122 related articles for article (PubMed ID: 9972255)
1. Tryptophan pyrolysis products, Trp-P-1 and Trp-P-2 induce apoptosis in primary cultured rat hepatocytes.
Ashida H; Shiotani B; Adachi H; Hashimoto T; Kanazawa K; Danno G
Biosci Biotechnol Biochem; 1998 Nov; 62(11):2283-7. PubMed ID: 9972255
[TBL] [Abstract][Full Text] [Related]
2. The heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole induces apoptosis in cocultures of rat parenchymal and nonparenchymal liver cells.
Ashida H; Kihara K; Nonaka Y; Fukuda I; Shiotani B; Hashimoto T
Toxicol Appl Pharmacol; 2001 Nov; 177(1):59-67. PubMed ID: 11708901
[TBL] [Abstract][Full Text] [Related]
3. Detection of biomarkers for apoptosis in rat liver after perfusion with 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1).
Ashida H; Kihara K; Shiotani B; Hashimoto T; Kanazawa K; Danno G
Biosci Biotechnol Biochem; 2000 Sep; 64(9):2021-4. PubMed ID: 11055418
[TBL] [Abstract][Full Text] [Related]
4. Mutagenic activation of 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole(Trp-P-1) and 3-amino-1-methyl-5H-pyrido(4,3-b)indole (Trp-P-2) by primary cultures of adult rat hepatocytes: effect of Aroclor induction in vitro.
Decloître F; Hamon G; Martin M; Thybaud-Lambay V
Mutat Res; 1984; 137(2-3):123-32. PubMed ID: 6433191
[TBL] [Abstract][Full Text] [Related]
5. 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces apoptosis in rat splenocytes and thymocytes by different mechanisms.
Hashimoto T; Ashida H; Sano T; Furuyashiki T; Shiotani B; Kanazawa K; Danno G
Mutat Res; 2000 Dec; 457(1-2):57-67. PubMed ID: 11106798
[TBL] [Abstract][Full Text] [Related]
6. Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma-carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells.
Uezono T; Maruyama W; Matsubara K; Naoi M; Shimizu K; Saito O; Ogawa K; Mizukami H; Hayase N; Shiono H
J Neural Transm (Vienna); 2001; 108(8-9):943-53. PubMed ID: 11716147
[TBL] [Abstract][Full Text] [Related]
7. Evoking cytochrome P450 1A activity interferes with apoptosis induced by 3-amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) in rat hepatocytes under the ex vivo system.
Shiotani B; Nonaka Y; Kanazawa K; Danno G; Ashida H
Biosci Biotechnol Biochem; 2002 Feb; 66(2):356-62. PubMed ID: 11999409
[TBL] [Abstract][Full Text] [Related]
8. DNA-damaging carcinogen 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces apoptosis via caspase-9 in primary cultured rat hepatocytes.
Shiotani B; Nonaka Y; Hashimoto T; Kihara K; Kanazawa K; Danno G; Ashida H
Carcinogenesis; 2001 May; 22(5):693-700. PubMed ID: 11323386
[TBL] [Abstract][Full Text] [Related]
9. Carcinogenicity in rats of a mutagenic compound, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole, from tryptophan pyrolysate.
Takayama S; Nakatsuru Y; Ohgaki H; Sato S; Sugimura T
Jpn J Cancer Res; 1985 Sep; 76(9):815-7. PubMed ID: 3932278
[TBL] [Abstract][Full Text] [Related]
10. 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) triggers apoptosis by DNA double-strand breaks caused by inhibition of topoisomerase I.
Shiotani B; Ashida H
Carcinogenesis; 2004 Jul; 25(7):1149-55. PubMed ID: 14976128
[TBL] [Abstract][Full Text] [Related]
11. 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces caspase-dependent apoptosis in mononuclear cells.
Hashimoto T; Ashida H; Sano T; Furuyashiki T; Hatanaka Y; Minato K; Mizuno M; Nomura K; Kumatori A; Kanazawa K; Danno G
Biochim Biophys Acta; 2001 May; 1539(1-2):44-57. PubMed ID: 11389967
[TBL] [Abstract][Full Text] [Related]
12. Apoptosis in the thymus after intraperitoneal injection of rats with Trp-P-1.
Hashimoto T; Furuyashiki T; Sano T; Kihara K; Fukuda I; Ito W; Park P; Kanazawa K; Danno G; Ashida H
Environ Mol Mutagen; 2002; 40(3):175-83. PubMed ID: 12355551
[TBL] [Abstract][Full Text] [Related]
13. Synergistic effects of food colors on the toxicity of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) in primary cultured rat hepatocytes.
Ashida H; Hashimoto T; Tsuji S; Kanazawa K; Danno G
J Nutr Sci Vitaminol (Tokyo); 2000 Jun; 46(3):130-6. PubMed ID: 10955279
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of tryptophan hydroxylase by food-derived carcinogenic heterocyclic amines, 3-amino-1-methyl-5H-pyrido[4,3-b]indole and 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole.
Naoi M; Hosoda S; Ota M; Takahashi T; Nagatsu T
Biochem Pharmacol; 1991 Jan; 41(2):199-203. PubMed ID: 1989631
[TBL] [Abstract][Full Text] [Related]
15. DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]-indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
Wakata A; Oka N; Hiramoto K; Yoshioka A; Negishi K; Wataya Y; Hayatsu H
Cancer Res; 1985 Nov; 45(11 Pt 2):5867-71. PubMed ID: 4053057
[TBL] [Abstract][Full Text] [Related]
16. Carcinogenic tryptophan pyrolysis products potent inhibitors of type A monoamine oxidase and the platelet response to 5-hydroxytryptamine.
Manabe S; Kanai Y; Ishikawa S; Wada O
J Clin Chem Clin Biochem; 1988 May; 26(5):265-70. PubMed ID: 3404091
[TBL] [Abstract][Full Text] [Related]
17. Chemical modification of DNA with muta-carcinogens. I. 3-Amino-1-methyl-5H-pyrido[4,3-b]indole and 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole: metabolic activation and structure of the DNA adducts.
Hashimoto Y; Shudo K
Environ Health Perspect; 1985 Oct; 62():209-14. PubMed ID: 4085425
[TBL] [Abstract][Full Text] [Related]
18. Ultrastructural and biochemical alterations induced by tryptophan pyrolysis products on rat hepatocytes in primary culture. I. Action on the transcriptional process.
Thybaud-Lambay V; Decloitre F; Moulé Y; Florentin Y
Carcinogenesis; 1983; 4(4):481-8. PubMed ID: 6839420
[TBL] [Abstract][Full Text] [Related]
19. Metabolic activation of mutagenic tryptophan pyrolysis products by rat liver microsomes.
Ishii K; Yamazoe Y; Kamataki T; Kato R
Cancer Res; 1980 Jul; 40(7):2596-600. PubMed ID: 6771001
[TBL] [Abstract][Full Text] [Related]
20. Carcinogenic activity of 3-amino-1-methyl-5H-pyrido [4,3-b]indole (Trp-P-2), a pyrolysis product of tryptophan.
Hosaka S; Matsushima T; Hirono I; Sugimura T
Cancer Lett; 1981 Jun; 13(1):23-8. PubMed ID: 7306941
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]