BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Astrocytoma AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
16 results:

  • 1. Molecular and clinicopathological implications of PRAME expression in adult glioma.
    Le MK; Vuong HG; Dunn IF; Kondo T
    PLoS One; 2023; 18(10):e0290542. PubMed ID: 37796789
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer.
    Urbaniak A; Reed MR; Heflin B; Gaydos J; Piña-Oviedo S; Jędrzejczyk M; Klejborowska G; Stępczyńska N; Chambers TC; Tackett AJ; Rodriguez A; Huczyński A; Eoff RL; MacNicol AM
    Biomed Pharmacother; 2022 Sep; 153():113440. PubMed ID: 36076555
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A Radiosensitivity Gene Signature and PD-L1 Status Predict clinical outcome of Patients with Glioblastoma Multiforme in The Cancer Genome Atlas Dataset.
    Jang BS; Kim IA
    Cancer Res Treat; 2020 Apr; 52(2):530-542. PubMed ID: 31801317
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-akt1 Complex Modulates Glioblastoma Therapy Sensitivity.
    Vehlow A; Klapproth E; Jin S; Hannen R; Hauswald M; Bartsch JW; Nimsky C; Temme A; Leitinger B; Cordes N
    Cell Rep; 2019 Mar; 26(13):3672-3683.e7. PubMed ID: 30917320
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. akt/GSK3β Signaling in Glioblastoma.
    Majewska E; Szeliga M
    Neurochem Res; 2017 Mar; 42(3):918-924. PubMed ID: 27568206
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway.
    Dhruv HD; Roos A; Tomboc PJ; Tuncali S; Chavez A; Mathews I; Berens ME; Loftus JC; Tran NL
    J Neurooncol; 2016 Feb; 126(3):397-404. PubMed ID: 26559543
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma.
    Wachsberger PR; Lawrence YR; Liu Y; Rice B; Feo N; Leiby B; Dicker AP
    J Cancer Res Clin Oncol; 2014 Apr; 140(4):573-82. PubMed ID: 24500492
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. TRIM24 promotes glioma progression and enhances chemoresistance through activation of the PI3K/akt signaling pathway.
    Zhang LH; Yin AA; Cheng JX; Huang HY; Li XM; Zhang YQ; Han N; Zhang X
    Oncogene; 2015 Jan; 34(5):600-10. PubMed ID: 24469053
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Molecular interactions of ErbB1 (EGFR) and integrin-β1 in astrocytoma frozen sections predict clinical outcome and correlate with akt-mediated in vitro radioresistance.
    Petrás M; Lajtos T; Friedländer E; Klekner A; Pintye E; Feuerstein BG; Szöllosi J; Vereb G
    Neuro Oncol; 2013 Aug; 15(8):1027-40. PubMed ID: 23595626
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Inhibition of STAT3 reverses alkylator resistance through modulation of the akt and β-catenin signaling pathways.
    Wang Y; Chen L; Bao Z; Li S; You G; Yan W; Shi Z; Liu Y; Yang P; Zhang W; Han L; Kang C; Jiang T
    Oncol Rep; 2011 Nov; 26(5):1173-80. PubMed ID: 21887474
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on akt2 function.
    Fortin SP; Ennis MJ; Savitch BA; Carpentieri D; McDonough WS; Winkles JA; Loftus JC; Kingsley C; Hostetter G; Tran NL
    Mol Cancer Res; 2009 Nov; 7(11):1871-81. PubMed ID: 19861406
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Molecular profiling in glioblastoma: prelude to personalized treatment.
    Mladkova N; Chakravarti A
    Curr Oncol Rep; 2009 Jan; 11(1):53-61. PubMed ID: 19080742
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Identification of survival-related genes of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma multiforme.
    Ruano Y; Mollejo M; Camacho FI; Rodríguez de Lope A; Fiaño C; Ribalta T; Martínez P; Hernández-Moneo JL; Meléndez B
    Cancer; 2008 Apr; 112(7):1575-84. PubMed ID: 18260157
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Prognostic factors for anaplastic astrocytomas.
    Compostella A; Tosoni A; Blatt V; Franceschi E; Brandes AA
    J Neurooncol; 2007 Feb; 81(3):295-303. PubMed ID: 17001519
    [TBL] [Abstract] [Full Text] [Related]  


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