BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
18 results:

  • 1. A tumor suppressor protein encoded by circkeap1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.
    Zhang Y; Liu Z; Zhong Z; Ji Y; Guo H; Wang W; Chen C
    J Exp Clin Cancer Res; 2024 Feb; 43(1):52. PubMed ID: 38383479
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors.
    Wang X; Su S; Zhu Y; Cheng X; Cheng C; Chen L; Lei A; Zhang L; Xu Y; Ye D; Zhang Y; Li W; Zhang J
    Nat Commun; 2023 Sep; 14(1):5778. PubMed ID: 37723178
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Comparative bioinformatic analysis of KRAS, STK11 and keap1 (co-)mutations in non-small cell lung cancer with a special focus on KRAS G12C.
    Boeschen M; Kuhn CK; Wirtz H; Seyfarth HJ; Frille A; Lordick F; Hacker UT; Obeck U; Stiller M; Bläker H; von Laffert M
    Lung Cancer; 2023 Oct; 184():107361. PubMed ID: 37699269
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Molecular markers of metastatic disease in KRAS-mutant lung adenocarcinoma.
    Boiarsky D; Lydon CA; Chambers ES; Sholl LM; Nishino M; Skoulidis F; Heymach JV; Luo J; Awad MA; Janne PA; Van Allen EM; Barbie DA; Vokes NI
    Ann Oncol; 2023 Jul; 34(7):589-604. PubMed ID: 37121400
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling.
    Liu W; Zhao Y; Wang G; Feng S; Ge X; Ye W; Wang Z; Zhu Y; Cai W; Bai J; Zhou X
    Redox Biol; 2022 Jul; 53():102344. PubMed ID: 35636015
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells.
    Simon-Molas H; Sánchez-de-Diego C; Navarro-Sabaté À; Castaño E; Ventura F; Bartrons R; Manzano A
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163828
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma.
    Chen L; Jin XH; Luo J; Duan JL; Cai MY; Chen JW; Feng ZH; Guo AM; Wang FW; Xie D
    Oncogene; 2021 Oct; 40(40):5925-5937. PubMed ID: 34363021
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The Multifaceted Roles of USP15 in Signal Transduction.
    Das T; Song EJ; Kim EE
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946990
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Sinomenine protects bone from destruction to ameliorate arthritis via activating p62
    Liao K; Su X; Lei K; Liu Z; Lu L; Wu Q; Pan H; Huang Q; Zhao Y; Wang M; Cai J; Liu L; Li T
    Biomed Pharmacother; 2021 Mar; 135():111195. PubMed ID: 33395605
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Recognition of the organ-specific mutations in metastatic breast cancer by circulating tumor cells isolated in vivo.
    Li S; Yang S; Shi J; Ding Y; Gao W; Cheng M; Sun Y; Xie Y; Sang M; Yang H; Geng C
    Neoplasma; 2021 Jan; 68(1):31-39. PubMed ID: 32940042
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
    Yu YP; Cai LC; Wang XY; Cheng SY; Zhang DM; Jian WG; Wang TD; Yang JK; Yang KB; Zhang C
    Cancer Sci; 2020 May; 111(5):1555-1566. PubMed ID: 32128917
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of cancers.
    Soundararajan P; Kim JS
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30445746
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. p62/SQSTM1 - steering the cell through health and disease.
    Sánchez-Martín P; Komatsu M
    J Cell Sci; 2018 Nov; 131(21):. PubMed ID: 30397181
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genetic and clonal dissection of osteosarcoma progression and lung metastasis.
    Xu H; Zhu X; Bao H; Wh Shek T; Huang Z; Wang Y; Wu X; Wu Y; Chang Z; Wu S; Tang Q; Zhang H; Han A; Mc Cheung K; Zou C; Yau R; Ho WY; Huang G; Batalha S; Lu J; Song G; Kang Y; Shao YW; Lam YL; Shen J; Wang J
    Int J Cancer; 2018 Sep; 143(5):1134-1142. PubMed ID: 29569716
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells.
    Rodrigues-Moreira S; Moreno SG; Ghinatti G; Lewandowski D; Hoffschir F; Ferri F; Gallouet AS; Gay D; Motohashi H; Yamamoto M; Joiner MC; Gault N; Romeo PH
    Cell Rep; 2017 Sep; 20(13):3199-3211. PubMed ID: 28954235
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Expression of the Nrf2 and keap1 proteins and their clinical significance in osteosarcoma.
    Zhang J; Wang X; Wu W; Dang H; Wang B
    Biochem Biophys Res Commun; 2016 Apr; 473(1):42-46. PubMed ID: 26987716
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Role of growth hormone in maturation and activation of dendritic cells via miR-200a and the keap1/Nrf2 pathway.
    Liu QL; Zhang J; Liu X; Gao JY
    Cell Prolif; 2015 Oct; 48(5):573-81. PubMed ID: 26289744
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Basic principles and emerging concepts in the redox control of transcription factors.
    Brigelius-Flohé R; Flohé L
    Antioxid Redox Signal; 2011 Oct; 15(8):2335-81. PubMed ID: 21194351
    [TBL] [Abstract] [Full Text] [Related]  


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