Terms: = Bone cancer AND NUP98, NUP196, 4928, ADIR2, ENSG00000110713
51 results:
1. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
Abla O; Ries RE; Triche T; Gerbing RB; Hirsch B; Raimondi S; Cooper T; Farrar JE; Buteyn N; Harmon LM; Wen H; Deshpande AJ; Kolb EA; Gamis AS; Aplenc R; Alonzo T; Meshinchi S
Blood Adv; 2024 Apr; 8(8):2005-2017. PubMed ID: 38306602
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2. Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice.
An W; Feola M; Levy M; Aluri S; Ruiz-Martinez M; Sridharan A; Fibach E; Zhu X; Verma A; Ginzburg Y
Elife; 2023 Dec; 12():. PubMed ID: 38153418
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3. The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression.
Kfoury YS; Ji F; Jain E; Mazzola M; Schiroli G; Papazian A; Mercier F; Sykes DB; Kiem A; Randolph M; Calvi LM; Abdel-Wahab O; Sadreyev RI; Scadden DT
Blood Adv; 2023 Nov; 7(21):6608-6623. PubMed ID: 37450380
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4. A global study for acute myeloid leukemia with RARG rearrangement.
Zhu HH; Qin YZ; Zhang ZL; Liu YJ; Wen LJ; You MJ; Zhang C; Such E; Luo H; Yuan HJ; Zhou HS; Liu HX; Xu R; Li J; Li JH; Hao JP; Jin J; Yu L; Zhang JY; Liu LP; Zhang LP; Huang RB; Shen SH; Gao SJ; Wang W; Yan XJ; Zhang XY; Du X; Chu XX; Yu YF; Wang Y; Mi YC; Lu Y; Cai Z; Su Z; Taussig DC; MacMahon S; Ball ED; Wang HY; Welch JS; Yin CC; Borthakur G; Sanz MA; Kantarjian HM; Huang JY; Hu J; Chen SN
Blood Adv; 2023 Jul; 7(13):2972-2982. PubMed ID: 36799929
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5. Clinical utility of genomic profiling of AML using paraffin-embedded bone marrow clots: HM-SCREEN-Japan 01.
Hosono N; Chi S; Yamauchi T; Fukushima K; Shibayama H; Katagiri S; Gotoh A; Eguchi M; Morishita T; Ogasawara R; Kondo T; Yanada M; Yamamoto K; Kobayashi T; Kuroda J; Usuki K; Utsu Y; Yoshimitsu M; Ishitsuka K; Ono T; Takahashi N; Iyama S; Kojima K; Nakamura Y; Fukuhara S; Izutsu K; Abutani H; Yamauchi N; Yuda J; Minami Y;
Cancer Sci; 2023 May; 114(5):2098-2108. PubMed ID: 36793248
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6. Mixed phenotype acute leukemia in a child associated with a nup98-NSD1 fusion and NRAS p.Gly61Arg mutation.
Ganapathi SS; Raikar SS; Yatsenko SA; Djokic M; Bukowinski A
Cancer Rep (Hoboken); 2021 Aug; 4(4):e1372. PubMed ID: 33784031
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7. Alkaloid-based regimen is beneficial for acute myeloid leukemia resembling acute promyelocytic leukemia with nup98/RARG fusion and RUNX1 mutation: A case report.
Wei W; Liu Q; Song F; Cao H; Liu M; Jiang Y; Li Y; Gao S
Medicine (Baltimore); 2020 Oct; 99(40):e22488. PubMed ID: 33019444
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8. Increased FGF-23 levels are linked to ineffective erythropoiesis and impaired bone mineralization in myelodysplastic syndromes.
Weidner H; Baschant U; Lademann F; Ledesma Colunga MG; Balaian E; Hofbauer C; Misof BM; Roschger P; Blouin S; Richards WG; Platzbecker U; Hofbauer LC; Rauner M
JCI Insight; 2020 Aug; 5(15):. PubMed ID: 32759495
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9. Characterizing false-positive fluorescence in situ hybridization results by mate-pair sequencing in a patient with chronic myeloid leukemia and progression to myeloid blast crisis.
Lopes JL; Webley M; Pitel BA; Pearce KE; Smadbeck JB; Johnson SH; Vasmatzis G; Sukov WR; Greipp PT; Hoppman NL; Ketterling RP; Baughn LB; Finn L; Peterson JF
Cancer Genet; 2020 May; 243():48-51. PubMed ID: 32272434
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10. SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
Chen BY; Song J; Hu CL; Chen SB; Zhang Q; Xu CH; Wu JC; Hou D; Sun M; Zhang YL; Liu N; Yu PC; Liu P; Zong LJ; Zhang JY; Dai RF; Lan F; Huang QH; Zhang SJ; Nimer SD; Chen Z; Chen SJ; Sun XJ; Wang L
Blood; 2020 Jun; 135(25):2271-2285. PubMed ID: 32202636
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11. Thymic precursor cells generate acute myeloid leukemia in nup98-PHF23/nup98-HOXD13 double transgenic mice.
Kundu S; Park ES; Chung YJ; Walker RL; Zhu YJ; Negi V; Meltzer PS; Aplan PD
Sci Rep; 2019 Nov; 9(1):17213. PubMed ID: 31748606
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12. Dasatinib and navitoclax act synergistically to target nup98-NSD1
Kivioja JL; Thanasopoulou A; Kumar A; Kontro M; Yadav B; Majumder MM; Javarappa KK; Eldfors S; Schwaller J; Porkka K; Heckman CA
Leukemia; 2019 Jun; 33(6):1360-1372. PubMed ID: 30568173
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13. Clinical Evaluation of Massively Parallel RNA Sequencing for Detecting Recurrent Gene Fusions in Hematologic Malignancies.
Kim B; Lee H; Shin S; Lee ST; Choi JR
J Mol Diagn; 2019 Jan; 21(1):163-170. PubMed ID: 30347268
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14. Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome.
Chung YJ; Khawaja G; Wolcott KM; Aplan PD
J Vis Exp; 2018 Oct; (140):. PubMed ID: 30346380
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15. Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation.
Bhagat TD; Chen S; Bartenstein M; Barlowe AT; Von Ahrens D; Choudhary GS; Tivnan P; Amin E; Marcondes AM; Sanders MA; Hoogenboezem RM; Kambhampati S; Ramachandra N; Mantzaris I; Sukrithan V; Laurence R; Lopez R; Bhagat P; Giricz O; Sohal D; Wickrema A; Yeung C; Gritsman K; Aplan P; Hochedlinger K; Yu Y; Pradhan K; Zhang J; Greally JM; Mukherjee S; Pellagatti A; Boultwood J; Will B; Steidl U; Raaijmakers MHGP; Deeg HJ; Kharas MG; Verma A
Cancer Res; 2017 Sep; 77(18):4846-4857. PubMed ID: 28684528
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16. Copy number alterations determined by single nucleotide polymorphism array testing in the clinical laboratory are indicative of gene fusions in pediatric cancer patients.
Busse TM; Roth JJ; Wilmoth D; Wainwright L; Tooke L; Biegel JA
Genes Chromosomes Cancer; 2017 Oct; 56(10):730-749. PubMed ID: 28597942
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17. nup98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.
Struski S; Lagarde S; Bories P; Puiseux C; Prade N; Cuccuini W; Pages MP; Bidet A; Gervais C; Lafage-Pochitaloff M; Roche-Lestienne C; Barin C; Penther D; Nadal N; Radford-Weiss I; Collonge-Rame MA; Gaillard B; Mugneret F; Lefebvre C; Bart-Delabesse E; Petit A; Leverger G; Broccardo C; Luquet I; Pasquet M; Delabesse E
Leukemia; 2017 Mar; 31(3):565-572. PubMed ID: 27694926
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18. nup98-PHF23 fusion is recurrent in acute myeloid leukemia and shares gene expression signature of leukemic stem cells.
Ho H; Skaist AM; Pallavajjala A; Yonescu R; Batista D; Wheelan SJ; Ning Y
Leuk Res; 2016 Jun; 45():1-7. PubMed ID: 27060678
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19. PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.
Guirguis AA; Slape CI; Failla LM; Saw J; Tremblay CS; Powell DR; Rossello F; Wei A; Strasser A; Curtis DJ
Cell Death Differ; 2016 Jun; 23(6):1049-59. PubMed ID: 26742432
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20. Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of nup98-RARG leukemia.
Qiu JJ; Zeisig BB; Li S; Liu W; Chu H; Song Y; Giordano A; Schwaller J; Gronemeyer H; Dong S; So CW
Leukemia; 2015 May; 29(5):1153-62. PubMed ID: 25510432
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