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5. Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells. Rusyn I; Kadiiska MB; Dikalova A; Kono H; Yin M; Tsuchiya K; Mason RP; Peters JM; Gonzalez FJ; Segal BH; Holland SM; Thurman RG Mol Pharmacol; 2001 Apr; 59(4):744-50. PubMed ID: 11259618 [TBL] [Abstract][Full Text] [Related]
6. Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators. Rusyn I; Rose ML; Bojes HK; Thurman RG Antioxid Redox Signal; 2000; 2(3):607-21. PubMed ID: 11229371 [TBL] [Abstract][Full Text] [Related]
7. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase. Woods CG; Burns AM; Maki A; Bradford BU; Cunningham ML; Connor HD; Kadiiska MB; Mason RP; Peters JM; Rusyn I Free Radic Biol Med; 2007 Feb; 42(3):335-42. PubMed ID: 17210446 [TBL] [Abstract][Full Text] [Related]
8. Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Rose ML; Germolec DR; Schoonhoven R; Thurman RG Carcinogenesis; 1997 Aug; 18(8):1453-6. PubMed ID: 9276615 [TBL] [Abstract][Full Text] [Related]
9. Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Peters JM; Rusyn I; Rose ML; Gonzalez FJ; Thurman RG Carcinogenesis; 2000 Apr; 21(4):823-6. PubMed ID: 10753222 [TBL] [Abstract][Full Text] [Related]
10. Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression. Woods CG; Kosyk O; Bradford BU; Ross PK; Burns AM; Cunningham ML; Qu P; Ibrahim JG; Rusyn I Toxicol Appl Pharmacol; 2007 Dec; 225(3):267-77. PubMed ID: 17950772 [TBL] [Abstract][Full Text] [Related]
11. Role of Kupffer cells and oxidants in signaling peroxisome proliferator-induced hepatocyte proliferation. Rose ML; Rusyn I; Bojes HK; Belyea J; Cattley RC; Thurman RG Mutat Res; 2000 Mar; 448(2):179-92. PubMed ID: 10725471 [No Abstract] [Full Text] [Related]
12. Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643. Rose ML; Cattley RC; Dunn C; Wong V; Li X; Thurman RG Carcinogenesis; 1999 Nov; 20(11):2075-81. PubMed ID: 10545408 [TBL] [Abstract][Full Text] [Related]
14. Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes. Parzefall W; Berger W; Kainzbauer E; Teufelhofer O; Schulte-Hermann R; Thurman RG Carcinogenesis; 2001 Mar; 22(3):519-23. PubMed ID: 11238195 [TBL] [Abstract][Full Text] [Related]
15. Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643. Conway JG; Tomaszewski KE; Olson MJ; Cattley RC; Marsman DS; Popp JA Carcinogenesis; 1989 Mar; 10(3):513-9. PubMed ID: 2924396 [TBL] [Abstract][Full Text] [Related]
16. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Marsman DS; Cattley RC; Conway JG; Popp JA Cancer Res; 1988 Dec; 48(23):6739-44. PubMed ID: 3180084 [TBL] [Abstract][Full Text] [Related]
17. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. Woods CG; Burns AM; Bradford BU; Ross PK; Kosyk O; Swenberg JA; Cunningham ML; Rusyn I Toxicol Sci; 2007 Aug; 98(2):366-74. PubMed ID: 17483499 [TBL] [Abstract][Full Text] [Related]
19. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)? Melnick RL Environ Health Perspect; 2001 May; 109(5):437-42. PubMed ID: 11401753 [TBL] [Abstract][Full Text] [Related]
20. Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells. Tsutsui T; Watanabe E; Barrett JC Carcinogenesis; 1993 Apr; 14(4):611-8. PubMed ID: 8472324 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]