BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND JAK3, L-JAK, 3718, ENSG00000105639, P52333, JAKL, JAK-3, LJAK, JAK3_HUMAN AND Treatment
14 results:

  • 1. First Approval of Pacritinib as a Selective Janus Associated Kinase-2 Inhibitor for the treatment of Patients with Myelofibrosis.
    De SK
    Anticancer Agents Med Chem; 2023; 23(12):1355-1360. PubMed ID: 36959157
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions.
    Dvorak CC; Haddad E; Heimall J; Dunn E; Cowan MJ; Pai SY; Kapoor N; Satter LF; Buckley RH; O'Reilly RJ; Chandra S; Bednarski JJ; Williams O; Rayes A; Moore TB; Ebens CL; Davila Saldana BJ; Petrovic A; Chellapandian D; Cuvelier GDE; Vander Lugt MT; Caywood EH; Chandrakasan S; Eissa H; Goldman FD; Shereck E; Aquino VM; Desantes KB; Madden LM; Miller HK; Yu L; Broglie L; Gillio A; Shah AJ; Knutsen AP; Andolina JP; Joshi AY; Szabolcs P; Kapadia M; Martinez CA; Parrot RE; Sullivan KE; Prockop SE; Abraham RS; Thakar MS; Leiding JW; Kohn DB; Pulsipher MA; Griffith LM; Notarangelo LD; Puck JM
    J Allergy Clin Immunol; 2023 Feb; 151(2):547-555.e5. PubMed ID: 36456360
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Suppressive function of bone marrow-derived mesenchymal stem cell-derived exosomal microRNA-187 in prostate cancer.
    Li C; Sun Z; Song Y; Zhang Y
    Cancer Biol Ther; 2022 Dec; 23(1):1-14. PubMed ID: 36245088
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. IL-7: Comprehensive review.
    Winer H; Rodrigues GOL; Hixon JA; Aiello FB; Hsu TC; Wachter BT; Li W; Durum SK
    Cytokine; 2022 Dec; 160():156049. PubMed ID: 36201890
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells' Migration and Invasion in Culture by Inhibition of uPA via the JAK/STAT Signaling Pathway.
    Lu KH; Wu HH; Lin RC; Lin YC; Lu PW; Yang SF; Yang JS
    Molecules; 2020 Dec; 26(1):. PubMed ID: 33374783
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.
    Haddad E; Logan BR; Griffith LM; Buckley RH; Parrott RE; Prockop SE; Small TN; Chaisson J; Dvorak CC; Murnane M; Kapoor N; Abdel-Azim H; Hanson IC; Martinez C; Bleesing JJH; Chandra S; Smith AR; Cavanaugh ME; Jyonouchi S; Sullivan KE; Burroughs L; Skoda-Smith S; Haight AE; Tumlin AG; Quigg TC; Taylor C; Dávila Saldaña BJ; Keller MD; Seroogy CM; Desantes KB; Petrovic A; Leiding JW; Shyr DC; Decaluwe H; Teira P; Gillio AP; Knutsen AP; Moore TB; Kletzel M; Craddock JA; Aquino V; Davis JH; Yu LC; Cuvelier GDE; Bednarski JJ; Goldman FD; Kang EM; Shereck E; Porteus MH; Connelly JA; Fleisher TA; Malech HL; Shearer WT; Szabolcs P; Thakar MS; Vander Lugt MT; Heimall J; Yin Z; Pulsipher MA; Pai SY; Kohn DB; Puck JM; Cowan MJ; O'Reilly RJ; Notarangelo LD
    Blood; 2018 Oct; 132(17):1737-1749. PubMed ID: 30154114
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Chronic lymphoproliferative disorder of NK-cells: A single-institution review with emphasis on relative utility of multimodality diagnostic tools.
    Kurt H; Jorgensen JL; Amin HM; Patel KP; Wang SA; Lin P; Kanagal-Shamanna R; Loghavi S; Thakral B; Khogeer HA; Jabbour EJ; Li S; Yin CC; Medeiros LJ; Khoury JD
    Eur J Haematol; 2018 May; 100(5):444-454. PubMed ID: 29385279
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Novel jak3-Activating Mutations in Extranodal NK/T-Cell Lymphoma, Nasal Type.
    Sim SH; Kim S; Kim TM; Jeon YK; Nam SJ; Ahn YO; Keam B; Park HH; Kim DW; Kim CW; Heo DS
    Am J Pathol; 2017 May; 187(5):980-986. PubMed ID: 28284718
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. IL-4 enhances expression and function of surface IgM in CLL cells.
    Aguilar-Hernandez MM; Blunt MD; Dobson R; Yeomans A; Thirdborough S; Larrayoz M; Smith LD; Linley A; Strefford JC; Davies A; Johnson PM; Savelyeva N; Cragg MS; Forconi F; Packham G; Stevenson FK; Steele AJ
    Blood; 2016 Jun; 127(24):3015-25. PubMed ID: 27002119
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. JAK Inhibition Impairs NK Cell Function in Myeloproliferative Neoplasms.
    Schönberg K; Rudolph J; Vonnahme M; Parampalli Yajnanarayana S; Cornez I; Hejazi M; Manser AR; Uhrberg M; Verbeek W; Koschmieder S; Brümmendorf TH; Brossart P; Heine A; Wolf D
    Cancer Res; 2015 Jun; 75(11):2187-99. PubMed ID: 25832652
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.
    De Mattos-Arruda L; Weigelt B; Cortes J; Won HH; Ng CKY; Nuciforo P; Bidard FC; Aura C; Saura C; Peg V; Piscuoglio S; Oliveira M; Smolders Y; Patel P; Norton L; Tabernero J; Berger MF; Seoane J; Reis-Filho JS
    Ann Oncol; 2014 Sep; 25(9):1729-1735. PubMed ID: 25009010
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Detection of an activated jak3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis.
    Kunze K; Gamerdinger U; Leßig-Owlanj J; Sorokina M; Brobeil A; Tur MK; Blau W; Burchardt A; Käbisch A; Schliesser G; Kiehl M; Rosenwald A; Rummel M; Grimminger F; Hain T; Chakraborty T; Bräuninger A; Gattenlöhner S
    Pathol Res Pract; 2014 Jun; 210(6):369-76. PubMed ID: 24674452
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The jak3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
    Steele AJ; Prentice AG; Cwynarski K; Hoffbrand AV; Hart SM; Lowdell MW; Samuel ER; Wickremasinghe RG
    Blood; 2010 Nov; 116(22):4569-77. PubMed ID: 20716767
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.
    Haque SJ; Harbor P; Tabrizi M; Yi T; Williams BR
    J Biol Chem; 1998 Dec; 273(51):33893-6. PubMed ID: 9852037
    [TBL] [Abstract] [Full Text] [Related]  


    of 1.