Terms: = Bone cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
82 results:
1. ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway.
Zheng D; Wei Z; Zhang C; Liu W; Gong C; Wu F; Guo W
Biol Direct; 2024 Apr; 19(1):28. PubMed ID: 38650011
[TBL] [Abstract] [Full Text] [Related]
2. Bruceine A: Suppressing metastasis via MEK/ERK pathway and invoking mitochondrial apoptosis in triple-negative breast cancer.
Li X; Liu C; Zhang X; Sun C; Ling J; Liu Y; Zuo Y; Cao Y; Zhang C; Jiang T; Wang M; Liu J; Lu J
Biomed Pharmacother; 2023 Dec; 168():115784. PubMed ID: 37879215
[TBL] [Abstract] [Full Text] [Related]
3. Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models.
Dyshlovoy SA; Hauschild J; Venz S; Krisp C; Kolbe K; Zapf S; Heinemann S; Fita KD; Shubina LK; Makarieva TN; Guzii AG; Rohlfing T; Kaune M; Busenbender T; Mair T; Moritz M; Poverennaya EV; Schlüter H; Serdyuk V; Stonik VA; Dierlamm J; Bokemeyer C; Mohme M; Westphal M; Lamszus K; von Amsberg G; Maire CL
Mol Pharm; 2023 Oct; 20(10):4994-5005. PubMed ID: 37733943
[TBL] [Abstract] [Full Text] [Related]
4. TRIM26 inhibited osteosarcoma progression through destabilizing RACK1 and thus inactivation of MEK/ERK signaling.
Xia K; Zheng D; Wei Z; Liu W; Guo W
Cell Death Dis; 2023 Aug; 14(8):529. PubMed ID: 37591850
[TBL] [Abstract] [Full Text] [Related]
5. Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma.
Ren Z; Xiao W; He M; Bai L
Chem Biol Interact; 2023 Mar; 373():110354. PubMed ID: 36706893
[TBL] [Abstract] [Full Text] [Related]
6. Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study.
Kemps PG; Zondag TCE; Arnardóttir HB; Solleveld-Westerink N; Borst J; Steenwijk EC; van Egmond D; Swennenhuis JF; Stelloo E; Trambusti I; Verdijk RM; van Noesel CJM; Cleven AHG; Scheijde-Vermeulen MA; Koudijs MJ; Krsková L; Hawkins C; Egeler RM; Brok J; von Bahr Greenwood T; Svojgr K; Beishuizen A; van Laar JAM; Pötschger U; Hutter C; Sieni E; Minkov M; Abla O; van Wezel T; van den Bos C; van Halteren AGS
Blood Adv; 2023 Feb; 7(4):664-679. PubMed ID: 36083130
[TBL] [Abstract] [Full Text] [Related]
7. Clinical study of map2k1-mutated Langerhans cell histiocytosis in children.
Yang Y; Wang C; Wang D; Cui L; Li N; Lian H; Ma H; Zhao Y; Zhang L; Liu W; Wang Y; Wu W; Zhang R; Li Z; Wang T
J Cancer Res Clin Oncol; 2022 Sep; 148(9):2517-2527. PubMed ID: 34595543
[TBL] [Abstract] [Full Text] [Related]
8. A Pedigree Analysis and Clonal Correlations of the Coexistence of B-Cell Lymphoma and Histiocytic/Dendritic Cell Tumor.
Cheng F; Yu F; Wang X; Huang K; Lu H; Wang Z
Int J Surg Pathol; 2021 Dec; 29(8):906-914. PubMed ID: 33939500
[TBL] [Abstract] [Full Text] [Related]
9. Dual inhibition of mek1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
Hoang VT; Matossian MD; La J; Hoang K; Ucar DA; Elliott S; Burks HE; Wright TD; Patel S; Bhatt A; Phamduy T; Chrisey D; Buechlein A; Rusch DB; Nephew KP; Anbalagan M; Rowan B; Cavanaugh JE; Flaherty PT; Miele L; Collins-Burow BM; Burow ME
J Cell Biochem; 2021 Aug; 122(8):835-850. PubMed ID: 33876843
[TBL] [Abstract] [Full Text] [Related]
10. bone Morphogenic Protein Signaling and Melanoma.
Kraj P
Curr Treat Options Oncol; 2021 Apr; 22(6):48. PubMed ID: 33866453
[TBL] [Abstract] [Full Text] [Related]
11. Signaling pathways in human osteoclasts differentiation: ERK1/2 as a key player.
Pennanen P; Kallionpää RA; Peltonen S; Nissinen L; Kähäri VM; Heervä E; Peltonen J
Mol Biol Rep; 2021 Feb; 48(2):1243-1254. PubMed ID: 33486672
[TBL] [Abstract] [Full Text] [Related]
12. Tomatidine Alleviates Osteoporosis by Downregulation of p53.
Yu T; Wu Q; You X; Zhou H; Xu S; He W; Li Z; Li B; Xia J; Zhu H; Zhao Y; Yang Y; Chen K
Med Sci Monit; 2020 Apr; 26():e923996. PubMed ID: 32300098
[TBL] [Abstract] [Full Text] [Related]
13. Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia.
Laurent AP; Siret A; Ignacimouttou C; Panchal K; Diop M; Jenni S; Tsai YC; Roos-Weil D; Aid Z; Prade N; Lagarde S; Plassard D; Pierron G; Daudigeos E; Lecluse Y; Droin N; Bornhauser BC; Cheung LC; Crispino JD; Gaudry M; Bernard OA; Macintyre E; Barin Bonnigal C; Kotecha RS; Geoerger B; Ballerini P; Bourquin JP; Delabesse E; Mercher T; Malinge S
Clin Cancer Res; 2020 Jul; 26(13):3307-3318. PubMed ID: 32220889
[TBL] [Abstract] [Full Text] [Related]
14. Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Fortin J; Tian R; Zarrabi I; Hill G; Williams E; Sanchez-Duffhues G; Thorikay M; Ramachandran P; Siddaway R; Wong JF; Wu A; Apuzzo LN; Haight J; You-Ten A; Snow BE; Wakeham A; Goldhamer DJ; Schramek D; Bullock AN; Dijke PT; Hawkins C; Mak TW
Cancer Cell; 2020 Mar; 37(3):308-323.e12. PubMed ID: 32142668
[TBL] [Abstract] [Full Text] [Related]
15. Erdheim-Chester disease.
Haroche J; Cohen-Aubart F; Amoura Z
Blood; 2020 Apr; 135(16):1311-1318. PubMed ID: 32107533
[TBL] [Abstract] [Full Text] [Related]
16. A Multifunctional Therapy Approach for cancer: Targeting Raf1- Mediated Inhibition of Cell Motility, Growth, and Interaction with the Microenvironment.
Zhang L; Pattanayak A; Li W; Ko HK; Fowler G; Gordon R; Bergan R
Mol Cancer Ther; 2020 Jan; 19(1):39-51. PubMed ID: 31582531
[TBL] [Abstract] [Full Text] [Related]
17. Dysregulated mitogen-activated protein kinase pathway mediated cell cycle disruption in sporadic parathyroid tumors.
Arya AK; Singh P; Saikia UN; Sachdeva N; Dahiya D; Behera A; Rao SD; Bhadada SK
J Endocrinol Invest; 2020 Feb; 43(2):247-253. PubMed ID: 31535356
[TBL] [Abstract] [Full Text] [Related]
18. Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic map2k1 Mutations.
Jha S; Fratzl-Zelman N; Roschger P; Papadakis GZ; Cowen EW; Kang H; Lehky TJ; Alter K; Deng Z; Ivovic A; Flynn L; Reynolds JC; Dasgupta A; Miettinen M; Lange E; Katz J; Klaushofer K; Marini JC; Siegel RM; Bhattacharyya T
J Bone Miner Res; 2019 Jan; 34(1):145-156. PubMed ID: 30138550
[TBL] [Abstract] [Full Text] [Related]
19. Chondroblastoma-like tumor of the skull in a patient with cardio-facio-cutaneous syndrome.
Fasciano D; Wei S; Li R; Siegal GP
Pathol Res Pract; 2018 Sep; 214(9):1510-1513. PubMed ID: 30100356
[TBL] [Abstract] [Full Text] [Related]
20. Clinicopathologic and molecular features in hairy cell leukemia-variant: single institutional experience.
Angelova EA; Medeiros LJ; Wang W; Muzzafar T; Lu X; Khoury JD; Ravandi F; Patel KP; Hu Z; Kanagal-Shamanna R
Mod Pathol; 2018 Nov; 31(11):1717-1732. PubMed ID: 29955146
[TBL] [Abstract] [Full Text] [Related]
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