200 related articles for article (PubMed ID: 9952300)
1. Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks.
Chernikova SB; Wells RL; Elkind MM
Radiat Res; 1999 Feb; 151(2):159-66. PubMed ID: 9952300
[TBL] [Abstract][Full Text] [Related]
2. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Wang H; Zeng ZC; Bui TA; DiBiase SJ; Qin W; Xia F; Powell SN; Iliakis G
Cancer Res; 2001 Jan; 61(1):270-7. PubMed ID: 11196174
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.
Sarkaria JN; Tibbetts RS; Busby EC; Kennedy AP; Hill DE; Abraham RT
Cancer Res; 1998 Oct; 58(19):4375-82. PubMed ID: 9766667
[TBL] [Abstract][Full Text] [Related]
4. Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines.
Sak A; Stuschke M; Wurm R; Schroeder G; Sinn B; Wolf G; Budach V
Cancer Res; 2002 Nov; 62(22):6621-4. PubMed ID: 12438258
[TBL] [Abstract][Full Text] [Related]
5. Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.
Okayasu R; Suetomi K; Ullrich RL
Radiat Res; 1998 May; 149(5):440-5. PubMed ID: 9588354
[TBL] [Abstract][Full Text] [Related]
6. Relationship between the radiosensitizing effect of wortmannin, DNA double-strand break rejoining, and p21WAF1 induction in human normal and tumor-derived cells.
Mirzayans R; Pollock S; Scott A; Enns L; Andrais B; Murray D
Mol Carcinog; 2004 Mar; 39(3):164-72. PubMed ID: 14991746
[TBL] [Abstract][Full Text] [Related]
7. Wortmannin enhances the induction of micronuclei by low and high LET radiation.
Oliveira NG; Castro M; Rodrigues AS; Gonçalves IC; Gil OM; Fernandes AP; Toscano-Rico JM; Rueff J
Mutagenesis; 2003 Jan; 18(1):37-44. PubMed ID: 12473733
[TBL] [Abstract][Full Text] [Related]
8. SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization.
Ismail IH; Mårtensson S; Moshinsky D; Rice A; Tang C; Howlett A; McMahon G; Hammarsten O
Oncogene; 2004 Jan; 23(4):873-82. PubMed ID: 14661061
[TBL] [Abstract][Full Text] [Related]
9. DNA-PK: the major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway.
Hashimoto M; Rao S; Tokuno O; Yamamoto K; Takata M; Takeda S; Utsumi H
J Radiat Res; 2003 Jun; 44(2):151-9. PubMed ID: 13678345
[TBL] [Abstract][Full Text] [Related]
10. Effect of Wortmannin on the repair profiles of DNA double-strand breaks in the whole genome and in interstitial telomeric sequences of Chinese hamster cells.
Losada R; Rivero MT; Slijepcevic P; Goyanes V; Fernández JL
Mutat Res; 2005 Feb; 570(1):119-28. PubMed ID: 15680409
[TBL] [Abstract][Full Text] [Related]
11. Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.
Rosenzweig KE; Youmell MB; Palayoor ST; Price BD
Clin Cancer Res; 1997 Jul; 3(7):1149-56. PubMed ID: 9815794
[TBL] [Abstract][Full Text] [Related]
12. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
Veuger SJ; Curtin NJ; Richardson CJ; Smith GC; Durkacz BW
Cancer Res; 2003 Sep; 63(18):6008-15. PubMed ID: 14522929
[TBL] [Abstract][Full Text] [Related]
13. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
Wang H; Guan J; Wang H; Perrault AR; Wang Y; Iliakis G
Cancer Res; 2001 Dec; 61(23):8554-63. PubMed ID: 11731442
[TBL] [Abstract][Full Text] [Related]
14. DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus.
DiBiase SJ; Zeng ZC; Chen R; Hyslop T; Curran WJ; Iliakis G
Cancer Res; 2000 Mar; 60(5):1245-53. PubMed ID: 10728683
[TBL] [Abstract][Full Text] [Related]
15. Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin.
Christodoulopoulos G; Muller C; Salles B; Kazmi R; Panasci L
Cancer Res; 1998 May; 58(9):1789-92. PubMed ID: 9581813
[TBL] [Abstract][Full Text] [Related]
16. A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation.
Kim CH; Park SJ; Lee SH
J Pharmacol Exp Ther; 2002 Nov; 303(2):753-9. PubMed ID: 12388662
[TBL] [Abstract][Full Text] [Related]
17. Interactive effects of inhibitors of poly(ADP-ribose) polymerase and DNA-dependent protein kinase on cellular responses to DNA damage.
Boulton S; Kyle S; Durkacz BW
Carcinogenesis; 1999 Feb; 20(2):199-203. PubMed ID: 10069454
[TBL] [Abstract][Full Text] [Related]
18. Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants.
Asaad NA; Zeng ZC; Guan J; Thacker J; Iliakis G
Oncogene; 2000 Nov; 19(50):5788-800. PubMed ID: 11126366
[TBL] [Abstract][Full Text] [Related]
19. Interactive competition between homologous recombination and non-homologous end joining.
Allen C; Halbrook J; Nickoloff JA
Mol Cancer Res; 2003 Oct; 1(12):913-20. PubMed ID: 14573792
[TBL] [Abstract][Full Text] [Related]
20. DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs.
Shinohara ET; Geng L; Tan J; Chen H; Shir Y; Edwards E; Halbrook J; Kesicki EA; Kashishian A; Hallahan DE
Cancer Res; 2005 Jun; 65(12):4987-92. PubMed ID: 15958537
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]