312 related articles for article (PubMed ID: 9971776)
1. Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking.
Mangasarian A; Piguet V; Wang JK; Chen YL; Trono D
J Virol; 1999 Mar; 73(3):1964-73. PubMed ID: 9971776
[TBL] [Abstract][Full Text] [Related]
2. Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.
Swigut T; Iafrate AJ; Muench J; Kirchhoff F; Skowronski J
J Virol; 2000 Jun; 74(12):5691-701. PubMed ID: 10823877
[TBL] [Abstract][Full Text] [Related]
3. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
Greenberg ME; Iafrate AJ; Skowronski J
EMBO J; 1998 May; 17(10):2777-89. PubMed ID: 9582271
[TBL] [Abstract][Full Text] [Related]
4. Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif.
Coleman SH; Madrid R; Van Damme N; Mitchell RS; Bouchet J; Servant C; Pillai S; Benichou S; Guatelli JC
J Virol; 2006 Feb; 80(4):1837-49. PubMed ID: 16439540
[TBL] [Abstract][Full Text] [Related]
5. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity.
Craig HM; Pandori MW; Guatelli JC
Proc Natl Acad Sci U S A; 1998 Sep; 95(19):11229-34. PubMed ID: 9736718
[TBL] [Abstract][Full Text] [Related]
6. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.
Greenberg M; DeTulleo L; Rapoport I; Skowronski J; Kirchhausen T
Curr Biol; 1998 Nov; 8(22):1239-42. PubMed ID: 9811611
[TBL] [Abstract][Full Text] [Related]
7. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
Bresnahan PA; Yonemoto W; Ferrell S; Williams-Herman D; Geleziunas R; Greene WC
Curr Biol; 1998 Nov; 8(22):1235-8. PubMed ID: 9811606
[TBL] [Abstract][Full Text] [Related]
8. The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail.
Wonderlich ER; Williams M; Collins KL
J Biol Chem; 2008 Feb; 283(6):3011-3022. PubMed ID: 18073204
[TBL] [Abstract][Full Text] [Related]
9. Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.
Le Gall S; Buseyne F; Trocha A; Walker BD; Heard JM; Schwartz O
J Virol; 2000 Oct; 74(19):9256-66. PubMed ID: 10982373
[TBL] [Abstract][Full Text] [Related]
10. Hck SH3 domain-dependent abrogation of Nef-induced class 1 MHC down-regulation.
Chang AH; O'Shaughnessy MV; Jirik FR
Eur J Immunol; 2001 Aug; 31(8):2382-7. PubMed ID: 11500821
[TBL] [Abstract][Full Text] [Related]
11. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.
Stoddart CA; Geleziunas R; Ferrell S; Linquist-Stepps V; Moreno ME; Bare C; Xu W; Yonemoto W; Bresnahan PA; McCune JM; Greene WC
J Virol; 2003 Feb; 77(3):2124-33. PubMed ID: 12525647
[TBL] [Abstract][Full Text] [Related]
12. Nef-mediated clathrin-coated pit formation.
Foti M; Mangasarian A; Piguet V; Lew DP; Krause KH; Trono D; Carpentier JL
J Cell Biol; 1997 Oct; 139(1):37-47. PubMed ID: 9314527
[TBL] [Abstract][Full Text] [Related]
13. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis.
Lock M; Greenberg ME; Iafrate AJ; Swigut T; Muench J; Kirchhoff F; Shohdy N; Skowronski J
EMBO J; 1999 May; 18(10):2722-33. PubMed ID: 10329619
[TBL] [Abstract][Full Text] [Related]
14. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
Schindler M; Würfl S; Benaroch P; Greenough TC; Daniels R; Easterbrook P; Brenner M; Münch J; Kirchhoff F
J Virol; 2003 Oct; 77(19):10548-56. PubMed ID: 12970439
[TBL] [Abstract][Full Text] [Related]
15. HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.
Jin YJ; Cai CY; Zhang X; Zhang HT; Hirst JA; Burakoff SJ
J Immunol; 2005 Sep; 175(5):3157-64. PubMed ID: 16116206
[TBL] [Abstract][Full Text] [Related]
16. Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.
Dikeakos JD; Atkins KM; Thomas L; Emert-Sedlak L; Byeon IJ; Jung J; Ahn J; Wortman MD; Kukull B; Saito M; Koizumi H; Williamson DM; Hiyoshi M; Barklis E; Takiguchi M; Suzu S; Gronenborn AM; Smithgall TE; Thomas G
Mol Biol Cell; 2010 Oct; 21(19):3279-92. PubMed ID: 20702582
[TBL] [Abstract][Full Text] [Related]
17. The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors.
Piguet V; Schwartz O; Le Gall S; Trono D
Immunol Rev; 1999 Apr; 168():51-63. PubMed ID: 10399064
[TBL] [Abstract][Full Text] [Related]
18. The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner.
Casartelli N; Giolo G; Neri F; Haller C; Potestà M; Rossi P; Fackler OT; Doria M
J Gen Virol; 2006 Aug; 87(Pt 8):2291-2296. PubMed ID: 16847125
[TBL] [Abstract][Full Text] [Related]
19. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.
Schwartz O; Maréchal V; Le Gall S; Lemonnier F; Heard JM
Nat Med; 1996 Mar; 2(3):338-42. PubMed ID: 8612235
[TBL] [Abstract][Full Text] [Related]
20. An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex.
Singh RK; Lau D; Noviello CM; Ghosh P; Guatelli JC
PLoS One; 2009 Dec; 4(12):e8364. PubMed ID: 20020046
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
