42):5727-37. PubMed ID: 10523853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells.
    Wagner TC; Velichko S; Vogel D; Rani MR; Leung S; Ransohoff RM; Stark GR; Perez HD; Croze E
    J Biol Chem; 2002 Jan; 277(2):1493-9. PubMed ID: 11682488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription.
    Eilers A; Kanda K; Klose B; Krolewski J; Decker T
    Cell Growth Differ; 1996 Jun; 7(6):833-40. PubMed ID: 8780896
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction.
    Parisien JP; Lau JF; Rodriguez JJ; Ulane CM; Horvath CM
    J Virol; 2002 May; 76(9):4190-8. PubMed ID: 11932384
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.
    Wong LH; Krauer KG; Hatzinisiriou I; Estcourt MJ; Hersey P; Tam ND; Edmondson S; Devenish RJ; Ralph SJ
    J Biol Chem; 1997 Nov; 272(45):28779-85. PubMed ID: 9353349
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
    Colamonici O; Yan H; Domanski P; Handa R; Smalley D; Mullersman J; Witte M; Krishnan K; Krolewski J
    Mol Cell Biol; 1994 Dec; 14(12):8133-42. PubMed ID: 7526154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dimerization of a chimeric CD4-interferon-alpha receptor reconstitutes the signaling events preceding STAT phosphorylation.
    Krishnan K; Yan H; Lim JT; Krolewski JJ
    Oncogene; 1996 Jul; 13(1):125-33. PubMed ID: 8700538
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity.
    Lee CK; Bluyssen HA; Levy DE
    J Biol Chem; 1997 Aug; 272(35):21872-7. PubMed ID: 9268319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3.
    Qureshi SA; Salditt-Georgieff M; Darnell JE
    Proc Natl Acad Sci U S A; 1995 Apr; 92(9):3829-33. PubMed ID: 7537377
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.