BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Bone cancer AND PIM1, PIM, 5292, ENSG00000137193, P11309 AND Treatment
20 results:

  • 1. An overview of pim kinase as a target in multiple myeloma.
    Liu Z; Zhang Y; Guo Y; Wang H; Fu R
    Cancer Med; 2023 May; 12(10):11746-11759. PubMed ID: 37162273
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. pim2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma.
    Haas M; Caron G; Chatonnet F; Manenti S; Alaterre E; Devin J; Delaloy C; Bertolin G; Viel R; Pignarre A; Llamas-Gutierrez F; Marchalot A; Decaux O; Tarte K; Delpy L; Moreaux J; Fest T
    Blood; 2022 Apr; 139(15):2316-2337. PubMed ID: 35108359
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genetic ablation of pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models.
    Dutta A; Nath D; Yang Y; Le BT; Rahman MF; Faughnan P; Wang Z; Stuver M; He R; Tan W; Hutchison RE; Foulks JM; Warner SL; Zang C; Mohi G
    Leukemia; 2022 Mar; 36(3):746-759. PubMed ID: 34741118
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. LncRNA RGMB-AS1 facilitates pancreatic cancer cell proliferation and migration but inhibits cell apoptosis via miR-574-3p/pim3 axis.
    Song W; Shi C
    Am J Physiol Gastrointest Liver Physiol; 2021 Nov; 321(5):G477-G488. PubMed ID: 34468207
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Therapeutic Efficacy of Combined JAK1/2, Pan-pim, and CDK4/6 Inhibition in Myeloproliferative Neoplasms.
    Rampal RK; Pinzon-Ortiz M; Somasundara AVH; Durham B; Koche R; Spitzer B; Mowla S; Krishnan A; Li B; An W; Derkach A; Devlin S; Rong X; Longmire T; Eisman SE; Cordner K; Whitfield JT; Vanasse G; Cao ZA; Levine RL
    Clin Cancer Res; 2021 Jun; 27(12):3456-3468. PubMed ID: 33782031
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Design and synthesis of a novel mitochondria-targeted osteosarcoma theranostic agent based on a pim1 kinase inhibitor.
    Yi X; Cao Z; Yuan Y; Li W; Cui X; Chen Z; Hu X; Yu A
    J Control Release; 2021 Apr; 332():434-447. PubMed ID: 33662457
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. 68Ga-DOTATOC-PET/CT-guided resection of a primary intraosseous meningioma: technical note.
    Guinto-Nishimura GY; Gómez-Amador JL; Kerik-Rotenberg N; Uribe-Pacheco R; Sangrador-Deitos MV; Martínez-Manrique JJ
    Neurosurg Focus; 2021 Jan; 50(1):E6. PubMed ID: 33386007
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Primary intraosseous meningioma of the calvarium: A systematic review.
    Omofoye OA; Huynh T; Jhun R; Ashfaque H; Cronk K
    Clin Neurol Neurosurg; 2020 Dec; 199():106283. PubMed ID: 33069929
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia.
    Hu X; Chen F
    Hematology; 2019 Dec; 24(1):651-660. PubMed ID: 31533545
    [No Abstract]    [Full Text] [Related]  

  • 10. Single-centre Experience of Use of Radium 223 with Clinical Outcomes Based on Number of Cycles and bone Marrow Toxicity.
    Dadhania S; Alonzi R; Douglas S; Gogbashian A; Hughes R; Dalili D; Vasdev N; Adshead J; Lane T; Westbury C; Anyamene N; Ostler P; Hoskin P; Sharma A
    Anticancer Res; 2018 Sep; 38(9):5423-5427. PubMed ID: 30194198
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia.
    Minieri V; De Dominici M; Porazzi P; Mariani SA; Spinelli O; Rambaldi A; Peterson LF; Porcu P; Nevalainen MT; Calabretta B
    Cancer Res; 2018 Oct; 78(20):5793-5807. PubMed ID: 30154155
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.
    Doshi KA; Trotta R; Natarajan K; Rassool FV; Tron AE; Huszar D; Perrotti D; Baer MR
    Oncotarget; 2016 Jul; 7(30):48280-48295. PubMed ID: 27374090
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Clinical and biological significance of pim1 kinase in osteosarcoma.
    Liao Y; Feng Y; Shen J; Gao Y; Cote G; Choy E; Harmon D; Mankin H; Hornicek F; Duan Z
    J Orthop Res; 2016 Jul; 34(7):1185-94. PubMed ID: 26687194
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Targeting the pim kinases in multiple myeloma.
    Keane NA; Reidy M; Natoni A; Raab MS; O'Dwyer M
    Blood Cancer J; 2015 Jul; 5(7):e325. PubMed ID: 26186558
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. XCR1 promotes cell growth and migration and is correlated with bone metastasis in non-small cell lung cancer.
    Wang T; Han S; Wu Z; Han Z; Yan W; Liu T; Wei H; Song D; Zhou W; Yang X; Xiao J
    Biochem Biophys Res Commun; 2015 Aug; 464(2):635-41. PubMed ID: 26166822
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Novel myelofibrosis treatment strategies: potential partners for combination therapies.
    Stein BL; Swords R; Hochhaus A; Giles F
    Leukemia; 2014 Nov; 28(11):2139-47. PubMed ID: 24888274
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling.
    Cen B; Xiong Y; Song JH; Mahajan S; DuPont R; McEachern K; DeAngelo DJ; Cortes JE; Minden MD; Ebens A; Mims A; LaRue AC; Kraft AS
    Mol Cell Biol; 2014 Jul; 34(13):2517-32. PubMed ID: 24777602
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. eIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes.
    Yang J; Wang J; Chen K; Guo G; Xi R; Rothman PB; Whitten D; Zhang L; Huang S; Chen JL
    Cancer Res; 2013 Aug; 73(15):4898-908. PubMed ID: 23749639
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.
    Jin L; Tabe Y; Lu H; Borthakur G; Miida T; Kantarjian H; Andreeff M; Konopleva M
    Cancer Lett; 2013 Feb; 329(1):45-58. PubMed ID: 23036488
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Autologous bone marrow transplantation in children with advanced neuroblastoma.
    Mugishima H; Iwata M; Okabe I; Sanuki E; Onuma N; Fujimoto T; Ohira M; Kaneko M; Tsuchida Y; Okuni M
    Cancer; 1994 Aug; 74(3):972-7. PubMed ID: 8039127
    [TBL] [Abstract] [Full Text] [Related]  


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