383 related articles for article (PubMed ID: 9934856)
1. Expression of the inactive C145A mutant human O6-alkylguanine-DNA alkyltransferase in E.coli increases cell killing and mutations by N-methyl-N'-nitro-N-nitrosoguanidine.
Edara S; Kanugula S; Pegg AE
Carcinogenesis; 1999 Jan; 20(1):103-8. PubMed ID: 9934856
[TBL] [Abstract][Full Text] [Related]
2. Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Goodtzova K; Kanugula S; Edara S; Pegg AE
Biochemistry; 1998 Sep; 37(36):12489-95. PubMed ID: 9730821
[TBL] [Abstract][Full Text] [Related]
3. Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts.
Lukash LL; Boldt J; Pegg AE; Dolan ME; Maher VM; McCormick JJ
Mutat Res; 1991; 250(1-2):397-409. PubMed ID: 1944354
[TBL] [Abstract][Full Text] [Related]
4. Amino acid residues affecting the activity and stability of human O6-alkylguanine-DNA alkyltransferase.
Crone TM; Goodtzova K; Pegg AE
Mutat Res; 1996 May; 363(1):15-25. PubMed ID: 8632775
[TBL] [Abstract][Full Text] [Related]
5. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.
Crone TM; Pegg AE
Cancer Res; 1993 Oct; 53(20):4750-3. PubMed ID: 8402653
[TBL] [Abstract][Full Text] [Related]
6. Function of domains of human O6-alkylguanine-DNA alkyltransferase.
Fang Q; Kanugula S; Pegg AE
Biochemistry; 2005 Nov; 44(46):15396-405. PubMed ID: 16285744
[TBL] [Abstract][Full Text] [Related]
7. Alteration of the conserved residue tyrosine-158 to histidine renders human O6-alkylguanine-DNA alkyltransferase insensitive to the inhibitor O6-benzylguanine.
Xu-Welliver M; Leitão J; Kanugula S; Pegg AE
Cancer Res; 1999 Apr; 59(7):1514-9. PubMed ID: 10197622
[TBL] [Abstract][Full Text] [Related]
8. Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine.
Xu-Welliver M; Kanugula S; Pegg AE
Cancer Res; 1998 May; 58(9):1936-45. PubMed ID: 9581836
[TBL] [Abstract][Full Text] [Related]
9. Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.
Fang Q; Kanugula S; Tubbs JL; Tainer JA; Pegg AE
J Biol Chem; 2010 Mar; 285(11):8185-95. PubMed ID: 20026607
[TBL] [Abstract][Full Text] [Related]
10. Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine.
Kanugula S; Goodtzova K; Edara S; Pegg AE
Biochemistry; 1995 May; 34(21):7113-9. PubMed ID: 7766621
[TBL] [Abstract][Full Text] [Related]
11. O6-alkylguanine-DNA alkyltransferase has opposing effects in modulating the genotoxicity of dibromomethane and bromomethyl acetate.
Liu L; Williams KM; Guengerich FP; Pegg AE
Chem Res Toxicol; 2004 Jun; 17(6):742-52. PubMed ID: 15206895
[TBL] [Abstract][Full Text] [Related]
12. Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.
von Hofe E; Fairbairn L; Margison GP
Proc Natl Acad Sci U S A; 1992 Dec; 89(23):11199-203. PubMed ID: 1454799
[TBL] [Abstract][Full Text] [Related]
13. Conserved residue lysine165 is essential for the ability of O6-alkylguanine-DNA alkyltransferase to react with O6-benzylguanine.
Xu-Welliver M; Kanugula S; Loktionova NA; Crone TM; Pegg AE
Biochem J; 2000 Apr; 347(Pt 2):527-34. PubMed ID: 10749683
[TBL] [Abstract][Full Text] [Related]
14. Alkylation damage, DNA repair and mutagenesis in human cells.
Maher VM; Domoradzki J; Bhattacharyya NP; Tsujimura T; Corner RC; McCormick JJ
Mutat Res; 1990; 233(1-2):235-45. PubMed ID: 2233805
[TBL] [Abstract][Full Text] [Related]
15. The role of human O(6)-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli.
Liu H; Xu-Welliver M; Pegg AE
Mutat Res; 2000 Jul; 452(1):1-10. PubMed ID: 10894884
[TBL] [Abstract][Full Text] [Related]
16. DNA mismatch repair mutants do not increase N-methyl-N'-nitro-N-nitrosoguanidine tolerance in O6-methylguanine DNA methyltransferase-deficient yeast cells.
Xiao W; Rathgeber L; Fontanie T; Bawa S
Carcinogenesis; 1995 Aug; 16(8):1933-9. PubMed ID: 7634424
[TBL] [Abstract][Full Text] [Related]
17. Role of codon 160 in the sensitivity of human O6-alkylguanine-DNA alkyltransferase to O6-benzylguanine.
Xu-Welliver M; Leitão J; Kanugula S; Meehan WJ; Pegg AE
Biochem Pharmacol; 1999 Oct; 58(8):1279-85. PubMed ID: 10487529
[TBL] [Abstract][Full Text] [Related]
18. Role of alkyltransferase-like (ATL) protein in repair of methylated DNA lesions in Thermus thermophilus.
Onodera T; Morino K; Tokishita S; Morita R; Masui R; Kuramitsu S; Ohta T
Mutagenesis; 2011 Mar; 26(2):303-8. PubMed ID: 21059809
[TBL] [Abstract][Full Text] [Related]
19. Human O(6)-alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes.
Abril N; Luque-Romero FL; Christians FC; Encell LP; Loeb LA; Pueyo C
Carcinogenesis; 1999 Nov; 20(11):2089-94. PubMed ID: 10545410
[TBL] [Abstract][Full Text] [Related]
20. Enhanced in vivo repair of O(4)-methylthymine by a mutant human DNA alkyltransferase.
Encell LP; Loeb LA
Carcinogenesis; 2000 Jul; 21(7):1397-402. PubMed ID: 10874019
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
