Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Astrocytoma AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207
1429 results:

  • 1. Multi-omics technologies and molecular biomarkers in brain tumor-related epilepsy.
    Du Y; Li R; Fu D; Zhang B; Cui A; Shao Y; Lai Z; Chen R; Chen B; Wang Z; Zhang W; Chu L
    CNS Neurosci Ther; 2024 Apr; 30(4):e14717. PubMed ID: 38641945
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Haploinsufficiency of phosphodiesterase 10A activates PI3K/akt signaling independent of PTEN to induce an aggressive glioma phenotype.
    Nuechterlein N; Shelbourn A; Szulzewsky F; Arora S; Casad M; Pattwell S; Merino-Galan L; Sulman E; Arowa S; Alvinez N; Jung M; Brown D; Tang K; Jackson S; Stoica S; Chittaboina P; Banasavadi-Siddegowda YK; Wirsching HG; Stella N; Shapiro L; Paddison P; Patel AP; Gilbert MR; Abdullaev Z; Aldape K; Pratt D; Holland EC; Cimino PJ
    Genes Dev; 2024 Apr; 38(5-6):273-288. PubMed ID: 38589034
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.
    Ji Q; Guo Y; Li Z; Zhang X
    Aging (Albany NY); 2024 Mar; 16(6):5601-5617. PubMed ID: 38535989
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. HNF1A induces glioblastoma by upregulating EPS8 and activating PI3K/akt signaling pathway.
    Yang G; Su F; Han BX; Su HX; Guo CH; Yu SH; Guan QL; Hou XM
    Biochem Pharmacol; 2024 May; 223():116133. PubMed ID: 38494066
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Discrete Mechanistic Target of Rapamycin Signaling Pathways, Stem Cells, and Therapeutic Targets.
    Jhanwar-Uniyal M; Zeller SL; Spirollari E; Das M; Hanft SJ; Gandhi CD
    Cells; 2024 Feb; 13(5):. PubMed ID: 38474373
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Glioblastoma Therapy: Past, Present and Future.
    Obrador E; Moreno-Murciano P; Oriol-Caballo M; López-Blanch R; Pineda B; Gutiérrez-Arroyo JL; Loras A; Gonzalez-Bonet LG; Martinez-Cadenas C; Estrela JM; Marqués-Torrejón MÁ
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473776
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Zeaxanthin impairs angiogenesis and tumor growth of glioblastoma: An in vitro and in vivo study.
    Lu F; Wu Q; Lei J; Zhou Y; Liu Y; Zhu N; Yu Y; Lin L; Hu M
    Arch Biochem Biophys; 2024 Apr; 754():109957. PubMed ID: 38467357
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. CD133 significance in glioblastoma development: in silico and in vitro study.
    Abdoli Shadbad M; Nejadi Orang F; Baradaran B
    Eur J Med Res; 2024 Mar; 29(1):154. PubMed ID: 38448914
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Metabolic remodeling by the PD-L1 inhibitor BMS-202 significantly inhibits cell malignancy in human glioblastoma.
    Yang X; Wang W; Ji T
    Cell Death Dis; 2024 Mar; 15(3):186. PubMed ID: 38438374
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives.
    Fernandes S; Vieira M; Prudêncio C; Ferraz R
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396785
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Modulation of Apoptotic and akt/PI3K/mTOR pathways to target Glioblastoma Cells using synthetic compound PGEA-AN.
    Saad S; Hanif F; Simjee SU; Faizi S; Khan L; Ashfaque A
    J Pak Med Assoc; 2024 Feb; 74(1 (Supple-2)):S39-S46. PubMed ID: 38385470
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Antiproliferative effect of Potentilla fulgens on glioblastoma cancer cells through downregulation of akt/mTOR signaling pathway.
    Kandemir SI; Ipek P
    J Cancer Res Ther; 2023 Oct; 19(7):1818-1824. PubMed ID: 38376284
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands.
    Macdonald-Obermann JL; Pike LJ
    J Biol Chem; 2024 Mar; 300(3):105763. PubMed ID: 38367671
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments.
    Ge W; Yuan G; Wang D; Dong L
    Sci Rep; 2024 Feb; 14(1):3783. PubMed ID: 38360888
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Exploration of functional relations among differentially co-expressed genes identifies regulators in glioblastoma.
    Kumar S; Sarmah DT; Paul A; Chatterjee S
    Comput Biol Chem; 2024 Apr; 109():108024. PubMed ID: 38335855
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/akt/mTOR signaling pathway.
    Dong J; Qian Y; Zhang W; Xu J; Wang L; Fan Z; Jia M; Wei L; Yang H; Luo X; Wang Y; Jiang Y; Huang Z; Wang Y
    Eur J Pharmacol; 2024 Apr; 968():176401. PubMed ID: 38331340
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating akt1 signaling.
    Wang B; Zhang X; Li ZS; Wei C; Yu RZ; Du XZ; He YJ; Ren Y; Zhen YW; Han L
    Cancer Lett; 2024 Mar; 585():216665. PubMed ID: 38290657
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Simulated microgravity induces DNA damage concurrent with impairment of DNA repair and activation of cell-type specific DNA damage response in microglial and glioblastoma cells.
    Singh R; Jaiswal A; Singh RP
    Biochim Biophys Acta Mol Cell Res; 2024 Mar; 1871(3):119679. PubMed ID: 38272357
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Unraveling the impact of miR-21 on apoptosis regulation in glioblastoma.
    Shaikh MAJ; Altamimi ASA; Afzal M; Gupta G; Singla N; Gilhotra R; Almalki WH; Kazmi I; Alzarea SI; Prasher P; Singh SK; Dua K
    Pathol Res Pract; 2024 Feb; 254():155121. PubMed ID: 38262269
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Role of Luteolin as Potential New Therapeutic Option for Patients with Glioblastoma through Regulation of Sphingolipid Rheostat.
    Navone SE; Guarnaccia L; Rizzaro MD; Begani L; Barilla E; Alotta G; Garzia E; Caroli M; Ampollini A; Violetti A; Gervasi N; Campanella R; Riboni L; Locatelli M; Marfia G
    Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203299
    [TBL] [Abstract] [Full Text] [Related]  


    of 72.