Terms: = Bone cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
70 results:
1. Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma.
Wei L; Meng J; Xiang D; Yang Q; Zhou Y; Xu L; Wang M; Chen J; Han Y
BMC Complement Med Ther; 2024 Jan; 24(1):67. PubMed ID: 38297292
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2. Exploration of anti‑osteosarcoma activity of asiatic acid based on network pharmacology and
Pang H; Wu H; Zhan Z; Wu T; Xiang M; Wang Z; Song L; Wei B
Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38186298
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3. A newly identified 45-kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance.
Gorantla SP; Mueller TA; Albers-Leischner C; Rudelius M; von Bubnoff N; Duyster J
Mol Oncol; 2024 Feb; 18(2):415-430. PubMed ID: 38104968
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4. The anti-oncogenic effect of 17-DMAG via the inactivation of hsp90 and MET pathway in osteosarcoma cells.
Kawano M; Tanaka K; Itonaga I; Iwasaki T; Kubota Y; Tsumura H
Oncol Res; 2023; 31(5):631-643. PubMed ID: 37547755
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5. Identification and validation of a novel overall survival prediction model for immune-related genes in bone metastases of prostate cancer.
Bi W; Guo W; Fan G; Xie L; Jiang C
Aging (Albany NY); 2023 Jul; 15(14):7161-7186. PubMed ID: 37494663
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6. Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel hsp90 C-terminal domain inhibitors against Ewing sarcoma.
Zajec Ž; Dernovšek J; Distel M; Gobec M; Tomašič T
Bioorg Chem; 2023 Feb; 131():106311. PubMed ID: 36495678
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7. Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2.
Chen X; Yang P; Qiao Y; Ye F; Wang Z; Xu M; Han X; Song L; Wu Y; Ou WB
Sci Rep; 2022 Nov; 12(1):18830. PubMed ID: 36335201
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8. FOXO3a-dependent up-regulation of hsp90 alleviates cisplatin-induced apoptosis by activating FUNDC1-mediated mitophagy in hypoxic osteosarcoma cells.
Lu D; Liu R; Zhou Y; Zhang Z; Jiang X; Xu J; Su A; Hu Z
Cell Signal; 2023 Jan; 101():110500. PubMed ID: 36270475
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9. Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Wang S; Wang T; Yang Q; Cheng S; Liu F; Yang G; Wang F; Wang R; Yang D; Zhou M; Duan C; Zhang Y; Liu H; Dai Z; Tian K; Liu S
Cell Oncol (Dordr); 2022 Oct; 45(5):951-965. PubMed ID: 36129611
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10. Canine osteosarcoma cells exhibit basal accumulation of multiple chaperone proteins and are sensitive to small molecule inhibitors of GRP78 and heat shock protein function.
Mattos DR; Weinman MA; Wan X; Goodall CP; Serrill JD; McPhail KL; Milovancev M; Bracha S; Ishmael JE
Cell Stress Chaperones; 2022 May; 27(3):223-239. PubMed ID: 35244890
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11. Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia.
Bruserud Ø; Reikvam H; Brenner AK
Molecules; 2022 Jan; 27(3):. PubMed ID: 35163998
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12. Advances in the role of heat shock protein 90 in prostate cancer.
Fu Z; Jia B
Andrologia; 2022 May; 54(4):e14376. PubMed ID: 35075667
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13. Suppression of breast cancer-associated bone loss with osteoblast proteomes via hsp90ab1/moesin-mediated inhibition of TGFβ/FN1/CD44 signaling.
Sun X; Li K; Hase M; Zha R; Feng Y; Li BY; Yokota H
Theranostics; 2022; 12(2):929-943. PubMed ID: 34976221
[No Abstract] [Full Text] [Related]
14. hsp90 regulates the tumorigenic function of tyrosine protein kinase in osteosarcoma.
Yao ZP; Zhu H; Shen F; Gong D
Clin Exp Pharmacol Physiol; 2022 Mar; 49(3):380-390. PubMed ID: 34767669
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15. Impact of hsp90
Zhou W; Yang Y; Wang Z; Liu Y; Lari Najafi M
J Healthc Eng; 2021; 2021():6929971. PubMed ID: 34721827
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16. Pharmacological Inhibition of hsp90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Naz S; Leiker AJ; Choudhuri R; Preston O; Sowers AL; Gohain S; Gamson J; Mathias A; Van Waes C; Cook JA; Mitchell JB
Int J Radiat Oncol Biol Phys; 2021 Aug; 110(5):1295-1305. PubMed ID: 33838214
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17. Investigation of anticancer activities of STA-9090 (ganetespib) as a second generation hsp90 inhibitor in Saos-2 osteosarcoma cells.
Özgür A
J Chemother; 2021 Dec; 33(8):554-563. PubMed ID: 33794753
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18. Mild microwave ablation combined with hsp90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma.
Chen L; Wang M; Lin Z; Yao M; Wang W; Cheng S; Li B; Zhang Y; Yin Q
Mol Med Rep; 2020 Aug; 22(2):906-914. PubMed ID: 32468060
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19. hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway.
Shu X; Liu H; Zhen R; Jie Y; Chen L; Qi H; Wang C; Wang R; Chen D; Ran Y
Oncol Rep; 2020 Jul; 44(1):313-324. PubMed ID: 32377704
[TBL] [Abstract] [Full Text] [Related]
20. The Major Heat Shock Proteins, Hsp70 and hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model.
Gorska-Ponikowska M; Kuban-Jankowska A; Marino Gammazza A; Daca A; Wierzbicka JM; Zmijewski MA; Luu HH; Wozniak M; Cappello F
Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31963524
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