BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND HEY1, CHF-2, 23462, ENSG00000164683, HESR1, CHF2, HESR-1, MGC1274, HRT-1, OAF1, HERP2
40 results:

  • 1. Small cell osteosarcoma versus fusion-driven round cell sarcomas of bone: retrospective clinical, radiological, pathological, and (epi)genetic comparison with clinical implications.
    Hiemcke-Jiwa LS; Sumathi VP; Baumhoer D; Smetsers SE; Haveman LM; van Noesel MM; van Langevelde K; Cleven AHG; van de Sande MAJ; Ter Horst SAJ; Kester LA; Flucke U
    Virchows Arch; 2024 Mar; 484(3):451-463. PubMed ID: 38332052
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
    Liang G; Duan C; He J; Shi L
    Toxicol Appl Pharmacol; 2024 Feb; 483():116826. PubMed ID: 38228236
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Knocking down SOX2 overcomes the resistance of prostate cancer to castration via notch signaling.
    Du Z; Chen X; Zhu P; Lv Q; Yong J; Gu J
    Mol Biol Rep; 2023 Nov; 50(11):9007-9017. PubMed ID: 37716921
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Detection of mesenchymal chondrosarcoma in pleural effusion with immunocytochemistry and determination of hey1::NCOA2 fusion by next-generation sequencing on cell block.
    Zhong J; Wang Q; Xie Y; Niu Z; Zhou D
    Cytopathology; 2024 Jan; 35(1):149-152. PubMed ID: 37688410
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. NKX3.1 immunohistochemistry and methylome profiling in mesenchymal chondrosarcoma: additional diagnostic value for a well-defined disease?
    Glauser S; Ameline B; Andrei V; Harder D; Pauli C; Trautmann M; Hartmann W; Baumhoer D
    Pathology; 2023 Aug; 55(5):621-628. PubMed ID: 37225644
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Novel low-grade renal spindle cell neoplasm with hey1::NCOA2 fusion that is distinct from mesenchymal chondrosarcoma.
    Miller TI; Mantilla JG; Wang W; Liu YJ; Tretiakova M
    Genes Chromosomes Cancer; 2023 Mar; 62(3):171-175. PubMed ID: 36416671
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Construction of a transcription factor-miRNA-mRNA interactive network elucidates underlying pathogenesis for osteosarcoma and validation by qRT-PCR.
    Tang F; Jiang X; Liao S; Liu Y; He M
    Medicine (Baltimore); 2022 Oct; 101(41):e31049. PubMed ID: 36254052
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genomic profiling identifies genes and pathways dysregulated by hey1-NCOA2 fusion and shines a light on mesenchymal chondrosarcoma tumorigenesis.
    Qi W; Rosikiewicz W; Yin Z; Xu B; Jiang H; Wan S; Fan Y; Wu G; Wang L
    J Pathol; 2022 Aug; 257(5):579-592. PubMed ID: 35342947
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Patient-derived xenografts and in vitro model show rationale for imatinib mesylate repurposing in hey1-NCoA2-driven mesenchymal chondrosarcoma.
    Safaric Tepes P; Segovia D; Jevtic S; Ramirez D; Lyons SK; Sordella R
    Lab Invest; 2022 Sep; 102(9):1038-1049. PubMed ID: 34837064
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Malignant Cartilage-Forming Tumors.
    Hameed M
    Surg Pathol Clin; 2021 Dec; 14(4):605-617. PubMed ID: 34742483
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. NKX3.1 immunohistochemistry is highly specific for the diagnosis of mesenchymal chondrosarcomas: experience in the Australian population.
    Ramanayake N; Vargas AC; Talbot J; Bonar F; Wong DD; Wong D; Mahar A; Karim R; Luk PP; Selinger C; Sioson L; Gill AJ; Maclean F
    Pathology; 2021 Oct; 53(6):705-712. PubMed ID: 33640159
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Causal Bayesian gene networks associated with bone, brain and lung metastasis of breast cancer.
    Park SB; Hwang KT; Chung CK; Roy D; Yoo C
    Clin Exp Metastasis; 2020 Dec; 37(6):657-674. PubMed ID: 33083937
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. JAGGED1 stimulates cranial neural crest cell osteoblast commitment pathways and bone regeneration independent of canonical NOTCH signaling.
    Kamalakar A; McKinney JM; Salinas Duron D; Amanso AM; Ballestas SA; Drissi H; Willett NJ; Bhattaram P; García AJ; Wood LB; Goudy SL
    Bone; 2021 Feb; 143():115657. PubMed ID: 32980561
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. NKX3.1 immunoreactivity is not identified in mesenchymal chondrosarcoma: a 25-case cohort study.
    Chen W; Hornick JL; Fletcher CDM
    Histopathology; 2021 Jan; 78(2):334-337. PubMed ID: 32779239
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. [Cartilage tumors: morphology, genetics, and current aspects of target therapy].
    Roessner A; Smolle M; Schoeder V; Haybaeck J
    Pathologe; 2020 Mar; 41(2):143-152. PubMed ID: 32060685
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. An update of molecular pathology of bone tumors. Lessons learned from investigating samples by next generation sequencing.
    Baumhoer D; Amary F; Flanagan AM
    Genes Chromosomes Cancer; 2019 Feb; 58(2):88-99. PubMed ID: 30582658
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Minute mesenchymal chondrosarcoma within osteochondroma: an unexpected diagnosis confirmed by hey1-NCOA2 fusion.
    Toki S; Motoi T; Miyake M; Kobayashi E; Kawai A; Yoshida A
    Hum Pathol; 2018 Nov; 81():255-260. PubMed ID: 29596896
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology.
    El Beaino M; Roszik J; Livingston JA; Wang WL; Lazar AJ; Amini B; Subbiah V; Lewis V; Conley AP
    Curr Oncol Rep; 2018 Mar; 20(5):37. PubMed ID: 29582189
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. 18F-FDG PET/CT Findings of Mesenchymal Chondrosarcoma of the Orbit.
    Tsuchiya M; Masui T; Otsuki Y; Sakahara H
    Clin Nucl Med; 2018 Feb; 43(2):e43-e45. PubMed ID: 29215408
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Integrating Morphology and Genetics in the Diagnosis of Cartilage Tumors.
    de Andrea CE; San-Julian M; Bovée JVMG
    Surg Pathol Clin; 2017 Sep; 10(3):537-552. PubMed ID: 28797501
    [TBL] [Abstract] [Full Text] [Related]  


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