BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
85 results:

  • 1. Pediatric parosteal osteosarcoma of the distal radius causing extensive erosive mass effect of the adjacent ulna: a case report.
    Perloff A; Park S; Panganiban R; deVries J
    BMC Musculoskelet Disord; 2023 Dec; 24(1):950. PubMed ID: 38057715
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Detection of Novel Tyrosine Kinase Fusion Genes as Potential Therapeutic Targets in bone and Soft Tissue Sarcomas Using DNA/RNA-based Clinical Sequencing.
    Hasegawa N; Hayashi T; Niizuma H; Kikuta K; Imanishi J; Endo M; Ikeuchi H; Sasa K; Sano K; Hirabayashi K; Takagi T; Ishijima M; Kato S; Kohsaka S; Saito T; Suehara Y
    Clin Orthop Relat Res; 2024 Mar; 482(3):549-563. PubMed ID: 38014853
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The Landscape of Alterations from 1407 Ultra-Rare Sarcomas from the AACR GENIE Database: Clinical Implications.
    Denu RA; Moyers JT; Gouda MA; Conley AP; Lazar AJ; Subbiah V
    Clin Cancer Res; 2023 Nov; 29(22):4669-4678. PubMed ID: 37643131
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. KDM2B-Rearranged Soft Tissue Sarcomas Expand the Concept of BCOR-Associated Sarcoma.
    Motoi T; Hirata M; Kukita Y; Satomi K; Tamura H; Adachi S; Matsushita Y; Horiguchi SI; Hishima T; Ikegami M; Okuma T; Tao K; Arakawa A; Ogawa C; Matsuda K; Ichimura K; Nakamura H; Mori T; Yoshida A
    Mod Pathol; 2023 Nov; 36(11):100317. PubMed ID: 37634866
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis.
    Nirala BK; Yamamichi T; Yustein JT
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511127
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The pharmacotherapeutic management of patients with myelofibrosis: looking beyond JAK inhibitors.
    Duminuco A; Vetro C; Giallongo C; Palumbo GA
    Expert Opin Pharmacother; 2023; 24(13):1449-1461. PubMed ID: 37341682
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. MicroRNA-215-5p promotes proliferation, invasion, and inhibits apoptosis in liposarcoma cells by targeting mdm2.
    Song Z; Bai J; Jiang R; Wu J; Yang W
    Cancer Med; 2023 Jun; 12(12):13455-13470. PubMed ID: 37132262
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  • 8. Reduced murine double minute 2 and 4 protein, but not messenger RNA, expression is associated with more severe disease in myelodysplastic syndromes and acute myeloblastic leukaemia.
    Salomao N; Maslah N; Giulianelli A; Drevon L; Aguinaga L; Gu X; Cassinat B; Giraudier S; Fenaux P; Fahraeus R
    Br J Haematol; 2023 Apr; 201(2):234-248. PubMed ID: 36546586
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Novel Therapies in Myelofibrosis: Beyond JAK Inhibitors.
    Waksal JA; Mascarenhas J
    Curr Hematol Malig Rep; 2022 Oct; 17(5):140-154. PubMed ID: 35984598
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. p53 as a unique target of action of cisplatin in acute leukaemia cells.
    Kumar S; Tchounwou PB
    J Cell Mol Med; 2022 Sep; 26(17):4727-4739. PubMed ID: 35946055
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors.
    Timmerman DM; Eleveld TF; Sriram S; Dorssers LCJ; Gillis AJM; Schmidtova S; Kalavska K; van de Werken HJG; Oing C; Honecker F; Mego M; Looijenga LHJ
    J Clin Oncol; 2022 Sep; 40(26):3077-3087. PubMed ID: 35442716
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Emerging drugs for the treatment of myelofibrosis: phase II & III clinical trials.
    Tremblay D; Hoffman R
    Expert Opin Emerg Drugs; 2021 Dec; 26(4):351-362. PubMed ID: 34875179
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Ouabain Induces DNA Damage in Human Osteosarcoma U-2 OS Cells and Alters the Expression of DNA Damage and DNA Repair-associated Proteins.
    Yang JL; Yang MD; Chen JC; Lu KW; Huang YP; Peng SF; Chueh FS; Liu KC; Lin TS; Chen PY; Chen WJ
    In Vivo; 2021; 35(5):2687-2696. PubMed ID: 34410957
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Recent Advances in Pathology: the 2021 Annual Review Issue of The Journal of Pathology.
    Herrington CS; Poulsom R; Koeppen H; Coates PJ
    J Pathol; 2021 Jul; 254(4):303-306. PubMed ID: 34097314
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Next Generation Therapeutics for the treatment of Myelofibrosis.
    Tremblay D; Mascarenhas J
    Cells; 2021 Apr; 10(5):. PubMed ID: 33925695
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Novel Targeted Therapeutics in Acute Myeloid Leukemia: an Embarrassment of Riches.
    Grieselhuber NR; Mims AS
    Curr Hematol Malig Rep; 2021 Apr; 16(2):192-206. PubMed ID: 33738705
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Inhibition of G Protein-Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth.
    Crudden C; Shibano T; Song D; Dragomir MP; Cismas S; Serly J; Nedelcu D; Fuentes-Mattei E; Tica A; Calin GA; Girnita A; Girnita L
    Cancer Res; 2021 Jan; 81(2):501-514. PubMed ID: 33158816
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal Hematopoietic Cells.
    Thadi A; Lewis L; Goldstein E; Aggarwal A; Khalili M; Steele L; Polyak B; Seydafkan S; Bluth MH; Ward KA; Styler M; Campbell PM; Pincus MR; Bowne WB
    Anticancer Res; 2020 Sep; 40(9):4857-4867. PubMed ID: 32878773
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Dedifferentiated Liposarcoma: Systemic Therapy Options.
    Gahvari Z; Parkes A
    Curr Treat Options Oncol; 2020 Feb; 21(2):15. PubMed ID: 32026050
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A stimuli-responsive combination therapy for recovering p53-inactivation associated drug resistance.
    Guo L; Xu Y; Zhou A; Zhang L; Sun L; Gao Y; Chen J; Shan X; Zhang J; Ge J; An X; Liu X; Zhang Y; Ning X
    Mater Sci Eng C Mater Biol Appl; 2020 Mar; 108():110403. PubMed ID: 31923941
    [TBL] [Abstract] [Full Text] [Related]  


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